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Background: Recent genome-wide association studies (GWAS) have identified a large number of genetic risk factors for schizophrenia (SCZ) featuring ion channels and calcium transporters. For some of these risk factors, independent prior…

The relation between spontaneous and stimulated brain activity is a fundamental question in neuroscience, which has received wide attention in experimental studies. Recently, it has been suggested that the evoked response to external…

无序系统与神经网络 · 物理学 2023-06-16 M. K. Nandi , A. De Candia , A. Sarracino , H. J. Herrmann , L. de Arcangelis

This study introduces a novel auditory neuronal network model that integrates speech signal input, cochlear processing, and a cortical excitatory-inhibitory (E-I) balanced network. Our findings reveal that increasing noise intensity…

神经元与认知 · 定量生物学 2025-12-09 Duoyu Feng , Jiajia Li

It has been hypothesized that Gamma cortical oscillations play important roles in numerous cognitive processes and may involve psychiatric conditions including anxiety, schizophrenia, and autism. Gamma rhythms are commonly observed in many…

神经元与认知 · 定量生物学 2021-03-11 Fereshteh Arab , Sareh Rostami , Mohammad Dehghani-Habibabadi , Vahid Salari , Mir-Shahram Safari

During slow-wave sleep, the brain produces traveling waves of slow oscillations (SOs; $\leq 2$ Hz), characterized by the propagation of alternating high- and low-activity states. The question of internal mechanisms that modulate traveling…

适应与自组织系统 · 物理学 2025-10-16 Ronja Strömsdörfer , Klaus Obermayer

This study investigates the speech articulatory coordination in schizophrenia subjects exhibiting strong positive symptoms (e.g. hallucinations and delusions), using two distinct channel-delay correlation methods. We show that the…

音频与语音处理 · 电气工程与系统科学 2023-05-18 Yashish M. Siriwardena , Chris Kitchen , Deanna L. Kelly , Carol Espy-Wilson

Slow waves (SWs) are spatio-temporal patterns of cortical activity that occur both during natural sleep and anesthesia and are preserved across species. Even though electrophysiological recordings have been largely used to characterize…

In the field of neuroscience, Brain activity analysis is always considered as an important area. Schizophrenia(Sz) is a brain disorder that severely affects the thinking, behaviour, and feelings of people all around the world.…

信号处理 · 电气工程与系统科学 2021-11-23 Geetanjali Sharma , Amit M. Joshi

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

神经元与认知 · 定量生物学 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

Schizophrenia (SZ) is a mental disorder whereby due to the secretion of specific chemicals in the brain, the function of some brain regions is out of balance, leading to the lack of coordination between thoughts, actions, and emotions. This…

I compute the average trial-by-trial power of band-limited speech activity across epochs of multi-channel high-density electrocorticography (ECoG) recorded from multiple subjects during a consonant-vowel speaking task. I show that…

神经元与认知 · 定量生物学 2024-12-31 Eric Easthope

In this work we study the communication efficiency of a psychophysically-tuned cascade of Wilson-Cowan and Divisive Normalization layers that simulate the retina-V1 pathway. This is the first analysis of Wilson-Cowan networks in terms of…

神经元与认知 · 定量生物学 2019-07-31 Alexander Gomez-Villa , Marcelo Bertalmío , Jesús Malo

A generalized version of the Wilson-Cowan (WC) model is proposed which accounts for the evolution of the synaptic resources. Adiabatic elimination of the fast variables is performed to yield a simplified framework for the coupled…

无序系统与神经网络 · 物理学 2025-11-21 Tommaso Trabocchi , Raffaella Burioni , Lucilla de Arcangelis , Duccio Fanelli

Advances in artificial intelligence (AI) and deep learning have improved diagnostic capabilities in healthcare, yet limited interpretability continues to hinder clinical adoption. Schizophrenia, a complex disorder with diverse symptoms…

音频与语音处理 · 电气工程与系统科学 2025-11-06 Gowtham Premananth , Carol Espy-Wilson

This study investigates the speech articulatory coordination in schizophrenia subjects exhibiting strong positive symptoms (e.g.hallucinations and delusions), using a time delay embedded correlation analysis. We show that the schizophrenia…

音频与语音处理 · 电气工程与系统科学 2021-02-16 Yashish Maduwantha H. P. E. R. S , Chris Kitchen , Deanna L. Kelly , Carol Espy-Wilson

Schizophrenia (SZ) is a brain disorder leading to detached mind's normally integrated processes. Hence, the exploration of the symptoms in relation to functional connectivity (FC) had great relevance in the field. FC can be investigated on…

神经元与认知 · 定量生物学 2026-04-08 Davide Coluzzi , Giuseppe Baselli

Building upon our previous work on the Wilson-Cowan equations with distributed delays, we study the dynamic behavior in a system of two coupled Wilson-Cowan pairs. We focus in particular on understanding the mechanisms that govern the…

动力系统 · 数学 2023-07-14 Eva Kaslik , Emanuel-Attila Kokovics , Anca Radulescu

Dynamic excitatory-inhibitory (E-I) balance is a paradigmatic mechanism invoked to explain the irregular low firing activity observed in the cortex. However, we will show that the E-I balance can be at the origin of other regimes observable…

神经元与认知 · 定量生物学 2023-11-13 Hongjie Bi , Matteo Di Volo , Alessandro Torcini

The relation between spontaneous and stimulated global brain activity is a fundamental problem in the understanding of brain functions. This question is investigated both theoretically and experimentally within the context of nonequilibrium…

神经元与认知 · 定量生物学 2020-09-07 A. Sarracino , O. Arviv , O. Shriki , L. de Arcangelis

Modeling and simulating how oxygen supply shapes neuronal excitability is crucial for advancing the understanding of brain function in pathological scenarios, such as ischemia. This condition is caused by a reduced blood supply, leading to…

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