相关论文: Individual-level models of disease transmission in…
Here, we introduce a novel framework for modelling the spatiotemporal dynamics of disease spread known as conditional logistic individual-level models (CL-ILM's). This framework alleviates much of the computational burden associated with…
Spatial individual-level models (ILMs) provide a flexible framework for modelling infectious disease transmission across populations with known locations. Bayesian inference for these models relies on Markov chain Monte Carlo (MCMC), which…
Infectious disease models can be of great use for understanding the underlying mechanisms that influence the spread of diseases and predicting future disease progression. Modeling has been increasingly used to evaluate the potential impact…
During epidemics, people will often modify their behaviour patterns over time in response to changes in their perceived risk of spreading or contracting the disease. This can substantially impact the trajectory of the epidemic. However,…
Infectious diseases have severe health and economic consequences for society. It is important in controlling the spread of an emerging infectious disease to be able to both estimate the parameters of the underlying model and identify those…
In this article, we introduce the R package EpiILM, which provides tools for simulation from, and inference for, discrete-time individual-level models of infectious disease transmission proposed by Deardon et al. (2010). The inference is…
One of the most important issues in the critical assessment of spatio-temporal stochastic models for epidemics is the selection of the transmission kernel used to represent the relationship between infectious challenge and spatial…
The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…
The primary tool for predicting infectious disease spread and intervention effectiveness is the mass action Susceptible-Infected-Recovered model of Kermack and McKendrick. Its usefulness derives largely from its conceptual and mathematical…
Statistical models used to estimate the spatio-temporal pattern in disease risk from areal unit data represent the risk surface for each time period with known covariates and a set of spatially smooth random effects. The latter act as a…
Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…
This paper describes the R package EpiILMCT, which allows users to study the spread of infectious disease using continuous time individual level models (ILMs). The package provides tools for simulation from continuous time ILMs that are…
Increasing rates of global trade and travel, as well as changing climatic patterns, have led to more frequent outbreaks of plant disease epidemics worldwide. Mathematical modelling is a key tool in predicting where and how these new threats…
Individual-level epidemic models are increasingly being used to help understand the transmission dynamics of various infectious diseases. However, fitting such models to individual-level epidemic data is challenging, as we often only know…
The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…
Besides mimicking bio-chemical and multi-scale communication mechanisms, molecular communication forms a theoretical framework for virus infection processes. Towards this goal, aerosol and droplet transmission has recently been modeled as a…
We propose a framework for Bayesian non-parametric estimation of the rate at which new infections occur assuming that the epidemic is partially observed. The developed methodology relies on modelling the rate at which new infections occur…
We introduce Pathogen.jl for simulation and inference of transmission network individual level models (TN-ILMs) of infectious disease spread in continuous time. TN-ILMs can be used to jointly infer transmission networks, event times, and…
Motivated by foot-and-mouth disease (FMD) outbreak data from Turkey, we develop a model to estimate disease risk based on a space-time record of outbreaks. The spread of infectious disease in geographical units depends on both transmission…
Emerging marine infectious diseases pose a substantial threat to marine ecosystems and the conservation of their biodiversity. Compartmental models of epidemic transmission in marine sessile organisms, available only recently, are based on…