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Binding and unbinding of ligands to specific sites of a macromolecule are one of the most elementary molecular interactions inside the cell that embody the computational processes of biological regulations. The interaction between…

分子网络 · 定量生物学 2011-11-10 Hidenori Kimura , Hiroyuki Okano , Reiko J. Tanaka

We investigate the thermodynamic implications of two control mechanisms of open chemical reaction networks. The first controls the concentrations of the species that are exchanged with the surroundings, while the other controls the exchange…

统计力学 · 物理学 2022-02-22 Francesco Avanzini , Massimiliano Esposito

What is really measured in dynamic calorimetric experiments is still an open question. This paper is devoted to this question, which can be usefully envisaged by means of macroscopic non-equilibrium thermodynamics. From the pioneer work of…

软凝聚态物质 · 物理学 2007-07-15 Jean-Luc Garden

In this article we consider the possibility of controlling the dynamics of nonlinear discrete systems. A new method of control is by mixing states of the system (or the functions of these states) calculated on previous steps. This approach…

混沌动力学 · 物理学 2016-08-23 D. Dmitrishin , I. M. Skrinnik , A. Stokolos

Despite the importance of non-equilibrium statistical mechanics in modern physics and related fields, the topic is often omitted from undergraduate and core-graduate curricula. Key aspects of non-equilibrium physics, however, can be…

统计力学 · 物理学 2021-11-03 Daniel M. Zuckerman , John D. Russo

We perform molecular-dynamics simulations of a molecular system in supercooled states for different values of inertia parameters to provide evidence that the long-time dynamics depends only on the equilibrium structure. This observation is…

软凝聚态物质 · 物理学 2009-11-10 S. -H. Chong , F. Sciortino

The physics of critical phenomena in a many-body system far from thermal equilibrium is an interesting and important issue to be addressed both experimentally and theoretically. The trapped cold atoms have been actively used as a clean and…

原子物理 · 物理学 2017-09-13 Geol Moon , Myoung-Sun Heo , Yonghee Kim , Heung-Ryoul Noh , Wonho Jhe

Fluctuations in the abundance of molecules in the living cell may affect its growth and well being. For regulatory molecules (e.g., signaling proteins or transcription factors), fluctuations in their expression can affect the levels of…

分子网络 · 定量生物学 2009-11-13 Erel Levine , Terence Hwa

Protein dynamics has been investigated on a wide range of time scales. Nano- and picosecond dynamics have been assigned to local fluctuations, while slower dynamics have been attributed to larger conformational changes. However, it is…

Controlling the non adiabatic dynamics of isolated quantum systems driven through a critical point is of interest in a variety of fields ranging from quantum simulation to finite-time thermodynamics. We briefly review the different methods…

强关联电子 · 物理学 2015-02-10 A. del Campo , K. Sengupta

In these lectures we give an overview of nonequilibrium stochastic systems. In particular we discuss in detail two models, the asymmetric exclusion process and a ballistic reaction model, that illustrate many general features of…

统计力学 · 物理学 2009-11-07 M. R. Evans , R. A. Blythe

We present a general and systematic theory of non-equilibrium dynamics of multi-component fluid membranes, in general, and membranes containing transmembrane proteins, in particular. Developed based on a minimal number of principles of…

软凝聚态物质 · 物理学 2009-11-10 Michael A. Lomholt , Per L. Hansen , Ling Miao

We present two simplified models of protein dynamics based on Langevin's equation of motion in a viscous medium. We explore the effect of the potential energy function's symmetry on the kinetics and thermodynamics of simulated folding. We…

统计力学 · 物理学 2009-10-28 Gabriel F. Berriz , Alexander M. Gutin , Eugene I. Shakhnovich

Stochastic thermodynamics provides a useful set of tools to analyze and constrain the behavior of far from equilibrium systems. In this paper, we report an application of ideas from stochastic thermodynamics to the problem of membrane…

软凝聚态物质 · 物理学 2019-10-25 Michael Nguyen , Suriyanarayanan Vaikuntanathan

Many-body systems relaxing to equilibrium can exhibit complex dynamics even if their steady state is trivial. At low temperatures or high densities their evolution is often dominated by steric hindrances affecting particle motion [1,2,3].…

A Hamiltonian-based model of many harmonically interacting massive particles that are subject to linear friction and coupled to heat baths at different temperatures is used to study the dynamic approach to equilibrium and non-equilibrium…

统计力学 · 物理学 2020-09-17 Roland R. Netz

We show that, in nonequilibrium systems with small heat flows, there is a time-scale dependent effective temperature which plays the same role as the thermodynamical temperature, in that it controls the direction of heat flows and acts as a…

无序系统与神经网络 · 物理学 2009-10-28 Leticia F. Cugliandolo , Jorge Kurchan , Luca Peliti

Work fluctuation and total entropy production play crucial roles in small thermodynamic systems subject to large thermal fluctuations. We investigate a trade-off relation between them in a nonequilibrium situation in which a system starts…

统计力学 · 物理学 2016-12-15 Ken Funo , Tomohiro Shitara , Masahito Ueda

We describe a novel coarse-grained simulation method for modelling the dynamics of globular macromolecules, such as proteins. The macromolecule is treated as a continuum that is subject to thermal fluctuations. The model includes a…

计算物理 · 物理学 2015-06-11 Robin Oliver , Daniel J. Read , Oliver G. Harlen , Sarah A. Harris

Stochastic thermodynamics is formulated under the assumption of perfect knowledge of all thermodynamic parameters. However, in any real-world experiment, there is non-zero uncertainty about the precise value of temperatures, chemical…

统计力学 · 物理学 2024-01-11 Jan Korbel , David H. Wolpert
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