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It is widely acknowledged that the biomedical literature suffer from a surfeit of false positive results. Part of the reason for this is the persistence of the myth that observation of a p value less than 0.05 is sufficient justification to…

应用统计 · 统计学 2019-03-28 David Colquhoun

Integrative analyses based on statistically relevant associations between genomics and a wealth of intermediary phenotypes (such as imaging) provide vital insights into their clinical relevance in terms of the disease mechanisms. Estimates…

Lack of repeatability and generalisability are two significant threats to continuing scientific development in Natural Language Processing. Language models and learning methods are so complex that scientific conference papers no longer…

计算与语言 · 计算机科学 2018-08-07 Andrew Moore , Paul Rayson

Statisticians often face the choice between using probability models or a paradigm defined by minimising a loss function. Both approaches are useful and, if the loss can be re-cast into a proper probability model, there are many tools to…

统计方法学 · 统计学 2022-03-29 Jack Jewson , David Rossell

The goal of this paper is to provide a theory linear regression based entirely on approximations. It will be argued that the standard linear regression model based theory whether frequentist or Bayesian has failed and that this failure is…

统计方法学 · 统计学 2024-02-16 Laurie Davies

Bayesian statistics has gained popularity in psychological research due to its intuitive uncertainty quantification and convenient information-updating rules. In many applications, however, prior distributions are introduced merely as…

统计方法学 · 统计学 2026-03-10 Yang Liu , Jonathan P. Williams , Jan Hannig

The logistic specification has been used extensively in non-Bayesian statistics to model the dependence of discrete outcomes on the values of specified covariates. Because the likelihood function is globally weakly concave estimation by…

统计计算 · 统计学 2013-04-17 John Geweke , Garland Durham , Huaxin Xu

Indirect inference (II) is a methodology for estimating the parameters of an intractable (generative) model on the basis of an alternative parametric (auxiliary) model that is both analytically and computationally easier to deal with. Such…

统计方法学 · 统计学 2015-05-14 Christopher C. Drovandi , Anthony N. Pettitt , Anthony Lee

When interpreting A/B tests, we typically focus only on the statistically significant results and take them by face value. This practice, termed post-selection inference in the statistical literature, may negatively affect both point…

应用统计 · 统计学 2021-06-01 Alex Deng , Yicheng Li , Jiannan Lu , Vivek Ramamurthy

This paper provides a critical review of the Bayesian perspective of causal inference based on the potential outcomes framework. We review the causal estimands, identification assumptions, the general structure of Bayesian inference of…

统计方法学 · 统计学 2022-10-25 Fan Li , Peng Ding , Fabrizia Mealli

Randomization inference is a widely-used and appealing approach for analyzing treatment effects in randomized experiments, as it is finite-sample valid and does not require any distributional assumptions. However, naive application of…

计量经济学 · 经济学 2026-05-12 Xinran Li , Peizan Sheng , Zeyang Yu

The issue of combining individual $p$-values to aggregate multiple small effects is prevalent in many scientific investigations and is a long-standing statistical topic. Many classical methods are designed for combining independent and…

统计方法学 · 统计学 2021-09-08 Yusi Fang , George C. Tseng , Chung Chang

Discrete state spaces represent a major computational challenge to statistical inference, since the computation of normalisation constants requires summation over large or possibly infinite sets, which can be impractical. This paper…

统计方法学 · 统计学 2023-09-04 Takuo Matsubara , Jeremias Knoblauch , François-Xavier Briol , Chris. J. Oates

Estimation of the population size $n$ from $k$ i.i.d.\ binomial observations with unknown success probability $p$ is relevant to a multitude of applications and has a long history. Without additional prior information this is a notoriously…

Selective inference (SI) has been actively studied as a promising framework for statistical hypothesis testing for data-driven hypotheses. The basic idea of SI is to make inferences conditional on an event that a hypothesis is selected. In…

机器学习 · 统计学 2023-12-29 Tomohiro Shiraishi , Daiki Miwa , Vo Nguyen Le Duy , Ichiro Takeuchi

Combining dependent p-values poses a long-standing challenge in statistical inference, particularly when aggregating findings from multiple methods to enhance signal detection. Recently, p-value combination tests based on regularly…

统计方法学 · 统计学 2025-04-22 Lin Gui , Yuchao Jiang , Jingshu Wang

We introduce equivalence testing procedures for linear regression analyses. Such tests can be very useful for confirming the lack of a meaningful association between a continuous outcome and a continuous or binary predictor. Specifically,…

统计方法学 · 统计学 2023-05-17 Harlan Campbell

Probabilistic modeling is fundamental to the statistical analysis of complex data. In addition to forming a coherent description of the data-generating process, probabilistic models enable parameter inference about given data sets. This…

种群与进化 · 定量生物学 2018-05-01 Branden J. Olson , Frederick A. Matsen

Combining individual p-values to aggregate multiple small effects has a long-standing interest in statistics, dating back to the classic Fisher's combination test. In modern large-scale data analysis, correlation and sparsity are common…

统计方法学 · 统计学 2018-11-30 Yaowu Liu , Jun Xie

Structural equation models and Bayesian networks have been widely used to study causal relationships between continuous variables. Recently, a non-Gaussian method called LiNGAM was proposed to discover such causal models and has been…

机器学习 · 统计学 2010-06-23 Yusuke Komatsu , Shohei Shimizu , Hidetoshi Shimodaira