相关论文: The Complexity of Biological Ageing

Statistics of article page views is useful for measuring the impact of individual articles. Analyzing the temporal evolution of article page views, we find that article page views usually decay over time after reaching a peak, especially…

Biological age is an important sociodemographic factor in studies on academic careers (research productivity, scholarly impact, and collaboration patterns). It is assumed that the academic age, or the time elapsed from the first…

Computers have a direct impact on our lives nowadays. Human's interaction with the computer has modified with the passage of time as improvement in technology occurred the better the human computer interaction became. Today we are…

We propose a generic model of eco-systems, with a {\it hierarchical} food web structure. In our computer simulations we let the eco-system evolve continuously for so long that that we can monitor extinctions as well as speciations over…

The aging phenomena occurring in the course of cycling processes in the insertion host-guest compounds are discussed in the framework of a simple model. It takes into account two types of effects. One can be attributed to modifications of…

Nearly all cell models explicitly or implicitly deal with the biophysical constraints that must be respected for life to persist. Despite this, there is almost no systematicity in how these constraints are implemented, and we lack a…

Computing in the life sciences has undergone a transformative evolution, from early computational models in the 1950s to the applications of artificial intelligence (AI) and machine learning (ML) seen today. This paper highlights key…

Increasingly sophisticated experiments, coupled with large-scale computational models, have the potential to systematically test biological hypotheses to drive our understanding of multicellular systems. In this short review, we explore key…

How self-organized networks develop, mature and degenerate is a key question for sociotechnical, cyberphysical and biological systems with potential applications from tackling violent extremism through to neurological diseases. So far, it…

With the progressive digitalisation of a majority of services to communities and individuals, humankind is facing new challenges. While energy sources are rapidly dwindling and rigorous choices have to be made to ensure the sustainability…

Aging phenomena are examples of `non-equilibrium criticality' and can be exemplified by systems with Galilean and scaling symmetries but no time translation invariance. We realize aging holographically using a deformation of a…

We propose a scheme or procedure for doing practical calculations with generalized seniority. It reduces the total computing time by calculating and storing in advance a set of intermediate quantities, taking advantage of the memory…

With rising life expectancies around the world and an older scientific workforce than ever before, what does aging mean for individual scientists, and what do aging scientists mean for scientific progress as a whole? Here we examine how…

This paper undertakes a systematic review of relevant extant literature to consider the potential societal implications of the growth of AI in manufacturing. We analyze the extensive range of AI applications in this domain, such as…

The accelerated path of technological development, particularly at the interface between hardware and biology has been suggested as evidence for future major technological breakthroughs associated to our potential to overcome biological…

The focus on managing problems that can arise for older adults has meant that extant HCI and Ageing research has not given the concepts of 'age' and 'ageing' the explicit theoretical attention they deserve. Attending to this gap, we…

Effective multicellularity requires both cooperation and competition between constituent cells. Cooperation involves sacrificing individual fitness in favor of that of the community, but excessive cooperation makes the community susceptible…

Creating autonomous, self-supporting, self-replicating, sustainable systems is a great challenge. To some extent, understanding life means not only being able to create it from scratch, but also improving, supporting, saving it, or even…

A stochastic genetic model for biological aging is introduced bridging the gap between the bit-string Penna model and the Pletcher-Neuhauser approach. The phenomenon of exponentially increasing mortality function at intermediate ages and…

While evolution has inspired algorithmic methods of heuristic optimisation, little has been done in the way of using concepts of computation to advance our understanding of salient aspects of biological phenomena. We argue that under…