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When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again.…

种群与进化 · 定量生物学 2015-01-15 Maria Vittoria Barbarossa , Gergely Röst

Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity. In some disease systems, the process of waning immunity can be…

种群与进化 · 定量生物学 2017-08-10 Tiffany Leung , Barry D Hughes , Federico Frascoli , Patricia T Campbell , James M McCaw

The outbreak of mutant strains and vaccination behaviors have been the focus of recent epidemiological research, but most existing epidemic models failed to simultaneously capture viral mutation and consider the complexity and behavioral…

种群与进化 · 定量生物学 2026-01-16 Wenjie Zhang , Yusheng Li , Qin Li , Guojun Huang , Minyu Feng

This is an epidemiological SIRV model based study that is designed to analyze the impact of vaccination in containing infection spread, in a 4-tiered population compartment comprised of susceptible, infected, recovered and vaccinated…

种群与进化 · 定量生物学 2018-11-14 Ewa Grela , Michael Stich , Amit K Chattopadhyay

The Markovian approach, which assumes exponentially distributed interinfection times, is dominant in epidemic modeling. However, this assumption is unrealistic as an individual's infectiousness depends on its viral load and varies over…

种群与进化 · 定量生物学 2023-08-02 Qihui Yang , Joan Saldaña , Caterina Scoglio

The dynamics of strongly immunizing childhood infections is still not well understood. Although reports of successful modeling of several incidence data records can be found in the literature, the key determinants of the observed temporal…

种群与进化 · 定量生物学 2012-10-09 Ganna Rozhnova , Ana Nunes

Immune events such as infection, vaccination, and a combination of the two result in distinct time-dependent antibody responses in affected individuals. These responses and event prevalences combine non-trivially to govern antibody levels…

种群与进化 · 定量生物学 2024-04-16 Prajakta Bedekar , Rayanne A. Luke , Anthony J. Kearsley

This study presents a family of stochastic models for the dynamics of influenza in a closed human population. We consider treatment for the disease in the form of vaccination, and incorporate the periods of effectiveness of the vaccine and…

种群与进化 · 定量生物学 2020-05-05 Divine Wanduku

We study the spread of an SIRS-type epidemic with vaccination on network. Starting from an exact Markov description of the model, we investigate the mean epidemic lifetime by providing a sufficient condition for fast extinction that depends…

动力系统 · 数学 2020-11-23 Stefania Ottaviano , Stefano Bonaccorsi

We study the SIRS (Susceptible-Infected-Recovered-Susceptible) spreading processes over complex networks, by considering its exact $3^n$-state Markov chain model. The Markov chain model exhibits an interesting connection with its $2n$-state…

社会与信息网络 · 计算机科学 2016-03-17 Navid Azizan Ruhi , Babak Hassibi

A stochastic epidemic model accounting for the effect of contact-tracing on the spread of an infectious disease is studied. Precisely, individuals identified as infected may contribute to detecting other infectious individuals by providing…

概率论 · 数学 2009-03-28 Stéphan Clémençon , Viet Chi Tran , Hector De Arazoza

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

应用统计 · 统计学 2018-01-30 Tom Britton

We study a susceptible-vaccinated--infected--recovered (SVIR) epidemic-spreading model with diversity of infection rate of the individuals. By means of analytical arguments as well as extensive computer simulations, we demonstrate that the…

物理与社会 · 物理学 2013-12-05 Chao-Ran Cai , Zhi-Xi wu , Jian-Yue Guan

Mathematical models represent one of the fundamental ways of studying nature. In special, epidemic models have shown to be particularly useful in the understanding of the course of diseases and in the planning effective control policies. A…

物理与社会 · 物理学 2022-10-19 Paulo C. Ventura , Eric K. Tokuda , Luciano da F. Costa , Francisco A. Rodrigues

In this paper, we extend the classical SIRS (Susceptible-Infectious-Recovered-Susceptible) model from mathematical epidemiology by incorporating a vaccinated compartment, V, accounting for an imperfect vaccine with waning efficacy over…

种群与进化 · 定量生物学 2025-01-30 Joseph Páez Chávez , Aytül Gökçe , Thomas Götz , Burcu Gürbüz

Understanding the dynamics of antibody levels is crucial for characterizing the time-dependent response to immune events: either infections or vaccinations. The sequence and timing of these events significantly influence antibody level…

This paper focuses on and analyzes realistic SIR models that take stochasticity into account. The proposed systems are applicable to most incidence rates that are used in the literature including the bilinear incidence rate, the…

概率论 · 数学 2024-07-10 Nguyen Du , Alexandru Hening , Nhu Nguyen , George Yin

We adapt the article of Forien, Pang, Pardoux and Zotsa: Arxiv preprint Arxiv2210.04667(2022), on epidemic models with varying infectivity and waning immunity, to incorporate the memory of the last infection. To this end, we introduce a…

概率论 · 数学 2025-05-02 Hélène Guérin , Arsene Brice Zotsa-Ngoufack

We consider the spread of a supercritical stochastic SIR (Susceptible, Infectious, Recovered) epidemic on a configuration model random graph. We mainly focus on the final stages of a large outbreak and provide limit results for the duration…

概率论 · 数学 2020-02-26 Abid Ali Lashari , Ana Serafimović , Pieter Trapman

We study the spread of discrete-time epidemics over arbitrary networks for well-known propagation models, namely SIS (susceptible-infected-susceptible), SIR (susceptible-infected-recovered), SIRS (susceptible-infected-recovered-susceptible)…

社会与信息网络 · 计算机科学 2016-10-03 Navid Azizan Ruhi , Hyoung Jun Ahn , Babak Hassibi
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