相关论文: An exactly solved model of biological evolution

We investigate the evolutionary dynamics of a finite population of RNA sequences adapting to a neutral fitness landscape. Despite the lack of differential fitness between viable sequences, we observe typical properties of adaptive…

We consider quantum quench in large-N singlet sector quantum mechanics of a single hermitian matrix in the double scaling limit. The time dependent parameter is the self-coupling of the matrix. We find exact classical solutions of the…

We study a class of evolution models, where the breeding process involves an arbitrary exchangeable process, allowing for mutations to appear. The population size $n$ is fixed, hence after breeding, selection is applied. Individuals are…

Schroedinger bound-state problem in D dimensions is considered for a set of central polynomial potentials (containing 2q coupling constants). Its polynomial (harmonic-oscillator-like, quasi-exact, terminating) bound-state solutions of…

A quasispecies evolving on a fitness landscape with a single peak of fluctuating height is studied. In the approximation that back mutations can be ignored, the rate equations can be solved analytically. It is shown that the error threshold…

We study a multi-type Ehrenfest process modeled as a finite quasi-birth-death (QBD) process. We assume that the transitions are allowed only to the two adjacent levels of the same phase and are characterized by linear rates. The crucial…

Models for viral populations with high replication error rates (such as RNA viruses) rely on the quasispecies concept, in which mutational pressure beyond the so-called "Error Threshold" leads to a loss of essential genetic information and…

The quasispecies theory is studied for dynamic replication landscapes. A meaningful asymptotic quasispecies is defined for periodic time dependencies. The quasispecies' composition is constantly changing over the oscillation period. The…

In the theoretical biology framework one fundamental problem is the so-called error catastrophe in Darwinian evolution models. We reexamine Eigen's fundamental equations by mapping them into a polymer depinning transition problem in a…

We consider a class of birth-and-death processes describing a population made of $d$ sub-populations of different types which interact with one another. The state space is $\mathbb{Z}_+^d$ (unbounded). We assume that the population goes…

We analyze nonlinear degenerate coupled PDE-PDE and PDE-ODE systems that arise, for example, in the modelling of biofilm growth. One of the equations, describing the evolution of a biomass density, exhibits degenerate and singular…

We investigate the fitness advantage associated with the robustness of a phenotype against deleterious mutations using deterministic mutation-selection models of quasispecies type equipped with a mesa shaped fitness landscape. We obtain…

We study sharp peak landscapes (SPL) of Eigen model from a new perspective about how the quasispecies distribute in the sequence space. To analyze the distribution more carefully, we bring forth two tools. One tool is the variance of…

This paper develops an analytically tractable model for determining the equilibrium distribution of mismatch repair deficient strains in unicellular populations. The approach is based on the single fitness peak (SFP) model, which has been…

Quasinormal mode (QNM) spectra of black holes exhibit two open problems [Conf. Proc. C 0405132, 145 (2004); CQG 26, 163001 (2009)]: (i) the discontinuity in highly damped QNMs between Schwarzschild and Kerr solutions as $a \to 0$, and (ii)…

We investigate approximate emergent nonabelian symmetry in a class of weakly first order `deconfined' phase transitions using Monte Carlo simulations and a renormalization group analysis. We study a transition in a 3D classical loop model…

We consider the level-sets of continuous Gaussian fields on $\mathbb{R}^d$ above a certain level $-\ell\in \mathbb{R}$, which defines a percolation model as $\ell$ varies. We assume that the covariance kernel satisfies certain regularity,…

The divergence in the interaction term of the Calogero model can be prevented introducing a cutoff length parameter, this modification leads to a quasi-exactly solvable model whose eigenfunctions can be written in terms of Heun's…

Computing many eigenpairs of the Schr{\"o}dinger operator presents a computational bottleneck in large-scale quantum simulations due to the global communication overhead of explicit orthogonalization. To address this issue, we propose a…

This work addresses the problem of (global) maximal regularity for quasilinear evolution equations with sublinear gradient growth and right-hand side in Lebesgue spaces, complemented with Neumann boundary conditions. The proof relies on a…