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White Matter Injury (WMI) is the most prevalent brain injury in the preterm neonate leading to developmental deficits. However, detecting WMI in Magnetic Resonance (MR) images of preterm neonate brains using traditional WM…

计算机视觉与模式识别 · 计算机科学 2018-07-19 Subhayan Mukherjee , Irene Cheng , Steven Miller , Jessie Guo , Vann Chau , Anup Basu

Brain tissue segmentation from multimodal MRI is a key building block of many neuroimaging analysis pipelines. Established tissue segmentation approaches have, however, not been developed to cope with large anatomical changes resulting from…

图像与视频处理 · 电气工程与系统科学 2020-11-05 Reuben Dorent , Thomas Booth , Wenqi Li , Carole H. Sudre , Sina Kafiabadi , Jorge Cardoso , Sebastien Ourselin , Tom Vercauteren

Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

图像与视频处理 · 电气工程与系统科学 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

音频与语音处理 · 电气工程与系统科学 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Accurately detecting Alzheimer's disease (AD) and predicting mini-mental state examination (MMSE) score are important tasks in elderly health by magnetic resonance imaging (MRI). Most of the previous methods on these two tasks are based on…

图像与视频处理 · 电气工程与系统科学 2023-07-10 Xu Tian , Jin Liu , Hulin Kuang , Yu Sheng , Jianxin Wang , The Alzheimer's Disease Neuroimaging Initiative

Deep learning has been recently used for the analysis of neuroimages, such as structural magnetic resonance imaging (MRI), functional MRI, and positron emission tomography (PET), and has achieved significant performance improvements over…

图像与视频处理 · 电气工程与系统科学 2020-05-12 Li Zhang , Mingliang Wang , Mingxia Liu , Daoqiang Zhang

For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

计算机视觉与模式识别 · 计算机科学 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

Motivation. While recent studies show high accuracy in the classification of Alzheimer's disease using deep neural networks, the underlying learned concepts have not been investigated. Goals. To systematically identify changes in brain…

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

计算机视觉与模式识别 · 计算机科学 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

机器学习 · 计算机科学 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

定量方法 · 定量生物学 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

人机交互 · 计算机科学 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

信号处理 · 电气工程与系统科学 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

计算机视觉与模式识别 · 计算机科学 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

Deep neural networks have led to state-of-the-art results in many medical imaging tasks including Alzheimer's disease (AD) detection based on structural magnetic resonance imaging (MRI) data. However, the network decisions are often…

定量方法 · 定量生物学 2019-08-28 Moritz Böhle , Fabian Eitel , Martin Weygandt , Kerstin Ritter

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed

Alzheimer's Disease (AD) is the world leading cause of dementia, a progressively impairing condition leading to high hospitalization rates and mortality. To optimize the diagnostic process, numerous efforts have been directed towards the…

图像与视频处理 · 电气工程与系统科学 2025-01-20 Davide Coluzzi , Valentina Bordin , Massimo Walter Rivolta , Igor Fortel , Liang Zhang , Alex Leow , Giuseppe Baselli

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders worldwide. As it progresses, it leads to the deterioration of cognitive functions. Since AD is irreversible, early diagnosis is crucial for managing its…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Mahdieh Behjat Khatooni , Mohsen Soryani