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Two recent topics on a formal thermodynamic analogy of intracellular diffusivity fluctuations observed experimentally in normal/anomalous diffusion are reported. Not only the analogs of the quantity of heat and work as well as the internal…

统计力学 · 物理学 2026-04-22 Yuichi Itto

The thermodynamic uncertainty relation provides an inequality relating any mean current, the associated dispersion and the entropy production rate for arbitrary non-equilibrium steady states. Applying it here to a general model of a…

统计力学 · 物理学 2017-01-05 Patrick Pietzonka , Andre C. Barato , Udo Seifert

Collisional Brownian engines have attracted significant attention due to their simplicity, experimental accessibility, and amenability to exact analytical solutions. While previous research has predominantly focused on optimizing mean…

统计力学 · 物理学 2025-11-11 Gustavo A. L. Forão , Fernando S. Filho , Pedro V. Paraguassú

The stochastic efficiency of effusion as a thermal engine is investigated within the framework of stochastic thermodynamics. Explicit results are obtained for the probability distribution of the efficiency both at finite times and in the…

统计力学 · 物理学 2015-02-10 Karel Proesmans , Bart Cleuren , Christian Van Den Broeck

Brownian particles interacting sequentially with distinct temperatures and driving forces at each stroke have been tackled as a reliable alternative for the construction of engine setups. However they can behave very inefficiently depending…

统计力学 · 物理学 2022-12-28 Iago N. Mamede , Angel L. L. Stable , C. E. Fiore

Dynamic properties of molecular motors that fuel their motion by actively interacting with underlying molecular tracks are studied theoretically via discrete-state stochastic ``burnt-bridge'' models. The transport of the particles is viewed…

软凝聚态物质 · 物理学 2009-11-13 Maxim N. Artyomov , Alexander Yu. Morozov , Ekaterina Pronina , Anatoly B. Kolomeisky

We derive a universal bound on generalized currents in Langevin systems in terms of the mean-square fluctuations of the current and the total entropy production. This bound generalizes a relation previously found by Barato et al. to…

统计力学 · 物理学 2018-06-29 Andreas Dechant , Shin-ichi Sasa

Living systems at the molecular scale are composed of many constituents with strong and heterogeneous interactions, operating far from equilibrium, and subject to strong fluctuations. These conditions pose significant challenges to…

统计力学 · 物理学 2023-04-11 Emma Lathouwers , Joseph N. E. Lucero , David A. Sivak

In living cells, molecular motors convert chemical energy into mechanical work. Its thermodynamic energy efficiency, i.e. the ratio of output mechanical work to input chemical energy, is usually high. However, using two-state models, we…

生物物理 · 物理学 2015-03-06 Yunxin Zhang

Three problems in the statistical mechanics of models for an assembly of molecular motors interacting with cytoskeletal filaments are reviewed. First, a description of the hydrodynamical behaviour of density-density correlations in…

统计力学 · 物理学 2009-11-11 Gautam I. Menon

We study a discrete stochastic model of a molecular motor. This discrete model can be viewed as a \emph{minimal} ratchet model. We extend our previous work on this model, by further investigating the constraints imposed by the Fluctuation…

统计力学 · 物理学 2009-11-13 D. Lacoste , A. W. C. Lau , K. Mallick

The efficiency at maximum power (EMP) for tight-coupling molecular motors is investigated within the framework of irreversible thermodynamics. It is found that the EMP depends merely on the constitutive relation between the thermodynamic…

统计力学 · 物理学 2013-12-13 Z. C. Tu

Mechanochemical coupling was studied for two different types of myosin motors in cells: myosin V, which carries cargo over long distances by as a single molecule; and myosin II, which generates a contracting force in cooperation with other…

亚细胞过程 · 定量生物学 2009-11-13 Masatoshi Nishikawa , Hiroaki Takagi , Atsuko H. Iwane , Toshio Yanagida

We use stochastic computer simulations to study the transport of a spherical cargo particle along a microtubule-like track on a planar substrate by several kinesin-like processive motors. Our newly developed adhesive motor dynamics…

亚细胞过程 · 定量生物学 2010-02-24 Christian B. Korn , Stefan Klumpp , Reinhard Lipowsky , Ulrich S. Schwarz

We investigate the model of "reversible ratchet" with interacting particles, introduced by us earlier [Europhys. Lett. 84, 50009 (2008)]. We further clarify the effect of efficiency enhancement due to interaction and show that it is of…

统计力学 · 物理学 2015-03-19 Frantisek Slanina

We introduce a scheme for deriving an optimally-parametrised Langevin dynamics of few collective variables from data generated in molecular dynamics simulations. The drift and the position-dependent diffusion profiles governing the Langevin…

统计力学 · 物理学 2008-08-22 Cristian Micheletti , Giovanni Bussi , Alessandro Laio

Molecular motors are in charge of almost every process in the life cycle of cells, such as protein synthesis, DNA replication, and cell locomotion, hence being of crucial importance for understanding the cellular dynamics. However, given…

统计力学 · 物理学 2025-09-05 Adrián Nadal-Rosa , Gonzalo Manzano

This review is focused on the application of specific fluctuation relations, such as the Gallavotti-Cohen relation, to ratchet models of a molecular motor. A special emphasis is placed on two-states models such as the flashing ratchet…

统计力学 · 物理学 2011-03-02 D. Lacoste , K. Mallick

Single-molecule experiments have found near-perfect thermodynamic efficiency in the rotary motor F1-ATP synthase. To help elucidate the principles underlying nonequilibrium energetic efficiency in such stochastic machines, we investigate…

统计力学 · 物理学 2019-09-05 Joseph N. E. Lucero , Aliakbar Mehdizadeh , David A. Sivak

We consider a molecular machine described as a Brownian particle diffusing in a tilted periodic potential. We evaluate the absorbed and released power of the machine as a function of the applied molecular and chemical forces, by using the…

统计力学 · 物理学 2012-03-23 N. Golubeva , A. Imparato , L. Peliti