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The biomechanical properties of blood clots, which are dictated by their compositions and micro-structures, play a critical role in determining their fates, occlusion, persistency, or embolization in the human circulatory system. While…

生物物理 · 物理学 2024-03-18 Nicholas Filla , Beikang Gu , Jixin Hou , Kenan Song , He Li , Ning Liu , Xianqiao Wang

Safe navigation for an ego vehicle in uncertain environments characterized by dynamic obstacles with unknown nonlinear dynamics is a challenging problem of significant practical interest. Existing approaches in the literature either lack…

系统与控制 · 电气工程与系统科学 2026-04-17 Jiwon Lee , Hugo Matias , Daniel Silvestre , Thinh T. Doan

Accurate and rapid estimation of hemodynamic metrics, such as pressure and wall shear stress (WSS), is important for assessing the severity of Coronary Artery Disease (CAD). Existing approaches, including invasive Fractional Flow Reserve…

计算工程、金融与科学 · 计算机科学 2026-05-28 Reza Akbarian Bafghi , Sukirt Thakur , Maziar Raissi

The study of vesicles under flow, a model system for red blood cells (RBCs), is an essential step in understanding various intricate dynamics exhibited by RBCs in vivo and in vitro. Quantitative 3D analyses of vesicles under flow are…

软凝聚态物质 · 物理学 2009-12-24 Thierry Biben , Alexander Farutin , Chaouqi Misbah

Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…

SUMMARY This work aims at quantifying the effect of inherent uncertainties from cardiac output on the sensitivity of a human compliant arterial network response based on stochastic simulations of a reduced-order pulse wave propagation…

数值分析 · 数学 2016-06-22 A Brault , L Dumas , D Lucor

Critical coagulation concentration (CCC) is a key parameter of particle dispersions, since it provides the threshold limit of electrolyte concentrations, above which the dispersions are destabilized due to rapid particle aggregation. A…

软凝聚态物质 · 物理学 2020-06-08 Marco Galli , Szilard Saringer , Istvan Szilagyi , Gregor Trefalt

Many of the intriguing properties of blood originate from its cellular nature. Bulk effects, such as viscosity, depend on the local shear rates and on the size of the vessels. While empirical descriptions of bulk rheology are available for…

计算工程、金融与科学 · 计算机科学 2023-05-05 Gabor Zavodszky , Christian Spieker , Benjamin Czaja , Britt van Rooij

It is still debated how breathing interacts with the CSF. New Phase contrast MRI sequence based on Echo Planar imaging (EPI-PC) can now produce continuously during minutes a velocity map, more or less every 100 ms. We did not found in the…

信号处理 · 电气工程与系统科学 2022-07-29 Olivier Baledent , Pan Liu , Serge Metanbou , Cyrille Capel , Sidy Fall , Roger Bouzerar

Control Barrier Functions (CBFs) provide a powerful framework for ensuring safety in dynamical systems. However, their application typically relies on full state information, which is often violated in real-world due to the availability of…

系统与控制 · 电气工程与系统科学 2026-05-19 Vaishnavi Jagabathula , Ahan Basu , Pushpak Jagtap

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Recent analyses combining advanced theoretical techniques and high-quality data from thousands of simultaneously recorded neurons provide strong support for the hypothesis that neural dynamics operate near the edge of instability across…

神经元与认知 · 定量生物学 2024-03-25 Rubén Calvo , Carles Martorell , Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

Functionally significant coronary artery disease (CAD) is caused by plaque buildup in the coronary arteries, potentially leading to narrowing of the arterial lumen, i.e. coronary stenosis, that significantly obstructs blood flow to the…

图像与视频处理 · 电气工程与系统科学 2023-08-10 Nils Hampe , Sanne G. M. van Velzen , Jean-Paul Aben , Carlos Collet , Ivana Išgum

Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease that leads to increased pulmonary pressures, vascular remodeling, and eventual right ventricular (RV) failure. Pediatric PAH remains understudied due to limited…

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

Control Barrier Functions (CBFs) have emerged as a powerful paradigm in control theory, providing a principled approach to enforcing safety-critical constraints in dynamic systems. This survey paper comprehensively explores the foundational…

系统与控制 · 电气工程与系统科学 2024-08-27 Promit Panja

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

神经元与认知 · 定量生物学 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

It is well known that in the computational fluid dynamics simulations related to the cardiovascular system the enforcement of outflow boundary conditions is a crucial point. In fact, they highly affect the computed flow and a wrong setup…

流体动力学 · 物理学 2025-03-05 Zahra Mirzaiyan , Michele Girfoglio , Gianluigi Rozza

Cardiometabolic diseases have substantially increased in China in the past 20 years and blood pressure is a primary modifiable risk factor. Using data from the China Health and Nutrition Survey, we examine blood pressure trends in China…

应用统计 · 统计学 2015-11-06 Luke B. Smith , Montserrat Fuentes , Penny Gordon-Larsen , Brian J. Reich

Five parameters of a model of a polymer electrolyte membrane fuel cell cathode (the porosity of the gas diffusion layer, the porosity of the catalyst layer, the exchange current density of the oxygen reduction reaction, the effective ionic…

材料科学 · 物理学 2013-08-22 Qingzhi Guo , Vijay A. Sethuraman , Ralph E. White