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Conventional hematoxylin-eosin (H&E) staining is limited to revealing cell morphology and distribution, whereas immunohistochemical (IHC) staining provides precise and specific visualization of protein activation at the molecular level.…

图像与视频处理 · 电气工程与系统科学 2024-07-30 Fuqiang Chen , Ranran Zhang , Boyun Zheng , Yiwen Sun , Jiahui He , Wenjian Qin

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Yunheng Wu , Wenqi Huang , Liangyi Wang , Masahiro Oda , Yuichiro Hayashi , Daniel Rueckert , Kensaku Mori

Wireless Capsule Endoscopy (WCE) is relatively a new technology to examine the entire GI trace. During an examination, it captures more than 55,000 frames. Reviewing all these images is time-consuming and prone to human error. It has been a…

计算机视觉与模式识别 · 计算机科学 2017-11-20 Omid Haji Maghsoudi

Conventional haematoxylin, eosin and saffron (HES) histopathology, currently the gold-standard for pathological diagnosis of cancer, requires extensive sample preparations that are achieved within time scales that are not compatible with…

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Chemical staining methods are dependable but require extensive time, expensive chemicals, and raise environmental concerns. These challenges highlight the need for alternative solutions like virtual staining, which accelerates the…

图像与视频处理 · 电气工程与系统科学 2024-07-02 Mehdi Ounissi , Ilias Sarbout , Jean-Pierre Hugot , Christine Martinez-Vinson , Dominique Berrebi , Daniel Racoceanu

Paper-intensive industries like insurance, law, and government have long leveraged optical character recognition (OCR) to automatically transcribe hordes of scanned documents into text strings for downstream processing. Even in 2019, there…

计算机视觉与模式识别 · 计算机科学 2020-01-17 W. Ronny Huang , Yike Qi , Qianqian Li , Jonathan Degange

Skin Segmentation is widely used in biometric applications such as face detection, face recognition, face tracking, and hand gesture recognition. However, several challenges such as nonlinear illumination, equipment effects, personal…

计算机视觉与模式识别 · 计算机科学 2017-01-23 Mohammad Reza Mahmoodi

Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological techniques require substantial sample processing prior to…

医学物理 · 物理学 2021-07-14 Benjamin Ecclestone , Deepak Dinakaran , Parsin Haji Reza

Histopathology whole slide images (WSIs) are being widely used to develop deep learning-based diagnostic solutions, especially for precision oncology. Most of these diagnostic softwares are vulnerable to biases and impurities in the…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Abhijeet Patil , Harsh Diwakar , Jay Sawant , Nikhil Cherian Kurian , Subhash Yadav , Swapnil Rane , Tripti Bameta , Amit Sethi

Digital pathology has made significant advances in tumor diagnosis and segmentation, but image variability due to differences in organs, tissue preparation, and acquisition - known as domain shift - limits the effectiveness of current…

图像与视频处理 · 电气工程与系统科学 2024-09-23 Ho Heon Kim , Won Chan Jeong , Young Shin Ko , Young Jin Park

Volumetric lesion segmentation from computed tomography (CT) images is a powerful means to precisely assess multiple time-point lesion/tumor changes. However, because manual 3D segmentation is prohibitively time consuming, current practices…

计算机视觉与模式识别 · 计算机科学 2018-07-04 Jinzheng Cai , Youbao Tang , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

Prostate cancer (PCa) is graded by pathologists by examining the architectural pattern of cancerous epithelial tissue on hematoxylin and eosin (H&E) stained slides. Given the importance of gland morphology, automatically differentiating…

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

计算机视觉与模式识别 · 计算机科学 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

High-quality whole-slide scanning is expensive, complex, and time-consuming, thus limiting the acquisition and utilization of high-resolution histopathology images in daily clinical work. Deep learning-based single-image super-resolution…

图像与视频处理 · 电气工程与系统科学 2024-11-08 Minghong Duan , Linhao Qu , Zhiwei Yang , Manning Wang , Chenxi Zhang , Zhijian Song

Angiogenesis is a key phenomenon for tumour progression, diagnosis and treatment in brain tumours and more generally in oncology. Presently, its precise, direct quantitative assessment can only be done on whole tissue sections immunostained…

组织与器官 · 定量生物学 2017-09-08 Christophe Deroulers , Volodia Dangouloff-Ros , Mathilde Badoual , Pascale Varlet , Nathalie Boddaert

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

The expanding adoption of digital pathology has enabled the curation of large repositories of histology whole slide images (WSIs), which contain a wealth of information. Similar pathology image search offers the opportunity to comb through…

计算机视觉与模式识别 · 计算机科学 2021-07-30 Chengkuan Chen , Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Andrew J. Schaumberg , Faisal Mahmood

In this paper, we introduced a novel feature extraction approach, named exclusive autoencoder (XAE), which is a supervised version of autoencoder (AE), able to largely improve the performance of nucleus detection and classification on…

计算机视觉与模式识别 · 计算机科学 2018-11-29 Chao-Hui Huang , Daniel Racoceanu