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Face masks have been widely used as a protective measure against COVID-19. However, pre-pandemic empirical studies have produced mixed statistical results on the effectiveness of masks against respiratory viruses. The implications of the…

定量方法 · 定量生物学 2022-11-24 Pratyush K. Kollepara , Alexander F. Siegenfeld , Nassim Nicholas Taleb , Yaneer Bar-Yam

Incorporating vaccination into mathematical models appears deceptively simple: models integrate vaccine-derived protections, such as reduced susceptibility to infection, using parameters informed by empirical estimates of vaccine efficacy…

种群与进化 · 定量生物学 2026-05-19 Casey E. Middleton , Oliver Eales , James M. McCaw , Freya M. Shearer

The COVID-19 pandemic has heightened the urgency to understand and prevent pathogen transmission, specifically regarding infectious airborne particles. Extensive studies validate the understanding of larger (droplets) and smaller (aerosols)…

物理与社会 · 物理学 2023-10-25 Yaneer Bar-Yam , Jonathan M. Samet , Alexander F. Siegenfeld , Nassim N. Taleb

During the COVID-19 pandemic, estimating the total deaths averted by vaccination has been of great public health interest. Instead of estimating total deaths averted by vaccination among both vaccinated and unvaccinated individuals, some…

种群与进化 · 定量生物学 2025-10-09 Katherine M. Jia , Christopher B. Boyer , Alyssa Bilinski , Marc Lipsitch

Knowing the true effect size of clinical interventions in randomised clinical trials is key to informing the public health policies. Vaccine efficacy is defined in terms of the relative risk or the ratio of two disease risks. However, only…

统计方法学 · 统计学 2021-02-03 Yasin Memari

COVID-19 pandemic is one of the major disasters that humanity has ever faced. In this paper, we try to model the effect of vaccination in controlling the pandemic, particularly in context to the third wave which is predicted to hit…

种群与进化 · 定量生物学 2022-07-27 Sourav Chowdhury , Suparna Roychowdhury , Indranath Chaudhuri

By the end of 2020, a year since the first cases of infection by the Covid-19 virus have been reported, there is a light at the end of the tunnel. Several pharmaceutical companies made significant progress in developing effective vaccines…

种群与进化 · 定量生物学 2021-08-04 Hilla De-Leon , Francesco Pederiva

Recently, attention was drawn to the failure of two very large internet-based probability surveys to correctly estimate COVID-19 vaccine uptake in the United States in early 2021. Both the Delphi-Facebook CTIS and Census Household Pulse…

应用统计 · 统计学 2024-09-27 Rebecca R Andridge

We analyze the susceptible-infected-susceptible model for epidemic spreading in which a fraction of the individuals become immune by vaccination. This process is understood as a dilution by vaccination, which decreases the fraction of the…

种群与进化 · 定量生物学 2021-11-10 Tânia Tomé , Mário J. de Oliveira

Optimization of vaccine allocations among different segments of a heterogeneous population is important for enhancing the effectiveness of vaccination campaigns in reducing the burden of epidemics. Intuitively, it would seem that…

定量方法 · 定量生物学 2022-12-01 Nir Gavish , Guy Katriel

Vaccines are the most powerful pharmaceutical tool to combat the COVID-19 pandemic. While the majority (about 65%) of the German population were fully vaccinated, incidence started growing exponentially in October 2021 with about 41% of…

Miss-information is usually adjusted to fit distinct narratives and can propagate rapidly through communities of interest, which work as echo chambers, cause reinforcement and foster confirmation bias. False beliefs, once adopted, are…

物理与社会 · 物理学 2020-09-30 Rafael Prieto Curiel , Humberto González Ramírez

Polarization of opinions about vaccination can have a negative impact on pandemic control. In this work we quantify this negative impact for the transmission of COVID-19, using an agent based simulation in an heterogeneous population with…

物理与社会 · 物理学 2022-06-02 Ixandra Achitouv

With significant population fractions in many societies who refuse vaccines, it is important to reconsider how vaccination is incorporated into compartmental epidemiology models. It is still most common to apply the vaccination rate to the…

种群与进化 · 定量生物学 2026-03-09 Glenn Ledder

The Covid-19 pandemic revealed the difficulties of vaccinating a population under the circumstances marked by urgency and limited availability of doses while balancing benefits associated with distinct guidelines satisfying specific ethical…

定量方法 · 定量生物学 2023-06-08 Pedro Ribeiro de Almeida , Vitor Hirata Sanches , Carla Goldman

Given limited supply of approved vaccines and constrained medical resources, design of a vaccination strategy to control a pandemic is an economic problem. We use time-series and panel methods with real-world country-level data to estimate…

综合经济学 · 经济学 2022-01-19 Dongwoo Kim , Young Jun Lee

Vaccine randomized trials are typically designed to be blinded, ensuring that the estimated vaccine efficacy (VE) reflects the immunological effect of the vaccine. When blinding is broken, however, the estimated VE reflects not only the…

统计方法学 · 统计学 2026-03-12 Rachel Axelrod , Uri Obolski , Daniel Nevo

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

统计方法学 · 统计学 2023-06-26 Chih-Li Sung , Ying Hung

This study assesses the impact of COVID-19 vaccines through an epidemiological model that quantifies their role in pandemic control. We analyze an SIR-based model incorporating vaccination effects and calculate the basic reproduction…

动力系统 · 数学 2025-07-29 Tesfalem Abate Tegegn , Yibeltal Adane Terefe

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

种群与进化 · 定量生物学 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin
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