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Predicting future brain state from a baseline magnetic resonance image (MRI) is a central challenge in neuroimaging and has important implications for studying neurodegenerative diseases such as Alzheimer's disease (AD). Most existing…

计算机视觉与模式识别 · 计算机科学 2026-05-28 Ali Farki , Elaheh Moradi , Deepika Koundal , Jussi Tohka

Structural MRI and PET imaging play an important role in the diagnosis of Alzheimer's disease (AD), showing the morphological changes and glucose metabolism changes in the brain respectively. The manifestations in the brain image of some…

图像与视频处理 · 电气工程与系统科学 2023-08-11 Yanteng Zhang , Qizhi Teng , Xiaohai He , Tong Niu , Lipei Zhang , Yan Liu , Chao Ren

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

计算机视觉与模式识别 · 计算机科学 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

图像与视频处理 · 电气工程与系统科学 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This…

神经元与认知 · 定量生物学 2024-10-22 Jiwon Youn , Dong Woo Kang , Hyun Kook Lim , Mansu Kim

Alzheimer's disease (AD) leads to progressive cognitive decline, making early detection crucial for effective intervention. While deep learning models have shown high accuracy in AD diagnosis, their lack of interpretability limits clinical…

计算机视觉与模式识别 · 计算机科学 2025-06-17 Yasmine Mustafa , Mohamed Elmahallawy , Tie Luo

Early detection of Alzheimer's Disease (AD) is greatly beneficial to AD patients, leading to early treatments that lessen symptoms and alleviating financial burden of health care. As one of the leading signs of AD, language capability…

计算与语言 · 计算机科学 2025-10-17 Yangyang Li

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

计算机视觉与模式识别 · 计算机科学 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

The current state-of-the-art deep neural networks (DNNs) for Alzheimer's Disease diagnosis use different biomarker combinations to classify patients, but do not allow extracting knowledge about the interactions of biomarkers. However, to…

机器学习 · 计算机科学 2021-09-28 Raphael Ronge , Kwangsik Nho , Christian Wachinger , Sebastian Pölsterl

Alzheimer's disease (AD) is a devastating neurodegenerative condition that precedes progressive and irreversible dementia; thus, predicting its progression over time is vital for clinical diagnosis and treatment. Numerous studies have…

人工智能 · 计算机科学 2023-10-06 Seungwoo Jeong , Wonsik Jung , Junghyo Sohn , Heung-Il Suk

Longitudinal magnetic resonance imaging data is used to model trajectories of change in brain regions of interest to identify areas susceptible to atrophy in those with neurodegenerative conditions like Alzheimer's disease. Most methods for…

应用统计 · 统计学 2024-07-25 Robert Zielinski , Kun Meng , Ani Eloyan

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

图像与视频处理 · 电气工程与系统科学 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Understanding the relationship between cognition and intrinsic brain activity through purely data-driven approaches remains a significant challenge in neuroscience. Resting-state functional magnetic resonance imaging (rs-fMRI) offers a…

机器学习 · 计算机科学 2024-11-01 Yutong Gao , Vince D. Calhoun , Robyn L. Miller

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

图像与视频处理 · 电气工程与系统科学 2021-01-07 Kuo Yang , Emad A. Mohammed

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

计算机视觉与模式识别 · 计算机科学 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Localization of focal vascular lesions on brain MRI is an important component of research on the etiology of neurological disorders. However, manual annotation of lesions can be challenging, time-consuming and subject to observer bias.…

图像与视频处理 · 电气工程与系统科学 2019-07-30 Kimberlin M. H. van Wijnen , Florian Dubost , Pinar Yilmaz , M. Arfan Ikram , Wiro J. Niessen , Hieab Adams , Meike W. Vernooij , Marleen de Bruijne

Deep learning models have shown strong performance in diagnosing Alzheimer's disease (AD) using neuroimaging data, particularly 18F-FDG PET scans, with training datasets largely composed of North American cohorts such as those in the…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Hugo Massaroli , Hernan Chaves , Pilar Anania , Mauricio Farez , Emmanuel Iarussi , Viviana Siless