相关论文: Statin Recommendations among US Adults with the 20…
There have been increased concerns that the use of statins, one of the most commonly prescribed drugs for treating coronary artery disease, is potentially associated with the increased risk of new-onset type II diabetes (T2D). Nevertheless,…
Physical activity (PA) is widely recognized as protective against mental distress, yet whether this benefit varies systematically across population subgroups remains poorly understood. Using pooled data from ten consecutive annual waves of…
We consider the problem of individual-specific medication level recommendation (initiation, removal, increase, or decrease) for asthma sufferers. Asthma is one of the most common chronic diseases in both adults and children, affecting 8% of…
The regression discontinuity (RD) design is a quasi-experimental design that estimates the causal effects of a treatment by exploiting naturally occurring treatment rules. It can be applied in any context where a particular treatment or…
Background: Technology has provided a new way of life for adolescents. Strategies aimed at improving health behaviors through digital platforms can offer promising results. However, since peers can modify behaviors related to food and…
Background: Higher endogenous testosterone levels are associated with reduced chronic disease risk and mortality. Since the mid-20th century, there have been significant changes in dietary patterns, and men's testosterone levels have…
Hypertension is a global health concern with an increasing prevalence, underscoring the need for effective monitoring and analysis of blood pressure (BP) dynamics. We analyzed a substantial BP dataset comprising 75,636,128 records from…
Progression to dialysis or end-stage renal disease is a rare but clinically important outcome. Clinicians need evidence on how medication exposures influence downstream risk. We constructed a fixed-window EHR cohort (90-day observation,…
Despite the well-acknowledged benefits of physical activity for type 2 diabetes (T2D) prevention, the literature surprisingly lacks validated models able to predict the long-term benefits of exercise on T2D progression and support…
We will study the impact of adolescent sports participation on early-adulthood health using longitudinal data from the National Study of Youth and Religion. We focus on two primary outcomes measured at ages 23--28 -- self-rated health and…
As witnessed in the past year, where the world was brought to the ground by a pandemic, fighting Life-threatening diseases have found greater focus than ever. The first step in fighting a disease is to diagnose it at the right time.…
Propensity score weighting approaches have been widely implemented in clinical research to estimate the effects of a treatment or exposure while mitigating the risk of confounding in the absence of random assignment. In practice, when…
Background: Cannabis use disorder (CUD) is a growing public health problem. Early identification of adolescents and young adults at risk of developing CUD in the future may help stem this trend. A logistic regression model fitted using a…
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in…
Diabetes has affected over 246 million people worldwide with a majority of them being women. According to the WHO report, by 2025 this number is expected to rise to over 380 million. The disease has been named the fifth deadliest disease in…
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects 30-40% of US adults and is the most common chronic liver disease. Although often asymptomatic, progression can lead to cirrhosis. The objective of the…
Cardiovascular diseases are the leading cause of death. Increased levels of plasma cholesterol are consistently associated with an increased risk of cardiovascular disease. As a result, it is imperative that studies are conducted to…
Disease progression varies with age and is influenced by underlying genetic, biochemical, and hormonal etiologies, suggesting the need for tailored monitoring, care, and medication beyond standard clinical guidelines. Specifically, in…
Vicodin is the most commonly prescribed pain reliever in the United States. Research indicates that there are two million people who are currently abusing Vicodin, and the majority of those who abuse Vicodin were initially exposed to it via…
Background:Chronic kidney disease is one of the most prevalent non-communicable health issues globally, and high body mass index plays a significant role in the onset and progression of chronic kidney disease. Methods: Data on the disease…