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The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Elena Cebrian

Bacterial growth and division generally occur by the process known as binary fission, in which the cells grow polarly until they divide into two daughter cells. Although this process is affected by factors that introduce stochastic…

软凝聚态物质 · 物理学 2022-10-05 Andrés Delgado-Campos , Alejandro Cuetos

We introduce two stochastic chemostat models consisting in a coupled population-nutrient process reflecting the interaction between the nutrient and the bacterias in the chemostat with finite volume. The nutrient concentration evolves…

概率论 · 数学 2012-06-19 Pierre Collet , Servet Martinez , Sylvie Meleard , Jaime San Martin

Cell colonies of bacteria, tumour cells and fungi, under nutrient limited growth conditions, exhibit complex branched growth patterns. In order to investigate this phenomenon we present a simple hybrid cellular automaton model of cell…

生物物理 · 物理学 2007-05-23 P. Gerlee , A. R. A Anderson

A time- and space-discrete model for the growth of a rapidly saturating local biological population $N(x,t)$ is derived from a hierarchical random deposition process previously studied in statistical physics. Two biologically relevant…

生物物理 · 物理学 2009-11-07 J. O. Indekeu , K. Sznajd-Weron

Bacterial cells navigate around their environment by directing their movement along chemical gradients. This process, known as chemotaxis, can promote the rapid expansion of bacterial populations into previously unoccupied territories.…

种群与进化 · 定量生物学 2022-06-08 Avaneesh V. Narla , Jonas Cremer , Terry Hwa

A stochastic model is used to assess the effect of external parameters on the development of submerged biofilms on smooth and rough surfaces. The model includes basic cellular mechanisms, such as division and spreading, together with an…

软凝聚态物质 · 物理学 2024-01-17 David Rodriguez , Baldvin Einarsson , Ana Carpio

This paper theoretically analyzes a phenomenological stochastic model for bacterial growth. This model comprises cell division and the linear growth of cells, where growth rates and cell cycles are drawn from lognormal distributions. We…

生物物理 · 物理学 2016-06-28 Ken Yamamoto , Jun-ichi Wakita

Adaptive control in biological systems, such as intestinal immunity, remains poorly understood despite detailed knowledge of underlying regulatory networks. We propose an alternative framework based on stochastic martingale turnover, in…

适应与自组织系统 · 物理学 2026-05-01 Tomoyuki Yamaguchi

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

统计力学 · 物理学 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

定量方法 · 定量生物学 2007-05-23 Leah R. Johnson

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

生物物理 · 物理学 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

Nutrient gradients and limitations play a pivotal role in the life of all microbes, both in their natural habitat as well as in artificial, microfluidic systems. Spatial concentration gradients of nutrients in densely packed cell…

We propose a model of chemostat where the bacterial population is individually-based, each bacterium is explicitly represented and has a mass evolving continuously over time. The substrate concentration is represented as a conventional…

概率论 · 数学 2013-11-08 Fabien Campillo , Coralie Fritsch

We experimentally investigate how aerotactic bacteria, confined within a thin liquid film between two solid substrates, respond to a controlled oxygen gradient. We find that the total bacterial number density dictates which mechanism…

软凝聚态物质 · 物理学 2026-04-07 Minjun Kim , Joonwoo Jeong

This paper introduces a reaction-diffusion-chemotaxis model for bacterial aggregation patterns on the surface of thin agar plates. It is based on the non-linear degenerate cross diffusion model proposed by Kawasaki et al. (J. of Theor.…

细胞行为 · 定量生物学 2013-01-23 J. Francisco Leyva , Carlos Malaga , Ramon G. Plaza

The transition from monolayers to multilayered structures in bacterial colonies is a fundamental step in biofilm development. Observed across different morphotypes and species, this transition is triggered within freely growing bacterial…

软凝聚态物质 · 物理学 2021-03-16 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

Bacteria generally live in complicated structures called biofilms, consisting of communicating bacterial colonies and extracellular polymeric substance (EPS). Since biofilms are related to detrimental effects such as infection or antibiotic…

定量方法 · 定量生物学 2023-11-07 Fatih Gulec , Andrew W. Eckford

The ubiquitous existence of microbial communities marks the importance of understanding how species interact within the community to coexist and their spatial organization. We study a two-species mutualistic cross-feeding model through a…

种群与进化 · 定量生物学 2022-10-31 Jiaqi. Lin , Hui. Sun , JiaJia Dong

We present a model for a biological reactor in which bacteria tend to aggregate in flocs, as encountered in wastewater treatment plants. The influence of this flocculation on the growth dynamics of the bacteria is studied. We argue that a…

种群与进化 · 定量生物学 2007-05-23 Bart Haegeman , Claude Lobry , Jerome Harmand
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