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We introduce new classes of hydrodynamic theories inspired by the recently discovered fracton phases of quantum matter. Fracton phases are characterized by elementary excitations (fractons) with restricted mobility. The hydrodynamic…

强关联电子 · 物理学 2020-07-29 Andrey Gromov , Andrew Lucas , Rahul M. Nandkishore

We investigate the mechanics of an active droplet endowed with internal nematic order and surrounded by an isotropic Newtonian fluid. Using numerical simulations we demonstrate that, due to the interplay between the active stresses and the…

软凝聚态物质 · 物理学 2014-04-23 L. Giomi , A. DeSimone

Nucleosomes are the fundamental building blocks of chromatin that not only help in the folding of chromatin but also in carrying epigenetic information. It is known that nucleosome sliding is responsible for dynamically organizing chromatin…

生物物理 · 物理学 2022-08-31 Shantanu Kadam , Tripti Bameta , Ranjith Padinhateeri

Chromatin is a complex of DNA and specific proteins forming an intermediary level of organization of eukaryotic genomes, between double-stranded DNA and chromosome. Within a generic modeling of the chromatin assembly, we investigate the…

统计力学 · 物理学 2016-08-16 Eli Ben-Haïm , Annick Lesne , Jean-Marc Victor

Active networks made of biopolymers and motor proteins are valuable bioinspired systems that have been used in the last decades to study the cytoskeleton and its self-organization under mechanical stimulation. Different techniques are…

软凝聚态物质 · 物理学 2023-05-15 Vahid Nasirimarekani , Olinka Ramìrez-Soto , Stefan Karpitschka , Isabella Guido

Droplet formation has emerged as an essential concept for the spatiotemporal organisation of biomolecules in cells. However, classical descriptions of droplet dynamics based on passive liquid-liquid phase separation cannot capture the…

生物物理 · 物理学 2025-11-14 David Zwicker , Oliver W. Paulin , Cathelijne ter Burg

There is a long-standing question about the molecular configuration of interfacial water molecules in the proximity of solid surfaces, particularly carbon atoms which play a crucial role in electrochemistry and biology. In this study, the…

统计力学 · 物理学 2021-03-03 Iman Ahmadabadi , Ali Esfandiar , Ali Hassanali , Mohammad Reza Ejtehadi

Hydrodynamics provides a successful framework to effectively describe the dynamics of complex many-body systems ranging from subnuclear to cosmological scales by introducing macroscopic quantities such as particle densities and fluid…

Nucleosomes form the basic unit of compaction within eukaryotic genomes and their locations represent an important, yet poorly understood, mechanism of genetic regulation. Quantifying the strength of interactions within the nucleosome is a…

生物物理 · 物理学 2016-08-25 Joshua Lequieu , Andres Cordoba , David C. Schwartz , Juan J. de Pablo

Motivated by the unique physical properties of {\em biological active matter}, e.g., cytoskeletal dynamics in eukaryotic cells, we set up {\em effective} two-dimensional (2d) coarse-grained hydrodynamic equations for the dynamics of thin…

统计力学 · 物理学 2011-06-08 Niladri Sarkar , Abhik Basu

Cells are fundamental building blocks of living organisms displaying an array of shapes, morphologies, and textures that encode specific functions and physical behaviors. Elucidating the rules of this code remains a challenge. In this work,…

The nucleus of the eukaryotic cell functions amidst active cytoskeletal filaments, but its response to the stresses carried by these filaments is largely unexplored. We report here the results of studies of the translational and rotational…

生物物理 · 物理学 2017-08-23 Abhishek Kumar , Ananyo Maitra , Madhuresh Sumit , Sriram Ramaswamy , G. V. Shivashankar

Biological membranes are self-assembled complex fluid interfaces that host proteins, molecular motors and other macromolecules essential for cellular function. These membranes have a distinct in-plane fluid response with a surface viscosity…

流体动力学 · 物理学 2023-06-21 Vishnu Vig , Harishankar Manikantan

Dynamic structuring of water is a key player in a large class of processes underlying biochemical and technological developments today, the latter often involving electric fields. However, the anisotropic coupling between the water…

软凝聚态物质 · 物理学 2019-05-29 Andreas Baer , Zoran Miličević , David M. Smith , Ana-Sunčana Smith

Hydrodynamics is known to have strong effects on the kinetics of phase separation. There exist open questions on how such effects manifest in systems under confinement. Here, we have undertaken extensive studies of the kinetics of phase…

软凝聚态物质 · 物理学 2025-11-03 Saikat Basu , Suman Majumder , Raja Paul , Subir K. Das

Substrate-based cell motility is essential for fundamental biological processes, such as tissue growth, wound healing and immune response. Even if a comprehensive understanding of this motility mode remains elusive, progress has been…

细胞行为 · 定量生物学 2016-05-23 Wieland Marth , Axel Voigt

Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues.…

生物物理 · 物理学 2024-04-02 Jiayi Liu , Javier Boix-Campos , Jonathan E. Ron , Johan M. Kux , Nir S. Gov , Pablo J. Sáez

Proteases regulate various aspects of the life cycle in all organisms by cleaving specific peptide bonds. Their action is so central for biochemical processes that at least 2% of any known genome encodes for proteolytic enzymes. Here we…

生物大分子 · 定量生物学 2013-06-07 Vincenzo Carnevale , Simone Raugei , Cristian Micheletti , Paolo Carloni

In these Lecture Notes we aim at clarifying how soft matter physics, and herein notably statistical mechanics and fluid mechanics, can be engaged to understand and manipulate non-equilibrium systems consisting of numerous (microscopic)…

软凝聚态物质 · 物理学 2025-05-27 Jean-François Joanny , Joseph O. Indekeu

By generalizing a class of models recently introduced to account for protracted transients in biological systems, we identify a novel mechanism for hyperuniformity. In this model, competition of particles over a shared resource guides the…

统计力学 · 物理学 2025-12-11 Tal Agranov , Natan Wiegenfeld , Omer Karin , Benjamin D. Simons