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Background: Renal blood flow (RBF) is an important marker of kidney health, but noninvasive assessment is not routinely used in clinical imaging. We evaluated the feasibility and physiologic validity of quantifying renal transport of…

We present experimental evidence of multiple blood flow configurations in a relatively simple microfluidic network under constant inlet conditions. We provide evidence of multistability and unsteady dynamics and find good agreement with a…

流体动力学 · 物理学 2024-10-08 Mathieu Alonzo , Nathaniel J. Karst , Thomas Podgorski , John B. Geddes , Gwennou Coupier

Flow of cerebrospinal fluid in perivascular spaces is a key mechanism underlying brain transport and clearance. In this paper, we present a mathematical and numerical formalism for reduced models of pulsatile viscous fluid flow in networks…

流体动力学 · 物理学 2021-11-25 Cécile Daversin-Catty , Ingeborg G. Gjerde , Marie E. Rognes

This study investigates the hemodynamic behavior of blood flow in the aortic arch across anemic, diabetic, and healthy conditions using computational fluid dynamics (CFD) simulations with a non-Newtonian Carreau viscosity model. Velocity…

流体动力学 · 物理学 2025-06-23 Farzana Akter Tina , Hashnayne Ahmed , Hena Rani Biswas

The impulse response function (IRF) of a localized bolus in cerebral blood flow codes important information on the tissue type. It is indirectly accessible both from MR- and CT-imaging methods, at least in principle. In practice, however,…

组织与器官 · 定量生物学 2014-09-30 Evelyn Rost , Ralf Geske , Michael Baake

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

The liver has a unique blood supply system and plays an important role in the human blood circulatory system. Thus, hemodynamic problems related to the liver serve as an important part in clinical diagnosis and treatment. Although…

数值分析 · 数学 2021-10-15 Ting Wu , Keqin Liu , Emily Fainman , Ying Wang

It has been shown that light speckle fluctuations provide a means for noninvasive measurements of cerebral blood flow index (CBFi). While conventional Diffuse Correlation Spectroscopy (DCS) provides marginal brain sensitivity for CBFi in…

FLASH radiation has been reported to efficiently suppress tumor growth while sparing normal tissue, however, the mechanism of the differential tissue sparing effect is still not known. Oxygen has long been known to profoundly impact…

医学物理 · 物理学 2022-12-29 Hongyu Zhu , Jan Schuemann , Qixian Zhang , Leo E Gerweck

This work aims at identifying and quantifying uncertainties related to elastic and viscoelastic parameters, which characterize the arterial wall behavior, in one-dimensional modeling of the human arterial hemodynamics. The chosen uncertain…

流体动力学 · 物理学 2021-02-12 Giulia Bertaglia , Valerio Caleffi , Lorenzo Pareschi , Alessandro Valiani

The baroreceptor neurons serve as the primary transducers of blood pressure for the autonomic nervous system and are thus critical in enabling the body to respond effectively to changes in blood pressure. These neurons can be separated into…

神经元与认知 · 定量生物学 2016-09-09 Jacob Sturdy , Johnny T Ottesen , Mette S Olufsen

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…

组织与器官 · 定量生物学 2020-02-03 Nurullah Arslan , Kazim Besirli , Gurcan Comert , Omer F Beyca

Coronary artery bypass grafts (CABG) surgery is an invasive procedure performed to circumvent partial or complete blood flow blockage in coronary artery disease (CAD). In this work, we apply a numerical optimal flow control model to…

The basic parameters determining the flow pattern for a nonviscous, non-heat-conducting gas in a semidetached binary system without a magnetic field are identified. Three-dimensional gas-dynamical modeling of the mass transfer enables…

天体物理学 · 物理学 2007-05-23 D. V. Bisikalo , A. A. Boyarchuk , O. A. Kuznetsov , V. M. Chechetkin

The flow behavior of blood in microvessels is directly associated with tissue perfusion and oxygen delivery. Current efforts on modeling blood flow have primarily focused on the flow properties of blood with red blood cells (RBCs) having a…

软凝聚态物质 · 物理学 2024-06-03 Wei Chien , Gerhard Gompper , Dmitry A. Fedosov

This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics…

Cerebral autoregulation refers to regulation mechanisms that aim to maintain cerebral blood flow approximately constant. It is often assessed by autoregulation index (ARI), which uses arterial blood pressure and cerebral blood flow velocity…

组织与器官 · 定量生物学 2017-01-02 Adam Mahdi , Erica Rutter , Stephen J. Payne

A network-based approach is presented to investigate the cerebrovascular flow patterns during atrial fibrillation (AF) with respect to normal sinus rhythm (NSR). AF, the most common cardiac arrhythmia with faster and irregular beating, has…

数据分析、统计与概率 · 物理学 2017-09-27 Stefania Scarsoglio , Fabio Cazzato , Luca Ridolfi

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

定量方法 · 定量生物学 2024-02-16 Justen R Geddes , Amanda Randles