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相关论文: Anomalous Dynamics of Forced Translocation

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We investigate polymer translocation through a nanopore under a pulling force using Langevin dynamics simulations. We concentrate on the influence of the chain length $N$ and the pulling force $F$ on the translocation time $\tau$. The…

软凝聚态物质 · 物理学 2007-06-27 Ilkka Huopaniemi , Kaifu luo , Tapio Ala-Nissila , See-Chen Ying

We study the passage times of a translocating polymer of length $N$ in three dimensions, while it is pulled through a narrow pore with a constant force $F$ applied to one end of the polymer. At small to moderate forces, satisfying the…

软凝聚态物质 · 物理学 2008-02-14 Debabrata Panja , Gerard T. Barkema

We study translocation of semiflexible polymers driven by force $f_d$ inside a nanometer-scale pore using our three-dimensional Langevin dynamics model. We show that the translocation time $\tau$ increases with increasing bending rigidity…

生物物理 · 物理学 2018-06-27 Pauli M. Suhonen , Riku P. Linna

We investigate the dynamics of polymer translocation through a nanopore using two-dimensional Langevin dynamics simulations. In the absence of external driving force, we consider a polymer which is initially placed in the middle of the pore…

软凝聚态物质 · 物理学 2007-05-23 Ilkka Huopaniemi , Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying

We present event distributions for the polymer translocation obtained by extensive Langevin dynamics simulations. Such distributions have not been reported previously and they provide new understanding of the stochastic characteristics of…

软凝聚态物质 · 物理学 2012-04-13 R. P. Linna , K. Kaski

In forced polymer translocation, the average translocation time, $\tau$, scales with respect to pore force, $f$, and polymer length, $N$, as $\tau \sim f^{-1} N^{\beta}$. We demonstrate that an artifact in Metropolis Monte Carlo method…

生物物理 · 物理学 2009-11-13 V. V. Lehtola , R. P. Linna , K. Kaski

Monte Carlo (MC) simulations are used to study the dynamics of polymer translocation through a nanopore in the limit where the translocation rate is sufficiently slow that the polymer maintains a state of conformational quasi-equilibrium.…

软凝聚态物质 · 物理学 2015-06-12 James M. Polson , Anthony C. M. McCaffrey

Theoretical derivation and numerical confirmation are provided for the scaling of pore-blockade times as $N^{2+\nu}$ for unbiased translocation in two and three dimensions, with $N$ as the polymer length and $\nu$ as the Flory exponent of…

软凝聚态物质 · 物理学 2010-02-12 Debabrata Panja , Gerard T. Barkema

We study the translocation of a flexible polymer through extended patterned pores using molecular dynamics (MD) simulations. We consider cylindrical and conical pore geometries that can be controlled by the angle of the pore apex $\alpha$.…

软凝聚态物质 · 物理学 2026-02-11 Andri Sharma , Abhishek Chaudhuri , Rajeev Kapri

Using analytical techniques and Langevin dynamics simulations, we investigate the dynamics of polymer translocation through a nanochannel embedded in two dimensions under an applied external field. We examine the translocation time for…

软凝聚态物质 · 物理学 2012-03-26 Huaisong Yong , Yilin Wang , Shichen Yuan , Bi Xu , Kaifu Luo

We employ 3D Langevin Dynamics simulations to study the dynamics of polymer chains translocating through a nanopore in presence of asymmetric solvent conditions. Initially a large fraction ($>$ 50%) of the chain is placed at the…

软凝聚态物质 · 物理学 2010-06-09 Christopher Lorscher , Tapio Ala-Nissila , Aniket Bhattacharya

Using Langevin dynamics simulations in three dimensions (3D), we investigate the dynamics of polymer translocation into the regions between two parallel plane walls with separation $R$ under a driving force $F$, respectively. Compared with…

软凝聚态物质 · 物理学 2010-08-18 Kaifu Luo , Ralf Metzler

The transport of biomolecules across a cell membrane is an important phenomena that plays a pivotal role in the functioning of biological cells. In this paper, we investigate such processes by modeling the translocation of polymers through…

软凝聚态物质 · 物理学 2022-11-01 Andri Sharma

Polymer translocation has long been a topic of interest in the field of biological physics given its relevance in both biological (protein and DNA/RNA translocation through nuclear and cell membranes) and technological processes (nanopore…

软凝聚态物质 · 物理学 2023-09-11 Alejandro Sainz-Agost , Fernando Falo , Alessandro Fiasconaro

Polymer translocation in three dimensions out of planar confinements is studied in this paper. Three membranes are located at $z=-h$, $z=0$ and $z=h_1$. These membranes are impenetrable, except for the middle one at $z=0$, which has a…

软凝聚态物质 · 物理学 2008-01-29 Debabrata Panja , Gerard T. Barkema , Robin C. Ball

We employ a three-dimensional molecular dynamics to simulate translocation of a polymer through a nanopore driven by an external force. The translocation is investigated for different three pore diameter and two different external forces.…

计算物理 · 物理学 2019-12-03 Mohammadreza Niknam Hamidabad , Rouhollah Haji Abdolvahab

The motion of polymers with inhomogeneous structure through nanopores is discussed theoretically. Specifically, we consider the translocation dynamics of polymers consisting of double-stranded and single-stranded blocks. Since only the…

统计力学 · 物理学 2009-11-11 Stanislav Kotsev , Anatoly B. Kolomeisky

DNA translocation through nanopores is one of the most promising strategies for the next-generation sequencing technologies. Most part of experimental and numerical works has focused on polymer translocation biased by electrophoresis, where…

软凝聚态物质 · 物理学 2018-02-07 Timothée Menais

During polymer translocation driven by e.g. voltage drop across a nanopore, the segments in the cis-side is incessantly pulled into the pore, which are then pushed out of it into the trans-side. This pulling and pushing polymer segments are…

软凝聚态物质 · 物理学 2015-06-16 Takuya Saito , Takahiro Sakaue

We study the translocation of a flexible polymer through a pore in a membrane induced by its adsorption on \trans side of the membrane. When temperature $T$ is higher than $T_c$, the adsorption-desorption transition temperature, attractive…

软凝聚态物质 · 物理学 2009-10-31 Pyeong Jun Park , Wokyung Sung