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Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

机器学习 · 计算机科学 2021-11-11 Mohammad Farajtabar , Mohit Biglarian , Morteza Miansari

Lead is a naturally-occurring element. It has been known to man for a long time, and it is one of the longest established poisons. The current consensus is that no level of lead exposure should be deemed "safe." New evidence regarding the…

定量方法 · 定量生物学 2019-02-19 Anca Radulescu , Steven Lundgren

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

流体动力学 · 物理学 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

软凝聚态物质 · 物理学 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

Cardiopulmonary resuscitation (CPR) is one of the essential tools to ensure oxygen supply during cardiac arrest. However, the precise effects of chest compression are not quantifiable to this day. This often results in a low quality of…

Cross-frequency coupling (CFC) has been proposed to coordinate neural dynamics across spatial and temporal scales. Despite its potential relevance for understanding healthy and pathological brain function, the standard CFC analysis and…

神经元与认知 · 定量生物学 2014-10-08 Juhan Aru , Jaan Aru , Viola Priesemann , Michael Wibral , Luiz Lana , Gordon Pipa , Wolf Singer , Raul Vicente

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

机器学习 · 计算机科学 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Recent studies show the existing clinical tests to detect Cardio/cerebrovascular diseases (CVD) are ineffectual as they do not consider different stages of platelet activation or the molecular dynamics involved in platelet interactions.…

Correlating neural communication in brain networks with behavior and cognition can provide fundamental insights into the functionality of both healthy and diseased brains. We demonstrate how communication in the brain can be estimated from…

信号处理 · 电气工程与系统科学 2023-06-21 Felix Schwock , Julien Bloch , Les Atlas , Shima Abadi , Azadeh Yazdan-Shahmorad

Alignment between subjective sense of time and chronological time can become skewed as a result of pharmacological interventions, neurodegenerative diseases (such as Parkinson's disease), or even in the moments preceding brain death.…

神经元与认知 · 定量生物学 2025-05-13 Irina Kareva , Georgy Karev

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

流体动力学 · 物理学 2008-11-11 Renat A. Sultanov , Dennis Guster

We propose a control barrier function (CBF) formulation for enforcing equality and inequality constraints in variational inference. The key idea is to define a barrier functional on the space of probability density functions that encode the…

最优化与控制 · 数学 2026-05-15 Yinzhuang Yi , Jorge Cortés , Nikolay Atanasov

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and sustained hypertension is an often silent risk factor, making cuffless continuous blood pressure (BP) monitoring with wearable devices important for…

信号处理 · 电气工程与系统科学 2025-12-02 Yiqiao Chen , Fazheng Xu , Zijian Huang , Juchi He , Zhenghui Feng

The relationship between blood flow and neuronal activity is widely recognized, with blood flow frequently serving as a surrogate for neuronal activity in fMRI studies. At the microscopic level, neuronal activity has been shown to influence…

神经元与认知 · 定量生物学 2023-06-29 Yoni Choukroun , Lior Golgher , Pablo Blinder , Lior Wolf

Classification of cognitive workload promises immense benefit in diverse areas ranging from driver safety to augmenting human capability through closed loop brain computer interface. The brain is the most metabolically active organ in the…

信号处理 · 电气工程与系统科学 2022-10-07 Harry J. Davies , Ian Williams , Ghena Hammour , Metin Yarici , Barry M. Seemungal , Danilo P. Mandic

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

The brain produces rhythms in a variety of frequency bands. Some are likely by-products of neuronal processes; others are thought to be top-down. Produced entirely naturally, these rhythms have clearly recognizable beats, but they are very…

动力系统 · 数学 2020-06-09 Benjamin Ambrosio , Lai-Sang Young

Measured responses from visual cortical neurons show that spike times tend to be correlated rather than exactly Poisson distributed. Fano factors vary and are usually greater than 1 due to the tendency of spikes being clustered into bursts.…

神经元与认知 · 定量生物学 2007-05-23 Alexander Lerchner , Mandana Ahmadi , John Hertz

Heart rate variability (HRV), defined as the variability between consecutive heartbeats, is a surrogate measure of cardiac vagal tone. It is widely accepted that a decreased HRV is associated to several risk factors and cardiovascular…

医学物理 · 物理学 2021-05-20 Stefania Scarsoglio , Luca Ridolfi

Mammalian brains span about 4 orders of magnitude in cortical volume and have to operate in different environments that require diverse behavioral skills. Despite these geometric and behavioral diversities, the examination of cerebral…

神经元与认知 · 定量生物学 2014-05-19 Jan Karbowski