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We develop a Gaussian-process mixture model for heterogeneous treatment effect estimation that leverages the use of transformed outcomes. The approach we will present attempts to improve point estimation and uncertainty quantification…

统计方法学 · 统计学 2018-12-19 Abbas Zaidi , Sayan Mukherjee

Bivariate count data arise in several different disciplines (epidemiology, marketing, sports statistics, etc., to name but a few) and the bivariate Poisson distribution which is a generalization of the Poisson distribution plays an…

统计方法学 · 统计学 2023-01-12 Barry C. Arnold , Indranil Ghosh

There has been definite progress recently in proving the variational single-letter formula given by the heuristic replica method for various estimation problems. In particular, the replica formula for the mutual information in the case of…

信息论 · 计算机科学 2018-11-16 Jean Barbier , Nicolas Macris , Antoine Maillard , Florent Krzakala

Population adjustment methods such as matching-adjusted indirect comparison (MAIC) are increasingly used to compare marginal treatment effects when there are cross-trial differences in effect modifiers and limited patient-level data. MAIC…

统计方法学 · 统计学 2022-05-12 Antonio Remiro-Azócar , Anna Heath , Gianluca Baio

This paper describes a Bayesian method for learning causal networks using samples that were selected in a non-random manner from a population of interest. Examples of data obtained by non-random sampling include convenience samples and…

人工智能 · 计算机科学 2013-01-18 Gregory F. Cooper

In cluster randomized trials, the average treatment effect among individuals (i-ATE) can be different from the cluster average treatment effect (c-ATE) when informative cluster size is present, i.e., when treatment effects or participant…

统计方法学 · 统计学 2025-10-02 Bryan S. Blette , Zhe Chen , Brennan C. Kahan , Andrew Forbes , Michael O. Harhay , Fan Li

Linear mixed effects models are widely used in statistical modelling. We consider a mixed effects model with Bayesian variable selection in the random effects using spike-and-slab priors and developed a variational Bayes inference scheme…

统计方法学 · 统计学 2024-08-15 M-Z. Spyropoulou , J. Hopker , J. E. Griffin

Compared to mean regression and quantile regression, the literature on modal regression is very sparse. A unifying framework for Bayesian modal regression is proposed, based on a family of unimodal distributions indexed by the mode, along…

统计方法学 · 统计学 2024-07-02 Qingyang Liu , Xianzheng Huang , Rai Bai

Many statistical models are given in the form of non-normalized densities with an intractable normalization constant. Since maximum likelihood estimation is computationally intensive for these models, several estimation methods have been…

统计理论 · 数学 2021-09-01 Takeru Matsuda , Masatoshi Uehara , Aapo Hyvarinen

Population-adjusted indirect comparisons estimate treatment effects when access to individual patient data is limited and there are cross-trial differences in effect modifiers. Popular methods include matching-adjusted indirect comparison…

应用统计 · 统计学 2021-11-05 Antonio Remiro-Azócar , Anna Heath , Gianluca Baio

In many scientific settings data can be naturally partitioned into variable groupings called views. Common examples include environmental (1st view) and genetic information (2nd view) in ecological applications, chemical (1st view) and…

应用统计 · 统计学 2009-06-08 Mark Culp , George Michailidis , Kjell Johnson

Nonlinear mixed effects models represent a powerful tool to simultaneously analyze data from several individuals. In this study a compartmental model of leucine kinetics is examined and extended with a stochastic differential equation to…

定量方法 · 定量生物学 2011-01-05 Martin Berglund , Mikael Sunnåker , Martin Adiels , Mats Jirstrand , Bernt Wennberg

When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated…

机器学习 · 计算机科学 2013-02-21 George H. John , Pat Langley

Forecasting techniques for assessing the power of future experiments to discriminate between theories or discover new laws of nature are of great interest in many areas of science. In this paper, we introduce a Bayesian forecasting method…

数据分析、统计与概率 · 物理学 2024-09-24 Mohammad Hossein Namjoo

For prediction models developed on clustered data that do not account for cluster heterogeneity in model parameterization, it is crucial to use cluster-based validation to assess model generalizability on unseen clusters. This paper…

统计方法学 · 统计学 2025-06-23 Jiaxing Qiu , Douglas E. Lake , Pavel Chernyavskiy , Teague R. Henry

Traditionally, spline or kernel approaches in combination with parametric estimation are used to infer the linear coefficient (fixed effects) in a partially linear mixed-effects model for repeated measurements. Using machine learning…

统计方法学 · 统计学 2023-04-03 Corinne Emmenegger , Peter Bühlmann

Conditional copulas are flexible statistical tools that couple joint conditional and marginal conditional distributions. In a linear regression setting with more than one covariate and two dependent outcomes, we propose the use of additive…

统计方法学 · 统计学 2014-07-31 Avideh Sabeti , Mian Wei , Radu V. Craiu

The most widely discussed methods for estimating the Average Causal Effect/Average Treatment Effect are those for intervention in discrete binary variables whose value represents intervention/non-intervention groups. On the other hand,…

机器学习 · 统计学 2022-03-21 Yoshiaki Kitazawa

The first investigation is made of designs for screening experiments where the response variable is approximated by a generalised linear model. A Bayesian information capacity criterion is defined for the selection of designs that are…

统计方法学 · 统计学 2016-10-27 David C. Woods , James M. McGree , Susan M. Lewis

A clustered adaptive intervention (cAI) is a pre-specified sequence of decision rules that guides practitioners on how best - and based on which measures - to tailor cluster-level intervention to improve outcomes at the level of individuals…

统计方法学 · 统计学 2025-05-05 Yao Song , Kelly Speth , Amy Kilbourne , Andrew Quanbeck , Daniel Almirall , Lu Wang