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Microscopic biological systems operate far from equilibrium, are subject to strong fluctuations, and are composed of many coupled components with interactions varying in nature and strength. Researchers are actively investigating the…

统计力学 · 物理学 2023-12-25 Emma Lathouwers , David A. Sivak

In this paper we investigate the use of path-integral formalism and the concepts of entropy and traffic in the context of molecular motors. We show that together with time-reversal symmetry breaking arguments one can find bounds on…

统计力学 · 物理学 2015-05-13 Eliran Boksenbojm , Bram Wynants

A hopping model for molecular motors is presented consisting of a state with asymmetric hopping rates with period 2 and a state with uniform hopping rates. State changes lead to a stationary unidirectional current of a particle. The current…

统计力学 · 物理学 2015-06-25 H. Ambaye , K. W. Kehr

Comprehensive and predictive simulation of coupled reaction networks has long been a goal of biology and other fields. Currently, metabolic network models that utilize enzyme mass action kinetics have predictive power but are limited in…

分子网络 · 定量生物学 2015-12-07 William R. Cannon , Scott E. Baker

A cyclically operating chemical engine is considered that converts chemical energy into mechanical work. The working fluid is a gas of finite-sized spherical particles interacting through elastic hard collisions. For a generic transport law…

A numerical molecular dynamics experiment measuring the two-time correlation function of the transversal velocity field in the homogeneous cooling state of a granular gas is reported. By measuring the decay rate and the amplitude of the…

统计力学 · 物理学 2009-11-13 J. J. Brey , M. I. Garcia de Soria , P. Maynar

Many applications of contemporary science involve multiscale dynamics, which are typically characterized by the time and space scale separation of patterns of motion, with fewer slowly evolving variables and much larger set of faster…

动力系统 · 数学 2016-04-08 Rafail V. Abramov

We propose a stochastic model for intracellular transport processes associated with the activity of molecular motors. This out-of-equilibrium model, based on a generalized Langevin equation, considers a particle immersed in a viscoelastic…

生物物理 · 物理学 2009-04-15 L. Bruno , M. A. Despósito

The mathematical formulation of the model for molecular movement of single motor proteins driven by cyclic biochemical reactions in an aqueous environment leads to a drifted Brownian motion characterized by coupled diffusion equations. In…

统计力学 · 物理学 2007-05-23 Hong Qian

We show that the correlated stochastic fluctuation of the friction coefficient can give rise to long-range directional motion of a particle undergoing Brownian random walk in a constant periodic energy potential landscape. The occurrence of…

软凝聚态物质 · 物理学 2009-11-07 Lorenzo Marrucci , Domenico Paparo , Markus Kreuzer

Active transport such as fluid flow is sought in molecular communication to extend coverage, improve reliability, and mitigate interference. Flow models are often over-simplified, assuming one-dimensional diffusion with constant drift.…

新兴技术 · 计算机科学 2024-10-30 Wayan Wicke , Tobias Schwering , Arman Ahmadzadeh , Vahid Jamali , Adam Noel , Robert Schober

The equations of motion for the density modes of a fluid, derived from Newton's equations, are written as a linear generalized Langevin equation. The constraint imposed by the fluctuation-dissipation theorem is used to derive an exact form…

软凝聚态物质 · 物理学 2009-11-07 E. Zaccarelli , G. Foffi , F. Sciortino , P. Tartaglia , K. A. Dawson

We study the efficiency fluctuations of a stochastic heat engine made of $N$ interacting unicyclic machines and undergoing a phase transition in the macroscopic limit. Depending on $N$ and on the observation time, the machine can explore…

统计力学 · 物理学 2020-07-01 Hadrien Vroylandt , Massimiliano Esposito , Gatien Verley

Theoretical and experimental studies have shown that the fluctuations of in vivo systems break the fluctuation-dissipation theorem. One can thus ask what information is contained in the correlation functions of protein concentrations and…

化学物理 · 物理学 2016-08-24 Hélène Berthoumieux

We study the stochastic energetic exchanges in quantum heat engines. Due to microreversibility, these obey a fluctuation relation, called the heat engine fluctuation relation, which implies the Carnot bound: no machine can have an…

量子物理 · 物理学 2015-03-24 Michele Campisi , Jukka Pekola , Rosario Fazio

A recent mode coupling theory of higher-order correlation functions is tested on a simple hard-sphere fluid system at intermediate densities. Multi-point and multi-time correlation functions of the densities of conserved variables are…

统计力学 · 物理学 2009-11-07 Ramses van Zon , Jeremy Schofield

We derive the probability distribution of the efficiency of a quantum Otto engine. We explicitly compute the quantum efficiency statistics for an analytically solvable two-level engine. We analyze the occurrence of values of the stochastic…

量子物理 · 物理学 2020-09-16 Tobias Denzler , Eric Lutz

Analytical formulas for effective drift, diffusivity, run times, and run lengths are derived for an intracellular transport system consisting of a cargo attached to two cooperative but not identical molecular motors (for example, kinesin-1…

亚细胞过程 · 定量生物学 2021-01-22 Joseph J. Klobusicky , John Fricks , Peter R. Kramer

A nanoscale-sized Stirling engine with an atomistic working fluid has been modeled using molecular dynamics simulation. The design includes heat exchangers based on thermostats, pistons attached to a flywheel under load, and a regenerator.…

计算物理 · 物理学 2009-05-03 D. C. Rapaport

Multiscale dynamics are ubiquitous in applications of modern science. Because of time scale separation between relatively small set of slowly evolving variables and (typically) much larger set of rapidly changing variables, direct numerical…

动力系统 · 数学 2016-04-08 Rafail V. Abramov