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Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

图像与视频处理 · 电气工程与系统科学 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

Electroanatomical mapping, a keystone diagnostic tool in cardiac electrophysiology studies, can provide high-density maps of the local electric properties of the tissue. It is therefore tempting to use such data to better individualize…

最优化与控制 · 数学 2021-02-03 Thomas Grandits , Simone Pezzuto , Jolijn M. Lubrecht , Thomas Pock , Gernot Plank , Rolf Krause

The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…

图像与视频处理 · 电气工程与系统科学 2021-11-10 Jan Christoph , Jan Lebert

Personalized cardiac mechanics modeling is a powerful tool for understanding the biomechanics of cardiac function in health and disease and assisting in treatment planning. However, current models are limited to using medical images…

医学物理 · 物理学 2024-04-09 Lei Shi , Ian Chen , Hiroo Takayama , Vijay Vedula

Inverse design of morphing slender structures with programmable curvature has significant applications in various engineering fields. Most existing studies formulate it as an optimization problem, which requires repeatedly solving the…

软凝聚态物质 · 物理学 2025-08-28 JiaHao Li , Weicheng Huang , YinBo Zhu , Luxia Yu , Xiaohao Sun , Mingchao Liu , HengAn Wu

We introduce and study a new inverse problem for antiplane shear in elastic bodies with strain-gradient interfaces. The setting is a homogeneous isotropic elastic body containing an inclusion separated by a thin interface endowed with…

偏微分方程分析 · 数学 2025-09-19 Govanni Granados , Jeremy L. Marzuola , Casey Rodriguez

Noninvasive reconstruction of cardiac transmembrane potential (TMP) from surface electrocardiograms (ECG) involves an ill-posed inverse problem. Model-constrained regularization is powerful for incorporating rich physiological knowledge…

图像与视频处理 · 电气工程与系统科学 2019-05-14 Sandesh Ghimire , Jwala Dhamala , Prashnna Kumar Gyawali , John L Sapp , B. Milan Horacek , Linwei Wang

Physics-informed neural networks have emerged as a powerful tool in the scientific machine learning community, with applications to both forward and inverse problems. While they have shown considerable empirical success, significant…

最优化与控制 · 数学 2025-12-11 Federica Caforio , Martin Holler , Matthias Höfler

Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the need for streamlined, accurate, and high-performance computational tools. Despite the dedicated…

In this paper we develop theoretical analysis and numerical reconstruction techniques for the solution of an inverse boundary value problem dealing with the nonlinear, time-dependent monodomain equation, which models the evolution of the…

偏微分方程分析 · 数学 2017-01-27 Elena Beretta , Cecilia Cavaterra , Maria Cristina Cerutti , Andrea Manzoni , Luca Ratti

This paper proposes a data-driven model for solving the inverse problem of electrocardiography, the mathematical problem that forms the basis of electrocardiographic imaging (ECGI). We present a conditional diffusion framework that learns a…

机器学习 · 计算机科学 2026-01-27 Ramiro Valdes Jara , Adam Meyers

Inverse design of slender elastic structures underlies a wide range of applications in computer graphics, flexible electronics, biomedical devices, and soft robotics. Traditional optimization-based approaches, however, are often orders of…

图形学 · 计算机科学 2025-12-09 Jiahao Li , Mingchao Liu , Haiyi Liang , HengAn Wu , Weicheng Huang

The article considers the nonlinear inverse problem of identifying the material parameters in viscoelastic structures based on a generalized Maxwell model. The aim is to reconstruct the model parameters from stress data acquired from a…

数值分析 · 数学 2025-03-18 Rebecca Rothermel , Thomas Schuster

Solving inverse problems in cardiac electrophysiology consists in the recovery of physiological parameters from surface electrocardiogram (ECG) measurements, a task which is often computationally unfeasible due to the severe ill-posedness…

Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…

医学物理 · 物理学 2026-03-05 Nathan Dermul , Hans Dierckx

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

医学物理 · 物理学 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

We propose FiberNet, a method to estimate \emph{in-vivo} the cardiac fiber architecture of the human atria from multiple catheter recordings of the electrical activation. Cardiac fibers play a central role in the electro-mechanical function…

图像与视频处理 · 电气工程与系统科学 2022-07-25 Carlos Ruiz Herrera , Thomas Grandits , Gernot Plank , Paris Perdikaris , Francisco Sahli Costabal , Simone Pezzuto

Electrocardiographic imaging (ECGI) seeks to reconstruct cardiac electrical activity from body-surface potentials noninvasively. However, the associated inverse problem is severely ill-posed and requires robust regularization. While…

Deep neural networks have shown great potential in image reconstruction problems in Euclidean space. However, many reconstruction problems involve imaging physics that are dependent on the underlying non-Euclidean geometry. In this paper,…

图像与视频处理 · 电气工程与系统科学 2022-10-07 Xiajun Jiang , Sandesh Ghimire , Jwala Dhamala , Zhiyuan Li , Prashnna Kumar Gyawali , Linwei Wang

The study of pathological cardiac conditions such as arrhythmias, a major cause of mortality in heart failure, is becoming increasingly informed by computational simulation, numerically modelling the governing equations. This can provide…

计算工程、金融与科学 · 计算机科学 2014-06-09 Nathan Kirk , Alan Benson , Christopher Goodyer , Matthew Hubbard
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