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Test experiments of hybridization in DNA microarrays show systematic deviations from the equilibrium isotherms. We argue that these deviations are due to the presence of a partially hybridized long-lived state, which we include in a kinetic…

生物大分子 · 定量生物学 2010-06-16 J. Hooyberghs , M. Baiesi , A. Ferrantini , E. Carlon

We develop a simple model to study the effects of an applied force on the melting of a double stranded DNA (dsDNA). Using this model, we could study the stretching, unzipping, rupture and slippage like transition in a dsDNA. We show that in…

软凝聚态物质 · 物理学 2015-05-14 Amit Raj Singh , D. Giri , S. Kumar

The liquid-liquid phase separation of biomolecules is an important process for intracellular organization. Biomolecular sequence combinatorics leads to a large variety of proteins and nucleic acids which can interact to form a diversity of…

软凝聚态物质 · 物理学 2025-08-27 Aria S. Chaderjian , Sam Wilken , Omar A. Saleh

We consider simulations of Wigner crystals interacting with random quenched disorder in the presence of thermal fluctuations. When quenched disorder is absent, there is a well defined melting temperature determined by the proliferation of…

介观与纳米尺度物理 · 物理学 2024-04-23 C. Reichhardt , C. J. O. Reichhardt

Interaction of DNA-silver nanoparticles (AgNPs) complexes with H3O+, Cu2+ and Cl- has been studied by spectro-photometric, spectro-fluorimetric and differential scanning micro calorimetric methods. It is shown that DNA is a catalyst in…

Gold nanoparticle assemblies show a strong plasmonic response due to the combined effects of the individual nanoparticles' plasmon modes. Increasing the number of nanoparticles in structured assemblies leads to significant shifts in the…

光学 · 物理学 2022-07-13 Aditya K. Sahu , Satyabrata Raj

We study numerically the mechanical stability and elasticity properties of duplex DNA molecules within the frame of a network model incorporating microscopic degrees of freedom related with the arrangement of the base pairs. We pay special…

斑图形成与孤子 · 物理学 2015-06-26 D. Hennig , J. F. R. Archilla

Base-pockets (non-complementary base-pairs) in a double-stranded DNA play a crucial role in biological processes. Because of thermal fluctuations, it can lower the stability of DNA, whereas, in case of DNA aptamer, small molecules e.g.…

软凝聚态物质 · 物理学 2015-11-23 Rakesh Kumar Mishra , Shesh Nath , Sanjay Kumar

This work explores the enhancement of ionization clusters around a gold nanoparticle (NP), indicative of the induction of DNA lesions, a potential trigger for cell-death. Monte Carlo track structure simulations were performed to determine…

医学物理 · 物理学 2024-03-08 Leo Thomas , Miriam Schwarze , Hans Rabus

The optical response of materials based on gold nanoparticle assemblies depends on many parameters regarding both material morphology and light excitation characteristics. In this paper, the interplay between the optical and thermal…

光学 · 物理学 2008-12-18 Bruno Palpant , Yannick Guillet , Majid Rashidi-Huyeh , Dominique Prot

Light-assisted micro-nanoscale temperature control in complex nanoparticle network attracts lots of research interests. Many efforts have been put on the optical properties of the nanoparticle networks and only a few investigations on its…

光学 · 物理学 2022-06-28 Minggang Luo , Junming Zhao , Linhua Liu , Mauro Antezza

We expose the theoretical mechanisms underlying disorder-induced nematicity in systems exhibiting strong fluctuations or ordering in the nematic channel. Our analysis consists of a symmetry-based Ginzburg-Landau approach and associated…

超导电性 · 物理学 2019-08-23 Daniel Steffensen , Panagiotis Kotetes , Indranil Paul , Brian M. Andersen

The proper design of DNA sequences allows for the formation of well defined supramolecular units with controlled interactions via a consecution of self-assembling processes. Here, we benefit from the controlled DNA self-assembly to…

软凝聚态物质 · 物理学 2018-02-14 Javier Fernandez-Castanon , Francesca Bomboi , Francesco Sciortino

Diblock copolymers by virtue of the chemical dissimilarity between the constituting blocks exhibit microphase separation in the melt state. The phase separated melt can successfully be exploited to control the morphology of the final semi…

软凝聚态物质 · 物理学 2018-02-19 Chitrita Kundu , Nikhil S. Joshi , Ashok Kumar Dasmahapatra

We investigate the impact of nanoparticles (NP) on the fragility and cooperative string-like motion in a model glass-forming polymer melt by molecular dynamics simulation. The NP cause significant changes to both the fragility and the…

软凝聚态物质 · 物理学 2015-05-27 Francis W. Starr , Jack F. Douglas

DNA nanocompartment is a typical DNA-based machine whose function is dependent of molecular collective effect. Fundamental properties of the device have been addressed via electrochemical analysis, fluorescent microscopy, and atomic force…

生物物理 · 物理学 2009-11-11 Song Chang , Youdong Mao , Zhengwei Xie , Chunxiong Luo , Qi Ouyang

The possibility of prescribing local interactions between nano- and microscopic components that direct them to assemble in a predictable fashion is a central goal of nanotechnology research. In this article we advance a new paradigm in…

DNA-driven self-assembly enables precise positioning of the colloidal nanoparticles owing to specific Watson-Crick interactions. Another important feature of this self-assembly method is its reversibility by controlling the temperature of…

应用物理 · 物理学 2021-05-05 Zeynep Şenel , Kutay İçöz , Talha Erdem

We investigate the crystallization of crosslinked and entangled polymers under external deformation using a coarse-grained poly(vinyl alcohol) (CG-PVA) model and molecular dynamics simulations. Following uniaxial deformation, the systems…

软凝聚态物质 · 物理学 2026-01-19 Atmika Bhardwaj , Huzaifa Shabbir , Jens-Uwe Sommer , Marco Werner

The influence of the orientation of gold nanorods in different assemblies has been investigated using the Finite Difference Time Domain (FDTD) simulation method. To understand the relative orientation, we vary the size and angle in dimer…

光学 · 物理学 2022-01-25 Aditya K. Sahu , Satyabrata Raj