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Diabetes mellitus is a disease that affects to hundreds of millions of people worldwide. Maintaining a good control of the disease is critical to avoid severe long-term complications. In recent years, several artificial pancreas systems…

Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…

机器学习 · 计算机科学 2025-11-27 Mirko Paolo Barbato , Giorgia Rigamonti , Davide Marelli , Paolo Napoletano

Blood glucose (BG) management is crucial for type-1 diabetes patients resulting in the necessity of reliable artificial pancreas or insulin infusion systems. In recent years, deep learning techniques have been utilized for a more accurate…

机器学习 · 计算机科学 2021-01-19 Md Fazle Rabby , Yazhou Tu , Md Imran Hossen , Insup Le , Anthony S Maida , Xiali Hei

Recent advances in SSL enabled novel medical AI models, known as foundation models, offer great potential for better characterizing health from diverse biomedical data. CGM provides rich, temporal data on glycemic patterns, but its full…

We propose and create an incentive based recommendation algorithm aimed at improving the lifestyle of diabetic patients. This algorithm is integrated into a real world mobile application to provide personalized health recommendations.…

人机交互 · 计算机科学 2025-04-22 Wasim Abbas , Hafiz Syed Muhammad Bilal , Asim Abbas , Muhammad Afzal , Je-Hoon Lee

While the Artificial Pancreas is effective in regulating the blood glucose in the safe range of 70-180 mg/dl in type 1 diabetic patients, the high intra-patient variability, as well as exogenous meal disturbances, poses a serious challenge.…

系统与控制 · 电气工程与系统科学 2022-06-30 Bhabani Shankar Dey , Anirudh Nath , Abhilash Patel , Indra Narayan Kar

Diabetes is a civilization chronic disease characterized by a constant elevated concentration of glucose in the blood. Many processes are involved in the glucose regulation, and their interactions are very complex. To better understand…

细胞行为 · 定量生物学 2025-06-02 Kamila Barylska , Franck Delaplace , Anna Gogolińska , Ewa Pańkowska

Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…

机器学习 · 统计学 2025-09-18 Antonio Álvarez-López , Marcos Matabuena

The challenge of handling missing data is widespread in modern data analysis, particularly during the preprocessing phase and in various inferential modeling tasks. Although numerous algorithms exist for imputing missing data, the…

统计方法学 · 统计学 2024-03-28 Marcos Matabuena , Carla Díaz-Louzao , Rahul Ghosal , Francisco Gude

Calculating mealtime insulin doses poses a significant challenge for individuals with Type 1 Diabetes (T1D). Doses should perfectly compensate for expected post-meal glucose excursions, requiring a profound understanding of the individual's…

定量方法 · 定量生物学 2024-06-24 Anas El Fathi , Elliott Pryor , Marc D. Breton

Cold-chain storage limits access to insulin for hundreds of millions of people; a thermally protective patch polymer could help, but the design space is too large for exhaustive experiment. Starting from that problem, we narrow to an…

定量方法 · 定量生物学 2026-05-20 Martins Otun

Diabetes mellitus is a growing global health issue, with Type 1 Diabetes (T1D) requiring constant monitoring to avoid hypoglycemia. Although Continuous Glucose Monitors (CGMs) are effective, their cost and invasiveness limit access,…

人机交互 · 计算机科学 2025-09-23 Lawrence Obiuwevwi , Krzysztof J. Rechowicz , Vikas Ashok , Sampath Jayarathna

This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller, designed to operate as an artificial pancreas for Type 1 diabetes. The primary challenge in diabetes…

系统与控制 · 电气工程与系统科学 2025-03-11 Omar Mameche , Abdelhadi Abedou , Taqwa Mezaache , Mohamed Tadjine

The availability of continuous glucose monitors as over-the-counter commodities have created a unique opportunity to monitor a person's blood glucose levels, forecast blood glucose trajectories and provide automated interventions to prevent…

机器学习 · 计算机科学 2026-04-16 Ebrahim Farahmand , Shovito Barua Soumma , Nooshin Taheri Chatrudi , Hassan Ghasemzadeh

Clinical time-series forecasting is increasingly studied for decision support, yet standard aggregate metrics can obscure whether a model is actually useful for the task it is meant to serve. In safety-critical settings, low average error…

机器学习 · 计算机科学 2026-05-04 Alireza Namazi , Heman Shakeri

People with diabetes have to manage their blood glucose level to keep it within an appropriate range. Predicting whether future glucose values will be outside the healthy threshold is of vital importance in order to take corrective actions…

机器学习 · 计算机科学 2023-04-03 J. Alvarado , J. Manuel Velasco , F. Chávez , J. Ignacio Hidalgo , F. Fernández de Vega

We develop a new model of insulin-glucose dynamics for forecasting blood glucose in type 1 diabetics. We augment an existing biomedical model by introducing time-varying dynamics driven by a machine learning sequence model. Our model…

机器学习 · 统计学 2020-08-10 Andrew C. Miller , Nicholas J. Foti , Emily Fox

Introduction: To leverage functionality and clinical relevance into understanding systems biology, one needs to understand the pathway of the genetic effects on risk factors/disease through intermediate molecular levels, such as…

基因组学 · 定量生物学 2018-09-14 Azam Yazdani , Akram Yazdani , Philip L. Lorenzi , Ahmad Samiei

Oral Glucose Tolerance Test (OGTT) is one of many way to produce data in the study of the diabetes dynamic. In a recent paper [1.]:\textit{ Estimating insulin sensitivity and $ \beta $-cell function from the oral glucose tolerance test:…

概率论 · 数学 2024-12-17 Paul Bekima

With the growing prevalence of diabetes and the associated public health burden, it is crucial to identify modifiable factors that could improve patients' glycemic control. In this work, we seek to examine associations between medication…

应用统计 · 统计学 2025-12-22 Alexander Coulter , Rashmi N. Aurora , Naresh M. Punjabi , Irina Gaynanova