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This study introduces a new framework for the artificial intelligence-assisted characterization of Gram-stained whole-slide images (WSIs). As a test for the diagnosis of bloodstream infections, Gram stains provide critical early data to…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Jack McMahon , Naofumi Tomita , Elizabeth S. Tatishev , Adrienne A. Workman , Cristina R Costales , Niaz Banaei , Isabella W. Martin , Saeed Hassanpour

Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…

计算机视觉与模式识别 · 计算机科学 2020-07-30 Xiaohang Fu , Tong Liu , Zhaohan Xiong , Bruce H. Smaill , Martin K. Stiles , Jichao Zhao

In this paper, we propose a novel method for highly efficient follicular segmentation of thyroid cytopathological WSIs. Firstly, we propose a hybrid segmentation architecture, which integrates a classifier into Deeplab V3 by adding a…

计算机视觉与模式识别 · 计算机科学 2019-02-15 Siyan Tao , Yao Guo , Chuang Zhu , Huang Chen , Yue Zhang , Jie Yang , Jun Liu

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…

计算机视觉与模式识别 · 计算机科学 2016-12-13 Jianxu Chen , Chukka Srinivas

Hyperspectral Imaging (HSI) combines microscopy and spectroscopy to assess the spatial distribution of spectroscopically active compounds in objects, and has diverse applications in food quality control, pharmaceutical processes, and waste…

图像与视频处理 · 电气工程与系统科学 2023-08-30 Mahdiyeh Ghaffari , Mickey C. J. Lukkien , Nematollah Omidikia , Gerjen H. Tinnevelt , Marcel C. P. van Eijk , Jeroen J. Jansen

Due to recent advances in technology, digitized histopathology images are now widely available for both clinical and research purposes. Accordingly, research into computerized image analysis algorithms for digital histopathology images has…

图像与视频处理 · 电气工程与系统科学 2020-04-01 Alison K. Cheeseman , Hamid R. Tizhoosh , Edward R. Vrscay

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

Whole Slide Images (WSIs) provide exceptional detail for studying tissue architecture at the cell level. To study tumour microenvironment (TME) with the context of various protein biomarkers and cell sub-types, analysis and registration of…

计算机视觉与模式识别 · 计算机科学 2024-04-29 Adith Jeyasangar , Abdullah Alsalemi , Shan E Ahmed Raza

In digital pathology, the traditional method for deep learning-based image segmentation typically involves a two-stage process: initially segmenting high-resolution whole slide images (WSI) into smaller patches (e.g., 256x256, 512x512,…

图像与视频处理 · 电气工程与系统科学 2024-07-04 Yucheng Tang , Yufan He , Vishwesh Nath , Pengfeig Guo , Ruining Deng , Tianyuan Yao , Quan Liu , Can Cui , Mengmeng Yin , Ziyue Xu , Holger Roth , Daguang Xu , Haichun Yang , Yuankai Huo

Surgical instrument segmentation (SIS) on endoscopic images stands as a long-standing and essential task in the context of computer-assisted interventions for boosting minimally invasive surgery. Given the recent surge of deep learning…

计算机视觉与模式识别 · 计算机科学 2024-11-08 Mingyu Sheng , Jianan Fan , Dongnan Liu , Ron Kikinis , Weidong Cai

Histopathological examination of surgical biopsies, such as in glioma and glioblastoma resection, is hindered in current clinical practice by the long times required for the laboratory analysis and pathological screening, typically taking…

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Purpose: To present a high-performing, robust, and flexible deep learning pipeline for automatic segmentation of 30 organs-at-risk (OARs) in head and neck (H&N) cancer patients, using MRI, CT, or both. Method: We trained a segmentation…

图像与视频处理 · 电气工程与系统科学 2025-09-08 Sébastien Quetin , Andrew Heschl , Mauricio Murillo , Rohit Murali , Piotr Pater , George Shenouda , Shirin A. Enger , Farhad Maleki

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Tissue segmentation is an important pre-requisite for efficient and accurate diagnostics in digital pathology. However, it is well known that whole-slide scanners can fail in detecting all tissue regions, for example due to the tissue type,…

计算机视觉与模式识别 · 计算机科学 2017-04-04 Péter Bándi , Rob van de Loo , Milad Intezar , Daan Geijs , Francesco Ciompi , Bram van Ginneken , Jeroen van der Laak , Geert Litjens

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

图像与视频处理 · 电气工程与系统科学 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Mycosis fungoides (MF) is a rare, potentially life threatening skin disease, which in early stages clinically and histologically strongly resembles Eczema, a very common and benign skin condition. In order to increase the survival rate, one…

图像与视频处理 · 电气工程与系统科学 2020-09-14 Jérémy Scheurer , Claudio Ferrari , Luis Berenguer Todo Bom , Michaela Beer , Werner Kempf , Luis Haug

Histopathology is a gold standard for cancer diagnosis under a microscopic examination. However, histological tissue processing procedures result in artifacts, which are ultimately transferred to the digitized version of glass slides, known…

Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

计算机视觉与模式识别 · 计算机科学 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot

Retinal image segmentation plays an important role in automatic disease diagnosis. This task is very challenging because the complex structure and texture information are mixed in a retinal image, and distinguishing the information is…

图像与视频处理 · 电气工程与系统科学 2020-08-04 Shihao Zhang , Huazhu Fu , Yanwu Xu , Yanxia Liu , Mingkui Tan