相关论文: Spectral micro-CT for quantitative analysis of cal…
Microcalcifications in mammogram have been mainly targeted as a reliable earliest sign of breast cancer and their early detection is vital to improve its prognosis. Since their size is very small and may be easily overlooked by the…
Purpose: The main purpose of this study was to assess the reliability of shape and heterogeneity features in both Positron Emission Tomography (PET) and low-dose Computed Tomography (CT) components of PET/CT. A secondary objective was to…
We present a scalable Bayesian framework for the analysis of confocal fluorescence spectroscopy data, addressing key limitations in traditional fluorescence correlation spectroscopy methods. Our framework captures molecular motion,…
In this paper, a novel method for edge detection of microcalcification clusters in mammogram images is presented using the concept of Fractal Dimension and Hurst co-efficient that enables to locate the microcalcifications in the mammograms.…
Recent studies have shown potential for using polarisation sensitive optical coherence tomography (PS-OCT) to study cartilage morphology, and to be potentially used as an in-vivo, non-invasive tool for detecting osteoarthritic changes.…
Purpose: Following the clinical success of 177Lu-based therapies, accurate quantification of 177Lu using radionuclide calibrators (RNCs) and SPECT/CT is gaining importance as prerequisite for accurate treatment delivery and dosimetry.…
Differentiation of breast tissues is challenging in X-ray imaging because tissues might share similar or even the same linear attenuation coefficients $\mu$. Spectral computed tomography (CT) allows for more quantitative characterization in…
Fractal analysis has been shown to be useful in image processing for characterizing shape and gray-scale complexity. The fractal feature is a compact descriptor used to give a numerical measure of the degree of irregularity of the medical…
Quantitative computed tomography (QCT) is a widely used tool for osteoporosis diagnosis and monitoring. The assessment of cortical markers like cortical bone mineral density (BMD) and thickness is a demanding task, mainly because of the…
Fluorescent calcium imaging provides a potentially powerful tool for inferring connectivity in neural circuits with up to thousands of neurons. However, a key challenge in using calcium imaging for connectivity detection is that current…
Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA), which quantifies areal bone mineral density but overlooks bone microarchitecture and surrounding soft tissues. High-resolution peripheral…
We present a novel method for characterizing mammographic findings using spectral imaging without the use of contrast agent. Within a statistical framework, suspicious findings are analyzed to determine if they are likely to be benign…
Spectral CT has shown promise for high-sensitivity quantitative imaging and material decomposition. This work presents a new device called a spatial-spectral filter (SSF) which consists of a tiled array of filter materials positioned near…
This paper proposes a novel, unsupervised super-resolution (SR) approach for performing the SR of a clinical CT into the resolution level of a micro CT ($\mu$CT). The precise non-invasive diagnosis of lung cancer typically utilizes clinical…
Determination of fundamental mechanisms of disease often hinges on histopathology visualization and quantitative image analysis. Currently, the analysis of multi-channel fluorescence tissue images is primarily achieved by manual…
Miniaturized calcium imaging is an emerging neural recording technique that has been widely used for monitoring neural activity on a large scale at a specific brain region of rats or mice. Most existing calcium-image analysis pipelines…
Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…
Accurate and timely identification of pulmonary nodules on chest X-rays can differentiate between life-saving early treatment and avoidable invasive procedures. Calcification is a definitive indicator of benign nodules and is the primary…
Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…
Tissue oxygenation and perfusion can be an indicator for organ viability during minimally invasive surgery, for example allowing real-time assessment of tissue perfusion and oxygen saturation. Multispectral imaging is an optical modality…