相关论文: Fold-Hopf Bursting in a Model for Calcium Signal T…
Bursting is a phenomenon found in a variety of physical and biological systems. For example, in neuroscience, bursting is believed to play a key role in the way information is transferred in the nervous system. In this work, we propose a…
Bursting is a periodic transition between a quiescent state and a state of repetitive spiking. The phenomenon is ubiquitous in a variety of neurophysical systems. We numerically study the dynamical properties of a normal form of subcritical…
Rapid action potential generation --- spiking --- and alternating intervals of spiking and quiescence --- bursting --- are two dynamic patterns observed in neuronal activity. In computational models of neuronal systems, the transition from…
In this letter we present the results of a simple model for intercellular communication via calcium oscillations, motivated in part by a recent experimental study. The model describes two cells (a "donor" and "sensor") whose intracellular…
We describe a simple conductance-based model neuron that includes intra- and extra-cellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast spiking behavior of the neuron is…
A delayed differential equation modelling a single neuron with inertial term is considered in this paper. Hopf bifurcation is studied by using the normal form theory of retarded functional differential equations. When adopting a…
In order to describe excitable reaction-diffusion systems, we derive a two-dimensional model with a Hopf and a semilocal saddle-node homoclinic bifurcation. This model gives the theoretical framework for the analysis of the saddle-node…
We study a simple map as a minimal model of excitable cells. The map has two fast variables which mimic the behavior of class I neurons, undergoing a sub-critical Hopf bifurcation. Adding a third slow variable allows the system to present…
Electro-cortical activity in patients with epilepsy may show abnormal rhythmic transients in response to stimulation. Even when using the same stimulation parameters in the same patient, wide variability in the duration of transient…
We study the quasi-periodicity phenomena occurring at the transition between tonic spiking and bursting activities in exemplary biologically plausible Hodgkin-Huxley type models of individual cells and reduced phenomenological models with…
In this article we introduce an original model in order to study the emergence of chaos in a reaction diffusion system in the presence of self- and cross-diffusion terms. A Fourier Spectral Method is derived to approximate equilibria and…
The presynaptic free calcium dynamics of neurons due to various stimulation protocols is investigated in a mathematical model. The model includes calcium influx through voltage-dependent calcium channels, calcium buffering by endogenous and…
Calcium is an ubiquitous second messenger that triggers a plethora of key physiological responses. The events are initiated in micro- or nano-sized compartments and determined by the complex interactions with calcium-binding proteins and…
Intensive computational and theoretical work has led to the development of mutliple mathematical models for bursting in respiratory neurons in the pre-B\"otzinger Complex (pre-B\"otC) of the mammalian brainstem. Nonetheless, these previous…
Intracellular calcium is regulated in part by the release of Ca$^{2+}$ ions from the endoplasmic reticulum via inositol-4,5-triphosphate receptor (IP$_3$R) channels (among other possibilities such as RyR and L-type calcium channels). The…
A simple model that replicates the dynamics of spiking and spiking-bursting activity of real biological neurons is proposed. The model is a two-dimensional map which contains one fast and one slow variable. The mechanisms behind generation…
A reaction-diffusion-advection predator-prey model with Holling type-II predator functional response is considered. We show the stability/instability of the positive steady state and the existence of a Hopf bifurcation when the diffusion…
We propose an approach to study small limit cycle bifurcations on a center manifold in analytic or smooth systems depending on parameters. We then apply it to the investigation of limit cycle bifurcations in a model of calcium oscillations…
`Bursting', defined as periods of high frequency firing of a neuron separated by periods of quiescence, has been observed in various neuronal systems, both \textit{in vitro} and \textit{in vivo}. It has been associated with a range of…
A theoretical analysis of two- and three-dimensional fractional-order Hindmarsh-Rose neuronal models is presented, focusing on stability properties and occurrence of Hopf bifurcations, with respect to the fractional order of the system…