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It is increasingly common to encounter prediction tasks in the biomedical sciences for which multiple datasets are available for model training. Common approaches such as pooling datasets and applying standard statistical learning methods…

机器学习 · 统计学 2021-10-05 Gabriel Loewinger , Rolando Acosta Nunez , Rahul Mazumder , Giovanni Parmigiani

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

种群与进化 · 定量生物学 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

We study the elective surgery planning problem in a hospital with operation rooms shared by elective and emergency patients. This problem can be split in two distinct phases. First, a subset of patients to be operated in the next planning…

最优化与控制 · 数学 2024-03-07 Mohammed Majthoub Almoghrabi , Guillaume Sagnol

This document analyzes the role of data-driven methodologies in Covid-19 pandemic. We provide a SWOT analysis and a roadmap that goes from the access to data sources to the final decision-making step. We aim to review the available…

种群与进化 · 定量生物学 2020-06-11 Teodoro Alamo , D. G. Reina , Pablo Millán

In modern distributed computing systems, unpredictable and unreliable infrastructures result in high variability of computing resources. Meanwhile, there is significantly increasing demand for timely and event-driven services with deadline…

分布式、并行与集群计算 · 计算机科学 2019-04-12 Chien-Sheng Yang , Ramtin Pedarsani , A. Salman Avestimehr

With the simultaneous rise of energy costs and demand for cloud computing, efficient control of data centers becomes crucial. In the data center control problem, one needs to plan at every time step how many servers to switch on or off in…

性能 · 计算机科学 2018-01-25 Paul Weng , Zeqi Qiu , John Costanzo , Xiaoqi Yin , Bruno Sinopoli

This study focuses on relay transport carriers (RTCs) that contract with hub providers to lease hub capacity and employ relay transportation via hubs. It enables long-haul freight shipments to be transported by multiple short-haul drivers…

最优化与控制 · 数学 2024-06-25 Xiaoyue Liu , Jingze Li , Mathieu Dahan , Benoit Montreuil

We study a resource allocation problem for containing an infectious disease in a metapopulation subject to resource uncertainty. We propose a two-stage model where the policy maker seeks to allocate resources in both stages where the second…

最优化与控制 · 数学 2020-06-03 Ceyda Yaba Best , Amin Khademi , Burak Eksioglu

Problem definition: Access to accurate predictions of patients' outcomes can enhance medical staff's decision-making, which ultimately benefits all stakeholders in the hospitals. A large hospital network in the US has been collaborating…

This paper proposes a fully distributed Demand-Side Management system for Smart Grid infrastructures, especially tailored to reduce the peak demand of residential users. In particular, we use a dynamic pricing strategy, where energy tariffs…

计算机科学与博弈论 · 计算机科学 2014-05-09 Antimo Barbato , Antonio Capone , Lin Chen , Fabio Martignon , Stefano Paris

Epidemics are a serious public health threat, and the resources for mitigating their effects are typically limited. Decision-makers face challenges in forecasting the supply and demand for these resources as prior information about the…

In this paper, we consider the expansion of power grids under emerging large loads from data centers and electrified manufacturing. We develop a multi-period grid capacity expansion model to determine optimal investment profiles for power…

系统与控制 · 电气工程与系统科学 2026-05-29 Jiyong Lee , Melody Agustin , Joanne Langsdorf , Erhan Kutanolgu , Michael Baldea , Ilias Mitrai

Sustainable energy systems require flexible elements to balance the variability of renewable energy sources. Demand response aims to adapt the demand to the variable generation, in particular by shifting the load in time. In this article,…

物理与社会 · 物理学 2022-07-04 Chengyuan Han , Dirk Witthaut , Leonardo Rydin Gorjão , Philipp C. Böttcher

After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for…

机器学习 · 计算机科学 2021-02-10 Chun-An Chou , Qingtao Cao , Shao-Jen Weng , Che-Hung Tsai

Background: Most acute stroke (AS) patients in the United States are initially evaluated at a primary stroke center (PSC) and a significant proportion requires transfer to a comprehensive stroke center (CSC) for advanced treatment. A CSC…

定量方法 · 定量生物学 2022-02-16 Hojun Choi , Ohad Perry , Jane Holl , Shyam Prabhakaran

Staff scheduling is a well-known problem in operations research and finds its application at hospitals, airports, supermarkets, and many others. Its goal is to assign shifts to staff members such that a certain objective function, e.g.…

离散数学 · 计算机科学 2026-04-28 Debsankha Manik , Rico Raber

Background: Emergency department (ED) overcrowding remains a major challenge, causing delays in care and increased operational strain. Hospital management often reacts to congestion after it occurs. Machine learning predictive modeling…

机器学习 · 计算机科学 2025-04-29 Orhun Vural , Bunyamin Ozaydin , Khalid Y. Aram , James Booth , Brittany F. Lindsey , Abdulaziz Ahmed

The recovery of the public transportation system is critical for both social re-engagement and economic rebooting after the shutdown during pandemic like COVID-19. In this study, we focus on the integrated optimization of service line…

综合经济学 · 经济学 2021-09-10 Yiduo Huang , Zuojun Max Shen

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

种群与进化 · 定量生物学 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

Line planning in public transport is the strategic problem of selecting lines and their operating frequencies. This problem is important as it defines the passenger service, based on available connections and expected travel times, and…