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Calcium imaging is one of the most important tools in neurophysiology as it enables the observation of neuronal activity for hundreds of cells in parallel and at single-cell resolution. In order to use the data gained with calcium imaging,…

神经元与认知 · 定量生物学 2020-04-07 Elke Kirschbaum , Alberto Bailoni , Fred A. Hamprecht

Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

计算机视觉与模式识别 · 计算机科学 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Quantitative phase microscopy (QPM) and interferometric scattering (iSCAT) microscopy are powerful label-free imaging techniques and are widely used for biomedical applications. Each method, however, possesses distinct limitations: QPM,…

光学 · 物理学 2025-03-20 Kohki Horie , Keiichiro Toda , Takuma Nakamura , Takuro Ideguchi

In recent years, a number of methods have been proposed to estimate the times at which a neuron spikes on the basis of calcium imaging data. However, quantifying the uncertainty associated with these estimated spikes remains an open…

统计方法学 · 统计学 2026-04-27 Yiqun T. Chen , Sean W. Jewell , Daniela M. Witten

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

图像与视频处理 · 电气工程与系统科学 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

Accurate detection of mitosis plays a critical role in breast cancer histopathology. Manual detection and counting of mitosis is tedious and subject to considerable inter- and intra-reader variations. Multispectral imaging is a recent…

计算机视觉与模式识别 · 计算机科学 2013-04-16 H. Irshad , A. Gouaillard , L. Roux , D. Racoceanu

The minimal invasive procedure of vertebroplasty is a surgical technique to treat compression fractures of vertebral bodies. During the treatment, liquid bone cement gets injected into the affected vertebral body and therein cures to a…

Purpose: Recent developments in hardware design enable the use of Fast Field-Cycling (FFC) techniques in MRI to exploit the different relaxation rates at very low field strength, achieving novel contrast. The method opens new avenues for in…

信号处理 · 电气工程与系统科学 2021-05-19 Markus Bödenler , Oliver Maier , Rudolf Stollberger , Lionel M. Broche , P. James Ross , Mary-Joan MacLeod , Hermann Scharfetter

Purpose: To present a computational procedure for accelerated, calibrationless magnetic resonance image (Cl-MRI) reconstruction that is fast, memory efficient, and scales to high-dimensional imaging. Theory and Methods: Cl-MRI methods can…

图像与视频处理 · 电气工程与系统科学 2021-07-23 Shen Zhao , Lee C. Potter , Rizwan Ahmad

Purpose: There is increasing interest in computed tomography (CT) image estimations from magnetic resonance (MR) images. The estimated CT images can be utilised for attenuation correction, patient positioning, and dose planning in…

统计方法学 · 统计学 2019-04-02 Fekadu L. Bayisa , Xijia Liu , Anders Garpebring , Jun Yu

CBCT images suffer from acute shading artifacts primarily due to scatter. Numerous image-domain correction algorithms have been proposed in the literature that use patient-specific planning CT images to estimate shading contributions in…

计算机视觉与模式识别 · 计算机科学 2018-01-18 Awais Ashfaq , Jonas Adler

Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…

This study presents an experimental determination of spectroscopic parameters for the less-abundant isotopologues $^{42}$CaF and $^{44}$CaF, alongside $^{40}$CaF, using high-resolution laser-induced fluorescence spectroscopy in a skimmed…

Preclinical research and organ-dedicated applications require high-resolution positron emission tomography (PET) detectors to visualize small structures and understand biological processes at a finer level of detail. Current commercial…

Clear identification of bone structures is crucial for ultrasound-guided lumbar interventions, but it can be challenging due to the complex shapes of the self-shadowing vertebra anatomy and the extensive background speckle noise from the…

图像与视频处理 · 电气工程与系统科学 2022-11-17 Baichuan Jiang , Keshuai Xu , Ahbay Moghekar , Peter Kazanzides , Emad Boctor

Thermal ablation procedures, such as high intensity focused ultrasound (HIFU) and Radiofrequency Ablation (RFA), are often used to eliminate tumors by minimally invasively heating a focal region. For this task, real-time 3D temperature…

医学物理 · 物理学 2023-01-18 Nathan Wang , Mengzhou Li , Petteri Haverinen

Virtual histology is an emerging field in biomedicine that enables three-dimensional tissue visualization using X-ray micro-computed tomography. However, the method still lacks the specificity of conventional histology, in which parts of…

Miniaturized spectrometry system is playing an essential role for materials analysis in the development of in-situ or portable sensing platforms across research and industry. However, there unavoidably exists trade-offs between the…

We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling…

计算机科学中的逻辑 · 计算机科学 2011-11-10 Pietro Liò , Emanuela Merelli , Nicola Paoletti

Vertebrae identification in arbitrary fields-of-view plays a crucial role in diagnosing spine disease. Most spine CT contain only local regions, such as the neck, chest, and abdomen. Therefore, identification should not depend on specific…

计算机视觉与模式识别 · 计算机科学 2024-01-17 Sheng Zhang , Minheng Chen , Junxian Wu , Ziyue Zhang , Tonglong Li , Cheng Xue , Youyong Kong