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Experimenters often collect baseline data to study heterogeneity. I propose the first valid confidence intervals for the VCATE, the treatment effect variance explained by observables. Conventional approaches yield incorrect coverage when…

计量经济学 · 经济学 2023-06-07 Alejandro Sanchez-Becerra

When studying treatment effects in multilevel studies, investigators commonly use (semi-)parametric estimators, which make strong parametric assumptions about the outcome, the treatment, and/or the correlation structure between study units…

统计方法学 · 统计学 2022-05-12 Chan Park , Hyunseung Kang

Multi-regional clinical trials (MRCTs) are central to global drug development, enabling evaluation of treatment effects across diverse populations. A key challenge is valid and efficient inference for a region-specific estimand when the…

统计方法学 · 统计学 2026-02-04 Chenxi Li , Ke Zhu , Shu Yang , Xiaofei Wang

We consider the problem of estimating the average treatment effect (ATE) when both randomized control trial (RCT) data and external real-world data (RWD) are available. We decompose the ATE estimand as the difference between a pooled-ATE…

统计方法学 · 统计学 2025-01-22 Mark van der Laan , Sky Qiu , Jens Magelund Tarp , Lars van der Laan

Gaussian Graphical Models (GGMs) are widely used to infer conditional dependence structures in high-dimensional data. However, standard precision matrix estimators are highly sensitive to data contamination, such as extreme outliers and…

应用统计 · 统计学 2026-03-25 Canruo Shen , Xintong Ji , Qiong Li , Wenzhi Yang , Xiaoping Shi

Bridging the gap between internal and external validity is crucial for heterogeneous treatment effect estimation. Randomised controlled trials (RCTs), favoured for their internal validity due to randomisation, often encounter challenges in…

统计方法学 · 统计学 2026-04-03 Evangelos Dimitriou , Edwin Fong , Jens Magelund Tarp , Karla Diaz-Ordaz , Brieuc Lehmann

This paper extends difference-in-differences to settings with continuous treatments. Specifically, the average treatment effect on the treated (ATT) at any level of treatment intensity is identified under a conditional parallel trends…

计量经济学 · 经济学 2026-01-05 Lucas Z. Zhang

Randomized controlled trials (RCTs) are the gold standard for evaluating causal effects but are often costly and difficult to scale; consequently, they are frequently augmented with auxiliary external controls in many applications. Prior…

统计方法学 · 统计学 2026-05-28 Jiawei Shan , Yiteng Tu , Guanbo Wang , Chao Ying , Jiwei Zhao

Recent development in the data-driven decision science has seen great advances in individualized decision making. Given data with individual covariates, treatment assignments and outcomes, policy makers best individualized treatment rule…

机器学习 · 统计学 2020-06-29 Weibin Mo , Zhengling Qi , Yufeng Liu

Estimation of conditional average treatment effects (CATEs) plays an essential role in modern medicine by informing treatment decision-making at a patient level. Several metalearners have been proposed recently to estimate CATEs in an…

应用统计 · 统计学 2022-09-07 Yizhe Xu , Nikolaos Ignatiadis , Erik Sverdrup , Scott Fleming , Stefan Wager , Nigam Shah

In this paper, we consider a situation where a decision maker's (DM's) risk preference can be described by a spectral risk measure (SRM) but there is not a single SRM which can be used to represent the DM's preferences consistently.…

最优化与控制 · 数学 2023-01-06 Manlan Li , Xiaojiao Tong , Huifu Xu

Causal inference and model interpretability are gaining increasing attention, particularly in the biomedical domain. Despite recent advance, decorrelating features in nonlinear environments with human-interpretable representations remains…

机器学习 · 计算机科学 2024-11-12 Junda Wang , Weijian Li , Han Wang , Hanjia Lyu , Caroline P. Thirukumaran , Addisu Mesfin , Hong Yu , Jiebo Luo

Density ratio estimation (DRE) is a paramount task in machine learning, for its broad applications across multiple domains, such as covariate shift adaptation, causal inference, independence tests and beyond. Parametric methods for…

机器学习 · 统计学 2025-06-03 Meilin Wang , Wei Huang , Mingming Gong , Zheng Zhang

The goal of this paper is to develop distributionally robust optimization (DRO) estimators, specifically for multidimensional Extreme Value Theory (EVT) statistics. EVT supports using semi-parametric models called max-stable distributions…

机器学习 · 统计学 2024-08-02 Patrick Kuiper , Ali Hasan , Wenhao Yang , Yuting Ng , Hoda Bidkhori , Jose Blanchet , Vahid Tarokh

We present a Bayesian nonparametric model for conditional distribution estimation using Bayesian additive regression trees (BART). The generative model we use is based on rejection sampling from a base model. Typical of BART models, our…

统计方法学 · 统计学 2022-02-02 Yinpu Li , Antonio R. Linero , Jared S. Murray

Local decision rules are commonly understood to be more explainable, due to the local nature of the patterns involved. With numerical optimization methods such as gradient boosting, ensembles of local decision rules can gain good predictive…

机器学习 · 计算机科学 2025-08-27 Xin Du , Subramanian Ramamoorthy , Wouter Duivesteijn , Jin Tian , Mykola Pechenizkiy

We introduce a discriminative regression approach to supervised classification in this paper. It estimates a representation model while accounting for discriminativeness between classes, thereby enabling accurate derivation of categorical…

机器学习 · 计算机科学 2020-01-01 Chong Peng , Qiang Cheng

Solving mathematical problems requires advanced reasoning abilities and presents notable challenges for large language models. Previous works usually synthesize data from proprietary models to augment existing datasets, followed by…

计算与语言 · 计算机科学 2024-12-24 Yuxuan Tong , Xiwen Zhang , Rui Wang , Ruidong Wu , Junxian He

In safety-critical applications data-driven models must not only be accurate but also provide reliable uncertainty estimates. This property, commonly referred to as calibration, is essential for risk-aware decision-making. In regression a…

机器学习 · 计算机科学 2026-04-23 Jelke Wibbeke , Nico Schönfisch , Sebastian Rohjans , Andreas Rauh

Average treatment effect estimation is the most central problem in causal inference with application to numerous disciplines. While many estimation strategies have been proposed in the literature, the statistical optimality of these methods…

机器学习 · 统计学 2025-06-10 Jikai Jin , Vasilis Syrgkanis