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Deformations of cell sheets during morphogenesis are driven by developmental processes such as cell division and cell shape changes. In morphoelastic shell theories of development, these processes appear as variations of the intrinsic…

软凝聚态物质 · 物理学 2021-03-03 Pierre A. Haas , Raymond E. Goldstein

Cell type (e.g. pluripotent cell, fibroblast) is the end result of many complex processes that unfold due to evolutionary, developmental, and transformational stimuli. A cell's phenotype and the discrete, a priori states that define various…

定量方法 · 定量生物学 2013-02-05 Bradly Alicea

How multicellular life forms evolved out from unicellular ones constitutes a major problem in our understanding of the evolution of our biosphere. A recent set of experiments involving yeast cell populations has shown that selection for…

种群与进化 · 定量生物学 2015-11-10 Salva Duran-Nebreda , Ricard V. Solé

Plankton constitutes the productive base of aquatic ecosystems and plays an essential role in the global carbon cycle. The impact of hydrodynamic conditions on the biological activity of plankton species can manifest in a variety of…

流体动力学 · 物理学 2021-10-06 Alice Jaccod , Stefano Berti , Enrico Calzavarini , Sergio Chibbaro

In a complex system, the individual components are neither so tightly coupled or correlated that they can all be treated as a single unit, nor so uncorrelated that they can be approximated as independent entities. Instead, patterns of…

种群与进化 · 定量生物学 2015-09-15 Blake C. Stacey

Complex spatial structure, with partially isolated subpopulations, and environment heterogeneity, such as gradients in nutrients, oxygen, and drugs, both shape the evolution of natural populations. We investigate the impact of environment…

种群与进化 · 定量生物学 2026-04-07 Cecilia Fruet , Arthur Alexandre , Alia Abbara , Claude Loverdo , Anne-Florence Bitbol

Constraints in embryonic development are thought to bias the direction of evolution by making some changes less likely, and others more likely, depending on their consequences on ontogeny. Here, we characterize the constraints acting on…

种群与进化 · 定量生物学 2012-03-08 J. Roux , M. Robinson-Rechavi

The dynamics of dense particle packings near the jamming transition is characterized by correlated particle motion. The growth of dynamical heterogeneities, or strong spatial variations in the motion of the particles constituting the…

软凝聚态物质 · 物理学 2024-09-12 Rajkumar Biswas , Anoop Mutneja , Smarajit Karmakar , Ranjini Bandyopadhyay

We explore the connection between evolution and large-deviation theory. To do so, we study evolutionary dynamics in which individuals experience mutations, reproduction, and selection using variants of the Moran model. We show that, in the…

种群与进化 · 定量生物学 2026-01-09 Sara Dal Cengio , Quentin Laurenceau , Vivien Lecomte , Charline Smadi , Julien Tailleur

We present simulations of a hard disc system and analyze the time evolution of the dynamic heterogeneities. We characterize the time evolution of slow regions and slow particles individually. The motion of slow clusters turns out to be very…

软凝聚态物质 · 物理学 2009-11-07 Burkhard Doliwa , Andreas Heuer

Macroevolutionary dynamics often display sudden, explosive surges, where systems remain relatively stable for extended periods before experiencing dramatic acceleration that frequently exceeds traditional exponential growth. This pattern is…

物理与社会 · 物理学 2026-01-23 Alessandro Bellina , Giordano De Marzo , Vittorio Loreto

As an injury heals, an embryo develops, or a carcinoma spreads, epithelial cells systematically change their shape. In each of these processes cell shape is studied extensively, whereas variation of shape from cell-to-cell is dismissed most…

In this article, we propose a general framework to study the dynamics and topology of cellular networks that capture the geometry of cell packings in two-dimensional tissues. Such epithelia undergo large-scale deformation during…

组织与器官 · 定量生物学 2017-09-08 Matthias Merkel , Raphaël Etournay , Marko Popović , Guillaume Salbreux , Suzanne Eaton , Frank Jülicher

Time series of cell size evolution in unicellular marine algae (division Haptophyta; Coccolithus lineage), covering 57 million years, are studied by a system of linear stochastic differential equations of hierarchical structure. The data…

应用统计 · 统计学 2013-01-09 Trond Reitan , Tore Schweder , Jorijntje Henderiks

A variational lattice model is proposed to define an evolution of sets from a single point (nucleation) following a criterion of "maximization" of the perimeter. At a discrete level, the evolution has a "checkerboard" structure and its…

偏微分方程分析 · 数学 2021-10-27 Andrea Braides , Giovanni Scilla , Antonio Tribuzio

Turbulence has been recognized as a factor of paramount importance for the survival or extinction of sinking phytoplankton species. However, dealing with its multiscale nature in models of coupled fluid and biological dynamics is a…

流体动力学 · 物理学 2021-12-10 Vinicius Beltram Tergolina , Enrico Calzavarini , Gilmar Mompean , Stefano Berti

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

种群与进化 · 定量生物学 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Generally, genotypes and phenotypes are expected to be spatially congruent, however, in widespread species complexes with few barriers to dispersal, multiple contact zones, and limited reproductive isolation, discordance between phenotypes…

种群与进化 · 定量生物学 2017-07-14 Rebecca B. Harris , Per Alström , Anders Ödeen , Adam D. Leaché

Inhomogeneities in deposition may lead to formation of rough surfaces, whose height fluctuations can be probed directly by scanning microscopy, or indirectly by scattering. Analytical or numerical treatments of simple growth models suggest…

凝聚态物理 · 物理学 2009-10-28 Mehran Kardar

The evolution of high-dimensional phenotypes is investigated using a statistical physics model consists of interacting spins, in which genotypes, phenotypes, and environments are represented by spin configurations, interaction matrices, and…

生物物理 · 物理学 2020-06-24 Ayaka Sakata , Kunihiko Kaneko