相关论文: Spectral micro-CT for quantitative analysis of cal…
While drastic improvements in CT technology have occurred in the past 25 years, spatial resolution is one area where progress has been limited until recently. New photon counting CT systems, are capable of much better spatial resolution…
Over the past decades, thermal ablation procedures such as high intensity focused ultrasound (HIFU) have been developed vaporize cancerous tissues in a focal area. Thermal ablation has the potential to non-invasively eliminate tumors and…
Bone marrow (BM) metabolic quantification with 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is of broad clinical significance for accurate assessment of BM at staging and follow-up, especially when immunotherapy is…
Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…
We propose a method for estimating the bone mineral density (BMD) from a plain x-ray image. Dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) provide high accuracy in diagnosing osteoporosis; however, these…
Involuntary motion during weight-bearing cone-beam computed tomography (CT) scans of the knee causes artifacts in the reconstructed volumes making them unusable for clinical diagnosis. Currently, image-based or marker-based methods are…
We present a structured matrix factorization approach to analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of the neurons, demix spatially overlapping components, and…
Photon-counting computed tomography has demonstrated significant advancements in recent years; however, micro photon-counting CT (Micro-PCCT) systems are still limited by pixel-wise detector response nonuniformity, which degrades…
Accurate assessment of burn severity at injury onset remains a major clinical challenge due to the lack of objective methods for detecting subsurface tissue damage. This limitation is critical in battlefield and mass-casualty settings,…
Osteoporosis is a skeletal disorder that leads to increased fracture risk due to decreased strength of cortical and trabecular bone. Even with state-of-the-art non-invasive assessment methods there is still a high underdiagnosis rate.…
Non-contrast computed tomography calcium scoring (CTCS) is a cost-effective imaging modality widely used to detect coronary artery calcifications. This study aimed to develop an advanced machine learning framework that utilizes quantitative…
The appearance of microcalcifications in mammograms is one of the early signs of breast cancer. So, early detection of microcalcification clusters (MCCs) in mammograms can be helpful for cancer diagnosis and better treatment of breast…
Bone segmentation is an essential step for the preoperative planning of fracture trauma surgery. The automated segmentation of fractured bone from computed tomography (CT) scans remains challenging, due to the large differences of fractures…
The incidence of vertebral fragility fracture is increased by the presence of preexisting pathologies such as metastatic disease. Computational tools could support the fracture prediction and consequently the decision of the best medical…
Quantitative phase imaging (QPI) quantifies the sample-specific optical-phase-delay enabling objective studies of optically-transparent specimens such as biological samples, but lacks chemical sensitivity limiting its application to…
Morphological features of small vessels provide invaluable information regarding underlying tissue, especially in cancerous tumors. This paper introduces methods for obtaining quantitative morphological features from microvasculature images…
Spectral CT offers enhanced material discrimination over single-energy systems and enables quantitative estimation of basis material density images. Water/iodine decomposition in contrast-enhanced CT is one of the most widespread…
Vertebral body compression fractures are reliable early signs of osteoporosis. Though these fractures are visible on Computed Tomography (CT) images, they are frequently missed by radiologists in clinical settings. Prior research on…
The potential huge advantage of spectral computed tomography (CT) is its capability to provide accuracy material identification and quantitative tissue information. This can benefit clinical applications, such as brain angiography, early…
Estimation of the covariance structure of spatial processes is of fundamental importance in spatial statistics. In the literature, several non-parametric and semi-parametric methods have been developed to estimate the covariance structure…