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The problem of natural selection in dispersal-structured populations consisting of individuals characterized by different diffusion coefficients is studied. The competition between the organisms is taken into account through the assumption…

适应与自组织系统 · 物理学 2020-05-01 E. Heinsalu , D. Navidad Maeso , M. Patriarca

A theoretical study of cell evolution is presented here. By using a toolbox containing an intracellular catalytic reaction network model and a mutation-selection process, four distinct phases of self-organization were unveiled. First, the…

生物物理 · 物理学 2022-01-26 V. Ibarra-Junquera , D. Radillo-Ochoa , C. A. Terrero-Escalante

The multifarious internal workings of organisms are difficult to reconcile with a single feature defining a state of being alive. Indeed, definitions of life rely on emergent properties (growth, capacity to evolve, agency) only symptomatic…

其他定量生物学 · 定量生物学 2023-08-16 Simon Pierce

Modelling, analysing and inferring triggering mechanisms in population reproduction is fundamental in many biological applications. It is also an active and growing research domain in mathematical biology. In this chapter, we review the…

偏微分方程分析 · 数学 2023-01-09 Marie Doumic , Marc Hoffmann

Multistability, the coexistence of multiple attractors in a dynamical system, is explored in bursting nerve cells. A modeling study is performed to show that a large class of bursting systems, as defined by a shared topology when…

神经元与认知 · 定量生物学 2010-06-29 J. P. Newman , R. J. Butera

Intracellular protein patterns govern essential cellular functions by dynamically redistributing proteins between membrane-bound and cytosolic states, conserving their total numbers. This review presents a theoretical framework for…

生物物理 · 物理学 2025-12-16 Erwin Frey , Henrik Weyer

The dynamical behavior of two types of non-equilibrium systems is discussed: $(a)$ two-dimensional cellular structures, and $(b)$ living polymers. Simple models governing their evolution are introduced and steady state distributions (cell…

凝聚态物理 · 物理学 2007-05-23 David Mukamel

A varying number of particles is one of the most relevant characteristics of systems of interest in nature and technology, ranging from the exchange of energy and matter with the surrounding environment to the change of particle number…

数学物理 · 物理学 2025-10-15 Mauricio J. del Razo , Luigi Delle Site

In multi-cellular organisms, cells differentiate into multiple types as they divide. States of these cell types, as well as their numbers, are known to be robust to external perturbations; as conceptualized by Waddington's epigenetic…

生物物理 · 物理学 2026-01-21 Davey Plugers , Kunihiko Kaneko

In apparent contradiction to competition theory, the number of known, co-existing plankton species far exceeds their explicable biodiversity - a discrepancy termed the Paradox of the Plankton. We introduce a new game-theoretic model for…

种群与进化 · 定量生物学 2020-12-14 Susanne Menden-Deuer , Julie Rowlett

Signaling molecules play an important role for many cellular functions. We investigate here a general system of two membrane reaction-diffusion equations coupled to a diffusion equation inside the cell by a Robin-type boundary condition and…

偏微分方程分析 · 数学 2015-06-16 Andreas Rätz , Matthias Röger

Deterministic many-body systems governed by simple interactions can self-organize into macroscopic patterns, and the determinants of long-time behavior are assumed to be encoded in the initial configuration. Here we show that predictability…

生物物理 · 物理学 2026-04-02 Lars Koopmans , Elinor M. Kay , Hyun Youk

Network of nonlinear dynamical elements often show clustering of synchronization by chaotic instability. Relevance of the clustering to ecological, immune, neural, and cellular networks is discussed, with the emphasis of partially ordered…

chao-dyn · 物理学 2009-10-22 Kunihiko Kaneko

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

生物物理 · 物理学 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

In this expository and resources chapter we review selected aspects of the mathematics of dynamical systems, stability, and chaos, within a historical framework that draws together two threads of its early development: celestial mechanics…

混沌动力学 · 物理学 2016-11-09 R. Ball , P. Holmes

Multistability is a phenomenon prevalent in many natural systems. In climate, for example, it allows the possibility of irreversible consequences on planetary scale as a result of climate change. Indeed, a climate ``tipping element'' is a…

大气与海洋物理 · 物理学 2026-04-14 George Datseris , Johannes Lohmann , Oisín Hamilton , Jacob Haqq-Misra

The cell cycle duration is a variable cellular phenotype that underlies long-term population growth and age structures. By analyzing the stationary solutions of a branching process with heritable cell division times, we demonstrate…

种群与进化 · 定量生物学 2021-01-04 Takashi Nozoe , Edo Kussell

Cells of the human body have nearly identical genome but exhibit very different phenotypes that allow them to carry out specific functions and react to changes in their surrounding environment. This division of labour is achieved by…

This paper is to show that most discrete models used for population dynamics in ecology are inherently pathological that their predications cannot be independently verified by experiments because they violate a fundamental principle of…

种群与进化 · 定量生物学 2007-05-23 Bo Deng

To unveil the logic of cell from a level of chemical reaction dynamics, we need to clarify how ensemble of chemicals can autonomously produce the set of chemical, without assuming a specific external control echanism. A cell consists of a…

分子网络 · 定量生物学 2007-05-23 Kunihiko Kaneko