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Epidemic models are always simplifications of real world epidemics. Which real world features to include, and which simplifications to make, depend both on the disease of interest and on the purpose of the modelling. In the present paper we…

概率论 · 数学 2008-12-19 Tom Britton , David Lindenstrand

Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with…

种群与进化 · 定量生物学 2022-01-31 Jason Hindes , Michael Assaf , Ira B. Schwartz

Advances in mathematical epidemiology have led to a better understanding of the risks posed by epidemic spreading and informed strategies to contain disease spread. However, a challenge that has been overlooked is that, as a disease becomes…

物理与社会 · 物理学 2016-02-17 Lucas Böttcher , Olivia Woolley-Meza , Nuno A. M. Araújo , Hans J. Herrmann , Dirk Helbing

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

This article examines how diseases on random networks spread in time. The disease is described by a probability distribution function for the number of infected and recovered individuals, and the probability distribution is described by a…

适应与自组织系统 · 物理学 2013-05-29 M. Marder

The importation and subsequent establishment of novel pathogenic strains in a population is subject to a large degree of uncertainty due to the stochastic nature of the disease dynamics. Mathematical models need to take this stochasticity…

种群与进化 · 定量生物学 2024-12-02 Jacob Curran-Sebastian , Frederik Mølkjær Andersen , Samir Bhatt

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

种群与进化 · 定量生物学 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey

We develop a new methodology for the efficient computation of epidemic final size distributions for a broad class of Markovian models. We exploit a particular representation of the stochastic epidemic process to derive a method which is…

种群与进化 · 定量生物学 2015-01-06 Andrew J. Black , J. V. Ross

We study contact epidemic models for the spread of infective diseases in finite populations. The size dependence enters in the infection rate. The dynamics of such models is then analyzed within the deterministic approximation, as well as…

种群与进化 · 定量生物学 2020-04-07 Ph. Blanchard , S. Nicolis

This study investigates the utilization of various mathematical models for comprehending and managing outbreaks of infectious diseases, with a specific focus on how different distributions of incubation times influence predictions regarding…

适应与自组织系统 · 物理学 2024-03-08 Eric Rozan , Marcelo N Kuperman , Sebastian Bouzat

Even in large systems, the effect of noise arising from when populations are initially small can persist to be measurable on the macroscale. A deterministic approximation to a stochastic model will fail to capture this effect, but it can be…

种群与进化 · 定量生物学 2024-08-13 Dylan Morris , John Maclean , Andrew J. Black

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

动力系统 · 数学 2021-11-18 Lorenzo Zino , Ming Cao

While COVID-19 is rapidly propagating around the globe, the need for providing real-time forecasts of the epidemics pushes fits of dynamical and statistical models to available data beyond their capabilities. Here we focus on statistical…

种群与进化 · 定量生物学 2020-06-08 Tommaso Alberti , Davide Faranda

The interpretation of sampling data plays a crucial role in policy response to the spread of a disease during an epidemic, such as the COVID-19 epidemic of 2020. However, this is a non-trivial endeavor due to the complexity of real world…

种群与进化 · 定量生物学 2020-07-30 James D. Brunner , Nicholas Chia

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

种群与进化 · 定量生物学 2021-05-18 G. Albi , L. Pareschi , M. Zanella

Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

物理与社会 · 物理学 2023-01-03 Klaus Kroy

Mathematical modeling of disease spreading plays a crucial role in understanding, controlling and preventing epidemic outbreaks. In a microscopic description of the propagation of a disease over the complex network of human contacts, the…

物理与社会 · 物理学 2021-10-08 Federico Malizia , Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

The vast majority of models for the spread of communicable diseases are parametric in nature and involve underlying assumptions about how the disease spreads through a population. In this article we consider the use of Bayesian…

统计方法学 · 统计学 2017-06-12 Theodore Kypraios , Philip D. O'Neill

The dynamics of contact networks and epidemics of infectious diseases often occur on comparable time scales. Ignoring one of these time scales may provide an incomplete understanding of the population dynamics of the infection process. We…

种群与进化 · 定量生物学 2021-02-09 Luis E C Rocha , Naoki Masuda

Global strategies to contain a pandemic, such as social distancing and protective measures, are designed to reduce the overall transmission rate between individuals. Despite such measures, essential institutions, including hospitals,…

种群与进化 · 定量生物学 2022-09-07 Roberto Morán-Tovar , Henning Gruell , Florian Klein , Michael Lässig