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In randomized experiments, interactions between units might generate a treatment diffusion process. This is common when the treatment of interest is an actual object or product that can be shared among peers (e.g., flyers, booklets,…

统计方法学 · 统计学 2021-09-17 Costanza Tortú , Irene Crimaldi , Fabrizia Mealli , Laura Forastiere

While sample sizes in randomized clinical trials are large enough to estimate the average treatment effect well, they are often insufficient for estimation of treatment-covariate interactions critical to studying data-driven precision…

机器学习 · 统计学 2020-04-22 Steve Yadlowsky , Fabio Pellegrini , Federica Lionetto , Stefan Braune , Lu Tian

As an important problem in causal inference, we discuss the estimation of treatment effects (TEs). Representing the confounder as a latent variable, we propose Intact-VAE, a new variant of variational autoencoder (VAE), motivated by the…

机器学习 · 统计学 2022-04-22 Pengzhou Wu , Kenji Fukumizu

This paper combines causal mediation analysis with double machine learning to control for observed confounders in a data-driven way under a selection-on-observables assumption in a high-dimensional setting. We consider the average indirect…

计量经济学 · 经济学 2021-02-17 Helmut Farbmacher , Martin Huber , Lukáš Lafférs , Henrika Langen , Martin Spindler

An individual has been subjected to some exposure and has developed some outcome. Using data on similar individuals, we wish to evaluate, for this case, the probability that the outcome was in fact caused by the exposure. Even with the best…

统计理论 · 数学 2017-06-16 Rossella Murtas , Alexander Philip Dawid , Monica Musio

Death among subjects is common in observational studies evaluating the causal effects of interventions among geriatric or severely ill patients. High mortality rates complicate the comparison of the prevalence of adverse events (AEs)…

统计方法学 · 统计学 2024-10-08 Anthony Sisti , Andrew Zullo , Roee Gutman

Many areas of research are characterised by the deluge of large-scale highly-dimensional time-series data. However, using the data available for prediction and decision making is hampered by the current lag in our ability to uncover and…

人工智能 · 计算机科学 2020-11-24 Zina Ibrahim , Honghan Wu , Richard Dobson

Matching and weighting methods for observational studies involve the choice of an estimand, the causal effect with reference to a specific target population. Commonly used estimands include the average treatment effect in the treated (ATT),…

统计方法学 · 统计学 2023-07-12 Noah Greifer , Elizabeth A. Stuart

Mediation analysis is difficult when the number of potential mediators is larger than the sample size. In this paper we propose new inference procedures for the indirect effect in the presence of high-dimensional mediators for linear…

统计方法学 · 统计学 2019-10-29 Ruixuan Rachel Zhou , Liewei Wang , Sihai Dave Zhao

Micro-randomized trials (MRTs) play a crucial role in optimizing digital interventions. In an MRT, each participant is sequentially randomized among treatment options hundreds of times. While the interventions tested in MRTs target…

统计方法学 · 统计学 2025-09-04 Tianchen Qian

Bipartite experiments are a recent object of study in causal inference, whereby treatment is applied to one set of units and outcomes of interest are measured on a different set of units. These experiments are particularly useful in…

Path-specific effects are a broad class of mediated effects from an exposure to an outcome via one or more causal pathways with respect to some subset of intermediate variables. The majority of the literature concerning estimation of…

统计方法学 · 统计学 2017-10-06 Caleb H. Miles , Ilya Shpitser , Phyllis Kanki , Seema Meloni , Eric J. Tchetgen Tchetgen

We study the problem of efficiently estimating the effect of an intervention on a single variable (atomic interventions) using observational samples in a causal Bayesian network. Our goal is to give algorithms that are efficient in both…

机器学习 · 计算机科学 2020-08-07 Arnab Bhattacharyya , Sutanu Gayen , Saravanan Kandasamy , Ashwin Maran , N. V. Vinodchandran

The Average Treatment Effect (ATE) is a foundational metric in causal inference, widely used to assess intervention efficacy in randomized controlled trials (RCTs). However, in many applications -- particularly in healthcare -- this static…

机器学习 · 计算机科学 2025-07-23 Julianna Piskorz , Krzysztof Kacprzyk , Harry Amad , Mihaela van der Schaar

Media is evolving from traditional linear narratives to personalised experiences, where control over information (or how it is presented) is given to individual audience members. Measuring and understanding audience engagement with this…

人机交互 · 计算机科学 2021-08-05 Jonathan Carlton , Andy Brown , Caroline Jay , John Keane

In the field of disparities research, there has been growing interest in developing a counterfactual-based decomposition analysis to identify underlying mediating mechanisms that help reduce disparities in populations. Despite rapid…

统计方法学 · 统计学 2022-05-27 Soojin Park , Chioun Lee , Xu Qin

Causal inference studies whether the presence of a variable influences an observed outcome. As measured by quantities such as the "average treatment effect," this paradigm is employed across numerous biological fields, from vaccine and drug…

In cluster-randomized trials (CRTs), there is emerging interest in exploring the causal mechanism in which a cluster-level treatment affects the outcome through an intermediate outcome. The majority of existing causal mediation methods are…

统计方法学 · 统计学 2026-01-12 Chao Cheng , Fan Li

In many observational studies in social science and medicine, subjects or units are connected, and one unit's treatment and attributes may affect another's treatment and outcome, violating the stable unit treatment value assumption (SUTVA)…

统计方法学 · 统计学 2024-06-25 Zhaonan Qu , Ruoxuan Xiong , Jizhou Liu , Guido Imbens

Competing risk is a common phenomenon when dealing with time-to-event outcomes in biostatistical applications. An attractive estimand in this setting is the "number of life-years lost due to a specific cause of death", Andersen et al.…

统计方法学 · 统计学 2025-02-04 Simon Christoffer Ziersen , Torben Martinussen