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We used a spatially explicit agent-based model of SARS-CoV-2 transmission combined with spatially fine-grained COVID-19 observation data from Public Health Scotland to investigate the initial rise of the Omicron (BA.1) variant of concern.…

种群与进化 · 定量生物学 2024-12-02 Christopher J. Banks , Ewan Colman , Anthony Wood , Thomas Doherty , Rowland R. Kao

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

种群与进化 · 定量生物学 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

During its first two years, the SARS-CoV-2 pandemic manifested as multiple waves shaped by complex interactions between variants of concern, non-pharmaceutical interventions, and the immunological landscape of the population. Understanding…

物理与社会 · 物理学 2022-12-29 Otilia Boldea , Amir Alipoor , Sen Pei , Jeffrey Shaman , Ganna Rozhnova

Although previous infection and vaccination provide protection against SARS-CoV-2 infection, both reinfection and breakthrough infection are possible events whose occurrence would increase with time after first exposure to the antigen and…

种群与进化 · 定量生物学 2022-06-07 Ariel Félix Gualtieri , Carolina de la Cal , Augusto Francisco Toma , Pedro Hecht

Several SARS-CoV-2 variants that evolved during the COVID-19 pandemic have appeared to differ in severity, based on analyses of single-country datasets. With decreased SARS-CoV-2 testing and sequencing, international collaborative studies…

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

种群与进化 · 定量生物学 2026-03-31 J. Ilnytskyi , T. Patsahan

The COVID-19 outbreak resulted in multiple waves of infections that have been associated with different SARS-CoV-2 variants. Studies have reported differential impact of the variants on respiratory health of patients. We explore whether…

The COVID-19 pandemic has given rise to numerous articles from different scientific fields (epidemiology, virology, immunology, airflow physics...) without any effort to link these different insights. In this review, we aim to establish…

种群与进化 · 定量生物学 2023-01-31 Florian Poydenot , Alice Lebreton , Jacques Haiech , Bruno Andreotti

Previous pandemics, including influenza pandemics and Covid-19, have disproportionately impacted M\=aori and Pacific populations in Aotearoa New Zealand. The reasons for this are multi-faceted, including differences in socioeconomic…

种群与进化 · 定量生物学 2026-03-24 Samik Datta , Vincent X Lomas , Nicole Satherley , Andrew Sporle , Michael J Plank

Since December 2020, variants of COVID-19 (especially Delta and Omicron) appeared with different characteristics that influenced death and transmissibility emerged around the world. To address the novel dynamics of the disease, we propose a…

种群与进化 · 定量生物学 2022-01-19 Sarita Bugalia , Jai Prakash Tripathi , Hao Wang

Background: During 2021 several new variants of the SARS-CoV-2 virus appeared with both increased levels of transmissibility and virulence with respect to the original wild variant. The Delta (B.1.617.2) variation, first seen in India,…

物理与社会 · 物理学 2021-08-17 William A. Barletta

The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize vaccine deployment, and develop new antiviral therapies to combat…

种群与进化 · 定量生物学 2021-12-21 Rajat Desikan , Pranesh Padmanabhan , Andrzej M. Kierzek , Piet H. van der Graaf

The crisis caused by the COVID-19 outbreak around the globe raised an increasing concern about the ongoing emergence of variants of SARS-CoV-2 that may evade the immune response provided by vaccines. New variants appear due to mutation, and…

种群与进化 · 定量生物学 2022-12-14 M. Ahumada , A. Ledesma-Araujo , Leonardo Gordillo , Juan F. Marín

Despite the progress in medical care, combined population-wide interventions (such as physical distancing, testing and contact tracing) are still crucial to manage the SARS-CoV-2 pandemic, aggravated by the emergence of new highly…

The COVID-19 pandemic has profoundly affected global health, driven by the remarkable transmissibility and mutational adaptability of the SARS-CoV-2 virus. Although five variants of concern, Alpha, Beta, Gamma, Delta, and Omicron, have been…

基因组学 · 定量生物学 2026-05-07 Bo Jing , Kai-Rui Zhang , Hong-Li Zeng , Erik Aurell

The COVID-19 pandemic has placed unprecedented demands on local public health units in Ontario, Canada, one of which was the need for in-house epidemiological-modelling capabilities. To address this need, Ontario Tech University and the…

种群与进化 · 定量生物学 2022-11-10 Eleodor Nichita , Mary-Anne Pietrusiak , Fangli Xie , Peter Schwanke , Anjali Pandya

As of December 2020, the COVID-19 pandemic has infected over 75 million people, making it the deadliest pandemic in modern history. This study develops a novel compartmental epidemiological model specific to the SARS-CoV-2 virus and…

种群与进化 · 定量生物学 2021-11-19 Caden Lin

The effectiveness of the first and second dose vaccinations are different for COVID-19; therefore, a susceptible-infected-recovered-vaccination1-vaccination2-death (SIRVVD) model that can represent the states of the first and second…

种群与进化 · 定量生物学 2022-05-02 Yuto Omae , Makoto Sasaki , Jun Toyotani , Kazuyuki Hara , Hirotaka Takahashi

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), has led to the deepest global health and economic crisis of the current century. This dramatic situation has forced the…

应用统计 · 统计学 2021-10-22 Álvaro Briz-Redón , Ángel Serrano-Aroca

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

动力系统 · 数学 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom
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