相关论文: ODE and PDE models for COVID-19, with reinfection …
This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…
In this research, we have derived a mathematical model for within human dynamics of COVID-19 infection using delay differential equations. The new model considers a 'latent period' and 'the time for immune response' as delay parameters,…
A coronavirus disease 2019 (COVID-19) model with quarantine and standard incidence rate is first developed, then a novel analysis approach for finding the ultimate lower bound of COVID-19 infectious individuals is proposed, which means that…
The outbreak of COVID-19, beginning in 2019 and continuing through the time of writing, has led to renewed interest in the mathematical modeling of infectious disease. Recent works have focused on partial differential equation (PDE) models,…
Genetic variations in the COVID-19 virus are one of the main causes of the COVID-19 pandemic outbreak in 2020 and 2021. In this article, we aim to introduce a new type of model, a system coupled with ordinary differential equations (ODEs),…
In [Ecological Complexity 44 (2020) Art. 100885, DOI: 10.1016/j.ecocom.2020.100885] a continuous-time compartmental mathematical model for the spread of the Coronavirus disease 2019 (COVID-19) is presented with Portugal as case study, from…
The outbreak of COVID-19 in 2020 has led to a surge in interest in the mathematical modeling of infectious diseases. Such models are usually defined as compartmental models, in which the population under study is divided into compartments…
This paper addresses the derivation of generic and tractable sufficient conditions ensuring the stability of a coupled system composed of a reaction-diffusion partial differential equation (PDE) and a finite-dimensional linear time…
Considering the propagation characteristics of COVID-19 in different regions, the dynamics analysis and numerical demonstration of long-term and short-term models of COVID-19 are carried out, respectively. The long-term model is devoted to…
This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…
We study the global stability issue of the reaction-convection-diffusion cholera epidemic PDE model and show that the basic reproduction number serves as a threshold parameter that predicts whether cholera will persist or become globally…
Raw data on the cumulative number of deaths at a country level generally indicate a spatially variable distribution of the incidence of COVID-19 disease. An important issue is to determine whether this spatial pattern is a consequence of…
In this study, we develop and analyze a nested multi-scale model for COVID -19 disease that integrates within-host scale and between-host scale sub-models. First, the well-posedness of the multi-scale model is discussed, followed by the…
The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…
Recent evidences show that individuals who recovered from COVID-19 can be reinfected. However, this phenomenon has rarely been studied using mathematical models. In this paper, we propose a SEIRE epidemic model to describe the spread of the…
The aim of this paper is to study the dynamics of a reaction--diffusion SIS (susceptible-infectious-susceptible) epidemic model with a nonlinear incidence rate describing the transmission of a communicable disease between individuals. We…
In this paper, we investigate a novel 3-compartment model of HIV infection of CD4$^+$ T-cells with a mass action term by including two versions: one baseline ODE model and one delay-differential equation (DDE) model with a constant discrete…
One clear aspect of behaviour in the COVID-19 pandemic has been people's focus on, and response to, reported or observed infection numbers in their community. We describe a simple model of infectious disease spread in a pandemic situation…
We propose a new model that describes the dynamics of epidemic spreading on connected graphs. Our model consists in a PDE-ODE system where at each vertex of the graph we have a standard SIR model and connexions between vertices are given by…
The COVID-19 epidemic has been spreading around the world for nearly three years, and asymptomatic infections have exacerbated the spread of the epidemic. To evaluate the role of asymptomatic infections in the spread of the epidemic, we…