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Unmeasured confounding is one of the major concerns in causal inference from observational data. Proximal causal inference (PCI) is an emerging methodological framework to detect and potentially account for confounding bias by carefully…

统计方法学 · 统计学 2025-04-24 Kendrick Li , George C. Linderman , Xu Shi , Eric J. Tchetgen Tchetgen

Prudent management of insurance investment portfolios requires competent asset pricing of fixed-income assets with time-to-event contingent cash flows, such as consumer asset-backed securities (ABS). Current market pricing techniques for…

风险管理 · 定量金融 2023-02-27 Jackson P. Lautier , Vladimir Pozdnyakov , Jun Yan

The predictiveness curve is a valuable tool for predictive evaluation, risk stratification, and threshold selection in a target population, given a single biomarker or a prediction model. In the presence of competing risks, regression…

统计方法学 · 统计学 2025-08-04 Wei Tao , Jing Ning , Wen Li , Wenyaw Chan , Xi Luo , Ruosha Li

In this paper the regression discontinuity design is adapted to the survival analysis setting with right-censored data, studied in an intensity based counting process framework. In particular, a local polynomial regression version of the…

统计方法学 · 统计学 2022-10-07 Emil Aas Stoltenberg

Precision medicine leverages patient heterogeneity to estimate individualized treatment regimens, formalized, data-driven approaches designed to match patients with optimal treatments. In the presence of competing events, where multiple…

统计方法学 · 统计学 2024-11-14 Christina W. Zhou , Nikki L. B. Freeman , Katharine L. McGinigle , Michael R. Kosorok

Prediction of time-to-event data often suffers from rare event rates, small sample sizes, high dimensionality and low signal-to-noise ratios. Incorporating published prediction models from large-scale studies is expected to improve the…

统计方法学 · 统计学 2022-08-01 Di Wang , Wen Ye , Randall Sung , Hui Jiang , Jeremy M. G. Taylor , Lisa Ly , Kevin He

Many applications involve reasoning about time durations before a critical event happens--also called time-to-event outcomes. When will a customer cancel a subscription, a coma patient wake up, or a convicted criminal reoffend?…

机器学习 · 统计学 2024-10-03 George H. Chen

We develop a simulation tool to support policy-decisions about healthcare for chronic diseases in defined populations. Incident disease-cases are generated in-silico from an age-sex characterised general population using standard…

应用统计 · 统计学 2010-09-03 Nathan Green , Duncan Smith , Matthew Sperrin , Iain Buchan

Since survival data occur over time, often important covariates that we wish to consider also change over time. Such covariates are referred as time-dependent covariates. Quantile regression offers flexible modeling of survival data by…

统计方法学 · 统计学 2014-05-01 Malka Gorfine , Yair Goldberg , Yaacov Ritov

Accurately predicting hospital length-of-stay at the time a patient is admitted to hospital may help guide clinical decision making and resource allocation. In this study we aim to build a decision support system that predicts hospital…

人工智能 · 计算机科学 2023-08-08 Mucahit Cevik , Can Kavaklioglu , Fahad Razak , Amol Verma , Ayse Basar

In this paper I describe some substantial extensions to the survsim command for simulating survival data. survsim can now simulate survival data from a parametric distribution, a custom/user-defined distribution, from a fitted merlin model,…

统计计算 · 统计学 2021-10-22 Michael J. Crowther

This article proposes a method for measuring the latent risks involved in the recovery process of non performing loans in financial institutions and business firms that deal with collection and recovery processes. To that end, we apply the…

应用统计 · 统计学 2014-08-20 Mauro R. Oliveira , Francisco Louzada

The use of observational time series data to assess the impact of multi-time point interventions is becoming increasingly common as more health and activity data are collected and digitized via wearables, social media, and electronic health…

统计方法学 · 统计学 2020-12-01 Roy Adams , Suchi Saria , Michael Rosenblum

Competing risk data appear widely in modern biomedical research. Cause-specific hazard models are often used to deal with competing risk data in the past two decades. There is no current study on the kernel likelihood method for the…

统计方法学 · 统计学 2021-09-14 Xiaomeng Qi , Zhangsheng Yu

In this paper, a competing risks model is analyzed based on improved adaptive type-II progressive censored sample (IAT-II PCS). Two independent competing causes of failures are considered. It is assumed that lifetimes of the competing…

统计方法学 · 统计学 2023-02-20 Subhankar Dutta , Suchandan Kayal

Applications of machine learning in healthcare often require working with time-to-event prediction tasks including prognostication of an adverse event, re-hospitalization or death. Such outcomes are typically subject to censoring due to…

机器学习 · 计算机科学 2022-08-04 Chirag Nagpal , Willa Potosnak , Artur Dubrawski

Models for predicting the time of a future event are crucial for risk assessment, across a diverse range of applications. Existing time-to-event (survival) models have focused primarily on preserving pairwise ordering of estimated event…

机器学习 · 统计学 2021-01-14 Paidamoyo Chapfuwa , Chenyang Tao , Lawrence Carin , Ricardo Henao

Competing risks occur in survival analysis when multiple causes of death are present. They play a prominent role in several domains extending beyond biostatistics to encompass epidemiology, actuarial sciences, and reliability theory. This…

统计方法学 · 统计学 2026-04-30 Claudio Del Sole , Antonio Lijoi , Igor Prünster

Existing metrics in competing risks survival analysis such as concordance and accuracy do not evaluate a model's ability to jointly predict the event type and the event time. To address these limitations, we propose a new metric, which we…

统计方法学 · 统计学 2019-08-20 Kartik Ahuja , Mihaela van der Schaar

The generalization performance of a risk prediction model can be evaluated by its calibration, which measures the agreement between predicted and observed outcomes on external validation data. Here, methods for assessing the calibration of…

统计方法学 · 统计学 2020-01-31 Moritz Berger , Matthias Schmid