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Background. The Expected Value of Sample Information (EVSI) measures the expected benefits that could be obtained by collecting additional data. Estimating EVSI using the traditional nested Monte Carlo method is computationally expensive…

统计方法学 · 统计学 2024-02-01 Linke Li , Hawre Jalal , Anna Heath

Investing efficiently in future research to improve policy decisions is an important goal. Expected Value of Sample Information (EVSI) can be used to select the specific design and sample size of a proposed study by assessing the benefit of…

The effective sample size (ESS) is widely used in sample-based simulation methods for assessing the quality of a Monte Carlo approximation of a given distribution and of related integrals. In this paper, we revisit the approximation of the…

统计计算 · 统计学 2022-04-14 Víctor Elvira , Luca Martino , Christian P. Robert

Estimating the effective sample size (ESS) of a prior distribution is an age-old yet pivotal challenge, with great implications for clinical trials and various biomedical applications. Although numerous endeavors have been dedicated to this…

统计方法学 · 统计学 2025-07-23 Han Wang , Yan Dora Zhang , Guosheng Yin

The Expected Value of Sample Information (EVSI) is used to calculate the economic value of a new research strategy. While this value would be important to both researchers and funders, there are very few practical applications of the EVSI.…

统计理论 · 数学 2017-09-08 Anna Heath , Ioanna Manolopoulou , Gianluca Baio

Determining the sample size of an experiment can be challenging, even more so when incorporating external information via a prior distribution. Such information is increasingly used to reduce the size of the control group in randomized…

应用统计 · 统计学 2019-07-10 Beat Neuenschwander , Sebastian Weber , Heinz Schmidli , Anthony O'Hagan

Background: The Expected Value of Sample Information (EVSI) determines the economic value of any future study with a specific design aimed at reducing uncertainty in a health economic model. This has potential as a tool for trial design;…

统计方法学 · 统计学 2018-04-26 Anna Heath , Ioanna Manolopoulou , Gianluca Baio

The Effective Sample Size (ESS) is an important measure of efficiency of Monte Carlo methods such as Markov Chain Monte Carlo (MCMC) and Importance Sampling (IS) techniques. In the IS context, an approximation $\widehat{ESS}$ of the…

统计计算 · 统计学 2016-09-27 L. Martino , V. Elvira , F. Louzada

In designing external validation studies of clinical prediction models, contemporary sample size calculation methods are based on the frequentist inferential paradigm. One of the widely reported metrics of model performance is net benefit…

应用统计 · 统计学 2025-02-28 Mohsen Sadatsafavi , Andrew J Vickers , Tae Yoon Lee , Paul Gustafson , Laure Wynants

Risk prediction models are often advertised as deterministic functions that map covariates to predicted risks. However, they are typically trained using finite samples, and as such, their predictions are inherently uncertain. This…

统计方法学 · 统计学 2025-06-03 Abdollah Safari , Paul Gustafson , Mohsen Sadatsafavi

Objective: The Expected Value of Sample Information (EVSI) quantifies the economic benefit of reducing uncertainty in a health economic model by collecting additional information. This has the potential to improve the allocation of research…

统计方法学 · 统计学 2018-04-26 Anna Heath , Gianluca Baio

The Expected Value of Perfect Partial Information (EVPPI) is a decision-theoretic measure of the "cost" of parametric uncertainty in decision making used principally in health economic decision making. Despite this decision-theoretic…

应用统计 · 统计学 2016-11-07 Anna Heath , Ioanna Manolopoulou , Gianluca Baio

Background: The Expected Value of Sample Information (EVSI) calculates the value of collecting additional information through a study with a given design. Standard EVSI analyses assume that the treatment recommendations based on the new…

统计方法学 · 统计学 2021-05-14 Anna Heath

Gaussian process regression is a powerful Bayesian nonlinear regression method. Recent research has enabled the capture of many types of observations using non-Gaussian likelihoods. To deal with various tasks in spatial modeling, we benefit…

机器学习 · 统计学 2025-08-26 Yuta Shikuri

Objectives: Value of information (VOI) analyses can help policy-makers make informed decisions about whether to conduct and how to design future studies. Historically, a computationally expensive method to compute the Expected Value of…

With the robust uptick in the applications of Bayesian external data borrowing, eliciting a prior distribution with the proper amount of information becomes increasingly critical. The prior effective sample size (ESS) is an intuitive and…

统计方法学 · 统计学 2024-04-23 Hongtao Zhang , Keaven M Anderson , Zachary Zimmer , Gregory Golm , Aditi Sapre , Joseph G Ibrahim

The declining response rates in probability surveys along with the widespread availability of unstructured data has led to growing research into non-probability samples. Existing robust approaches are not well-developed for non-Gaussian…

统计方法学 · 统计学 2022-03-29 Ali Rafei , Michael R. Elliott , Carol A. C. Flannagan

Estimating mutual information (MI) from samples is a fundamental problem in statistics, machine learning, and data analysis. Recently it was shown that a popular class of non-parametric MI estimators perform very poorly for strongly…

信息论 · 计算机科学 2016-02-18 Shuyang Gao , Greg Ver Steeg , Aram Galstyan

We consider a Bayesian framework for estimating the sample size of a clinical trial. The new approach, called BESS, is built upon three pillars: Sample size of the trial, Evidence from the observed data, and Confidence of the final decision…

统计方法学 · 统计学 2026-01-21 Dehua Bi , Yuan Ji

In this work, we analyze alternative effective sample size (ESS) metrics for importance sampling algorithms, and discuss a possible extended range of applications. We show the relationship between the ESS expressions used in the literature…

统计理论 · 数学 2026-02-27 L. Martino , V. Elvira
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