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The capability of cells to form surface extensions to non-locally probe the surrounding environment plays a key role in cell migration. The existing mathematical models for migration of cell populations driven by this non-local form of…

细胞行为 · 定量生物学 2025-12-24 Tommaso Lorenzi , Nadia Loy , Chiara Villa

We study the long-time behaviour of phenotype-structured models describing the evolutionary dynamics of asexual species whose phenotypic fitness landscape is characterised by multiple peaks. First we consider the case where phenotypic…

偏微分方程分析 · 数学 2020-10-28 Tommaso Lorenzi , Camille Pouchol

We propose and investigate general kinetic models %of Boltzmann type with transition probabilities that can describe the simultaneous change of multiple microscopic states of the interacting agents. These models can be applied to many…

数学物理 · 物理学 2023-02-23 Marzia Bisi , Nadia Loy

In this work, we provide an asymptotic analysis of the solutions to an elliptic integro-differential equation. This equation describes the evolutionary equilibria of a phenotypically structured population, subject to selection, mutation,…

偏微分方程分析 · 数学 2022-01-19 Alexis Léculier , Sepideh Mirrahimi

Phenotypically structured equations arise in population biology to describe the interaction of species with their environment that brings the nutrients. This interaction usually leads to selection of the fittest individuals. Models used in…

偏微分方程分析 · 数学 2015-06-18 Alexander Lorz , Benoit Perthame

Populations are heterogeneous, deviating in numerous ways. Phenotypic diversity refers to the range of traits or characteristics across a population, where for cells this could be the levels of signalling, movement and growth activity, etc.…

细胞行为 · 定量生物学 2025-04-11 Tommaso Lorenzi , Kevin J Painter , Chiara Villa

We discuss several models of the dynamics of interacting populations. The models are constructed by nonlinear differential equations and have two sets of parameters: growth rates and coefficients of interaction between populations. We…

适应与自组织系统 · 物理学 2013-07-29 Nikolay K. Vitanov , Zlatinka I. Dimitrova

In this paper, we analyze the behavior of a multi-agent system driven by the interactions of agents within a competitive environment. To achieve this, we describe the transition probabilities that underlie the system's stochastic nature. We…

多智能体系统 · 计算机科学 2024-12-23 Mohammad Daneshvar , Mandana Delavari

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

We analyze the long-term stability of a stochastic model designed to illustrate the adaptation of a population to variation in its environment. A piecewise-deterministic process modeling adaptation is coupled to a Feller logistic diffusion…

概率论 · 数学 2021-09-14 Aurélien Velleret

1) Micro-evolutionary predictions are complicated by ecological feedbacks like density dependence, while ecological predictions can be complicated by evolutionary change. A widely used approach in micro-evolution, quantitative genetics,…

种群与进化 · 定量生物学 2015-09-07 Tim Coulson , Floriane Plard , Susanne Schindler , Arpat Ozgul , Jean-Michel Gaillard

We present a systematic review of some basic results on the derivation of classical epidemiological models from simple agent-based dynamics. The evolution of large populations is coupled with the dynamics of the contact distribution,…

种群与进化 · 定量生物学 2024-10-14 Mattia Zanella

We develop a continuous mathematical model of population dynamics that describes the sequential emergence of new genotypes under limited resources. The framework models genotype density as a nonlinear flow in mutation space, combining…

种群与进化 · 定量生物学 2025-12-10 Alexander Bratus , Tatiana Yakushkina , Vladimir Posvyanski

Inferring the driving equations of a dynamical system from population or time-course data is important in several scientific fields such as biochemistry, epidemiology, financial mathematics and many others. Despite the existence of…

机器学习 · 计算机科学 2020-12-10 Anastasios Tsourtis , Yannis Pantazis , Ioannis Tsamardinos

We propose a kinetic model to describe the dynamical evolution of wealth and knowledge in national and global markets, starting from a microscopic description of individual interactions. The model is built upon interaction rules that…

物理与社会 · 物理学 2026-02-24 Marzia Bisi , Martina Conte , Maria Groppi

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

偏微分方程分析 · 数学 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

种群与进化 · 定量生物学 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

Mathematical models of biological populations commonly use discrete structure classes to capture trait variation among individuals (e.g. age, size, phenotype, intracellular state). Upscaling these discrete models into continuum descriptions…

种群与进化 · 定量生物学 2026-03-18 Eleonora Agostinelli , Keith L. Chambers , Helen M. Byrne , Mohit P. Dalwadi

The aim of this paper is to study the derivation of appropriate meso- and macroscopic models for interactions as appearing in social processes. There are two main characteristics the models take into account, namely a network structure of…

偏微分方程分析 · 数学 2020-06-30 Martin Burger

In this paper we study a novel Fokker-Planck-type model that is designed to mimic manufacturing processes through the dynamics characterizing a large set of agents. In particular, we describe a many-agent system interacting with a target…

适应与自组织系统 · 物理学 2022-12-08 Ferdinando Auricchio , Giuseppe Toscani , Mattia Zanella
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