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Aging is thought to be a consequence of intrinsic breakdowns in how genetic information is processed. But mounting experimental evidence suggests that aging can be slowed. To help resolve this mystery, I derive a mortality equation which…

种群与进化 · 定量生物学 2022-09-01 Thomas Fink

Understanding why we age is a long-lived open problem in evolutionary biology. Aging is prejudicial to the individual and evolutionary forces should prevent it, but many species show signs of senescence as individuals age. Here, I will…

种群与进化 · 定量生物学 2012-01-24 André C. R. Martins

Models of population growth and extinction are an increasingly popular subject of study. However, consequences of stochasticity and noise in shaping distributions and outcomes are not sufficiently explored. Here we consider a distributed…

统计力学 · 物理学 2020-11-11 Bertrand Ottino-Löffler , Mehran Kardar

Evolutionary game theory has traditionally employed deterministic models to describe population dynamics. These models, due to their inherent nonlinearities, can exhibit deterministic chaos, where population fluctuations follow complex,…

种群与进化 · 定量生物学 2025-04-02 Maria Alejandra Ramirez , George Datseris , Arne Traulsen

This paper investigates a nonlinear logistic model for age-structured population dynamics. The model incorporates interdependent fertility and mortality functions within a logistic framework, offering insights into stationary solutions and…

偏微分方程分析 · 数学 2025-11-24 Dragos-Patru Covei

Frequency dependent selection and demographic fluctuations play important roles in evolutionary and ecological processes. Under frequency dependent selection, the average fitness of the population may increase or decrease based on…

种群与进化 · 定量生物学 2015-06-23 Weini Huang , Christoph Hauert , Arne Traulsen

At any moment in time, evolution is faced with a formidable challenge: refining the already highly optimised design of biological species, a feat accomplished through all preceding generations. In such a scenario, the impact of random…

种群与进化 · 定量生物学 2024-02-20 Alessandro Fontana , Marios Kyriazis

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

生物物理 · 物理学 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan

Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population…

种群与进化 · 定量生物学 2016-02-03 Arian Šajina , Dario Riccardo Valenzano

The evolutionary biology of aging is fundamental to understanding the mechanisms of aging and how to develop anti-aging treatments. Thus far most evolutionary theory concerns the genetics of aging with limited physiological integration.…

种群与进化 · 定量生物学 2025-09-22 Mirre J P Simons , Marc Tatar

Neutral dynamics, where taxa are assumed to be demographically equivalent and their abundance is governed solely by the stochasticity of the underlying birth-death process, has proved itself as an important minimal model that accounts for…

种群与进化 · 定量生物学 2015-09-09 David Kessler , Samir Suweis , Marco Formentin , Nadav M. Shnerb

We study an ecology-inspired model for a population of bounded size, whose dynamics is governed by random birth, death, and immigration events. Stochastic fluctuations in the number of individuals give rise to a succession of alternating…

种群与进化 · 定量生物学 2026-05-27 Lucas M. Brugevin , Damián H. Zanette

Ignoring the differences between countries, human reproductive and dispersal behaviors can be described by some standardized models, so whether there is a universal law of population growth hidden in the abundant and unstructured data from…

物理与社会 · 物理学 2024-02-08 Jiajun Ma , Qinghua Chen , Xiaosong Chen , Jingfang Fan , Xiaomeng Li , Yi Shi

Standard evolutionary theories of aging and mortality, implicitly based on assumptions of spatial averaging, hold that natural selection cannot favor shorter lifespan without direct compensating benefit to individual reproductive success.…

种群与进化 · 定量生物学 2015-06-15 Justin Werfel , Donald E. Ingber , Yaneer Bar-Yam

Population dynamics in random ecological networks are investigated by analyzing a simple deterministic equation. It is found that a sequence of abrupt changes of populations punctuating quiescent states characterize the long time behavior.…

chao-dyn · 物理学 2008-02-03 Shin-ichi Sasa , Tsuyoshi Chawanya

A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-driven changes in full age-specific demographic schedules. The…

种群与进化 · 定量生物学 2007-05-23 David Steinsaltz , Steven N. Evans , Kenneth W. Wachter

The chronological age used in demography describes the linear evolution of the life of a living being. The chronological age cannot give precise information about the exact developmental stage or aging processes an organism has reached. On…

偏微分方程分析 · 数学 2023-10-02 Jacques Demongeot , Pierre Magal

Logistic functions are good models of biological population growth. They are also popular in marketing in modelling demand-supply curves and in a different context, to chart the sales of new products over time. Delays being inherent in any…

种群与进化 · 定量生物学 2012-11-30 Milind M. Rao , K. L. Preetish

Evolution occurs in populations of reproducing individuals. The structure of a biological population affects which traits evolve. Understanding evolutionary game dynamics in structured populations is difficult. Precise results have been…

种群与进化 · 定量生物学 2017-08-16 Benjamin Allen , Gabor Lippner , Yu-Ting Chen , Babak Fotouhi , Naghmeh Momeni , Martin A. Nowak , Shing-Tung Yau

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

种群与进化 · 定量生物学 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer
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