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County-level estimates of opioid use disorder (OUD) are essential for understanding the influence of local economic and social conditions. They provide policymakers with the granular information needed to identify, target, and implement…

Opioid overdose is a growing public health crisis in the United States. This crisis, recognized as "opioid epidemic," has widespread societal consequences including the degradation of health, and the increase in crime rates and family…

机器学习 · 计算机科学 2020-06-01 Ali Mert Ertugrul , Yu-Ru Lin , Tugba Taskaya-Temizel

The Mapper algorithm, a technique within topological data analysis (TDA), constructs a simplified graphical representation of high-dimensional data to uncover its underlying shape and structural patterns. The algorithm has attracted…

We apply topological data analysis, specifically the Mapper algorithm, to the U.S. COVID-19 data. The resulting Mapper graphs provide visualizations of the pandemic that are more complete than those supplied by other, more standard methods.…

种群与进化 · 定量生物学 2021-09-15 Yiran Chen , Ismar Volic

We describe two recently proposed machine learning approaches for discovering emerging trends in fatal accidental drug overdoses. The Gaussian Process Subset Scan enables early detection of emerging patterns in spatio-temporal data,…

计算机与社会 · 计算机科学 2017-10-09 Daniel B. Neill , William Herlands

Drug overdose mortality in the United States exhibits strong geographic heterogeneity and complex temporal evolution, yet most spatiotemporal studies focus on trends and risks without explicitly characterizing the underlying dynamical…

应用统计 · 统计学 2026-04-02 Dhrubajyoti Ghosh

Topological Data Analysis is a relatively new field of study that uses topological invariants to study the shape of data. We analyze a dataset provided by the Centers for Disease Control and Prevention (CDC) using persistent homology and…

代数拓扑 · 数学 2025-10-20 Megan Fairchild , Matthew Lemoine

Background: Opioid misuse is a major public health issue in the United States and in particular Ohio. However, the burden of the epidemic is challenging to quantify as public health surveillance measures capture different aspects of the…

应用统计 · 统计学 2018-06-15 Staci Hepler , Erin McKnight , Andrea Bonny , David Kline

Opioid overdose rates have increased in the United States over the past decade and reflect a major public health crisis. Modeling and prediction of drug and opioid hotspots, where a high percentage of events fall in a small percentage of…

机器学习 · 统计学 2023-02-14 Xueying Liu , Jeremy Carter , Brad Ray , George Mohler

The United States has an opioid epidemic, and Pennsylvania's Allegheny County is among the worst. This motivates a deeper exploration of what characterizes the epidemic, such as what are risk factors for people who ultimately overdose and…

应用统计 · 统计学 2018-04-25 Theresa Gebert , Shuli Jiang , Jiaxian Sheng

We explore the evolution of daily returns of four major US stock market indices during the technology crash of 2000, and the financial crisis of 2007-2009. Our methodology is based on topological data analysis (TDA). We use persistence…

数理金融 · 定量金融 2017-11-22 Marian Gidea , Yuri Katz

Opioid misuse is a national epidemic and a significant drug related threat to the United States. While the scale of the problem is undeniable, estimates of the local prevalence of opioid misuse are lacking, despite their importance to…

统计方法学 · 统计学 2023-05-12 Staci A. Hepler , David Kline , Andrea Bonny , Erin McKnight , Lance A. Waller

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

物理与社会 · 物理学 2024-03-14 Joyce Luo , Bartolomeo Stellato

Topological Data Analysis (TDA) is a novel statistical technique, particularly powerful for the analysis of large and high dimensional data sets. Much of TDA is based on the tool of persistent homology, represented visually via persistence…

应用统计 · 统计学 2017-11-07 Sarit Agami , Robert J. Adler

Spatial networks are ubiquitous in social, geographical, physical, and biological applications. To understand the large-scale structure of networks, it is important to develop methods that allow one to directly probe the effects of space on…

社会与信息网络 · 计算机科学 2020-09-23 Michelle Feng , Mason A. Porter

Topological Data Analysis (TDA) is a rigorous framework that borrows techniques from geometric and algebraic topology, category theory, and combinatorics in order to study the "shape" of such complex high-dimensional data. Research in this…

代数拓扑 · 数学 2022-04-15 R. W. R. Darling , John A. Emanuello , Emilie Purvine , Ahmad Ridley

Topological Data Analysis (TDA) is a recent approach to analyze data sets from the perspective of their topological structure. Its use for time series data has been limited to the field of financial time series primarily and as a method for…

机器学习 · 计算机科学 2019-06-18 Rodrigo Rivera-Castro , Polina Pilyugina , Alexander Pletnev , Ivan Maksimov , Wanyi Wyz , Evgeny Burnaev

We present a nation-wide network analysis of non-fatal opioid-involved overdose journeys in the United States. Leveraging a unique proprietary dataset of Emergency Medical Services incidents, we construct a journey-to-overdose geospatial…

社会与信息网络 · 计算机科学 2024-08-06 Lucas H. McCabe , Naoki Masuda , Shannon Casillas , Nathan Danneman , Alen Alic , Royal Law

The availability of geocoded health data and the inherent temporal structure of communicable diseases have led to an increased interest in statistical models and software for spatio-temporal data with epidemic features. The open source R…

统计计算 · 统计学 2017-05-12 Sebastian Meyer , Leonhard Held , Michael Höhle

Understanding the spread of any disease is a highly complex and interdisciplinary exercise as biological, social, geographic, economic, and medical factors may shape the way a disease moves through a population and options for its eventual…

种群与进化 · 定量生物学 2016-12-14 Aristides Moustakas
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