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Serology testing can identify past infection by quantifying the immune response of an infected individual providing important public health guidance. Individual immune responses are time-dependent, which is reflected in antibody…

定量方法 · 定量生物学 2022-08-04 Prajakta Bedekar , Anthony J. Kearsley , Paul N. Patrone

Online reinforcement learning and other adaptive sampling algorithms are increasingly used in digital intervention experiments to optimize treatment delivery for users over time. In this work, we focus on longitudinal user data collected by…

机器学习 · 计算机科学 2023-04-20 Kelly W. Zhang , Lucas Janson , Susan A. Murphy

This article develops a method to construct the optimal sequential test for monitoring the changes in the distribution of finite observation sequences with a general dependence structure. This method allows us to prove that different…

统计理论 · 数学 2019-08-01 Dong Han , Fugee Tsung , Jinguo Xian

This paper introduces a novel methodology that utilizes latency to unveil time-series dependence patterns. A customized statistical test detects memory dependence in event sequences by analyzing their inter-event time distributions.…

计量经济学 · 经济学 2023-09-22 Fabio Vanni , David Lambert

In this paper, we propose a class of monitoring statistics for a mean shift in a sequence of high-dimensional observations. Inspired by the recent U-statistic based retrospective tests developed by Wang et al.(2019) and Zhang et al.(2020),…

统计方法学 · 统计学 2021-01-19 Teng Wu , Runmin Wang , Hao Yan , Xiaofeng Shao

In this paper, we study the dynamics of epidemic processes taking place in temporal and adaptive networks. Building on the activity-driven network model, we propose an adaptive model of epidemic processes, where the network topology…

社会与信息网络 · 计算机科学 2018-02-27 Masaki Ogura , Victor M. Preciado , Naoki Masuda

Devising intelligent agents able to live in an environment and learn by observing the surroundings is a longstanding goal of Artificial Intelligence. From a bare Machine Learning perspective, challenges arise when the agent is prevented…

计算机视觉与模式识别 · 计算机科学 2022-04-27 Matteo Tiezzi , Simone Marullo , Lapo Faggi , Enrico Meloni , Alessandro Betti , Stefano Melacci

Adaptive designs are increasingly used in clinical trials and online experiments to improve participant outcomes by dynamically updating treatment allocation as data accumulate. In practice, experimenters often consider multiple candidate…

统计方法学 · 统计学 2026-04-08 Wenxin Zhang , Aaron Hudson , Maya Petersen , Mark van der Laan

With the emergence and spread of infectious diseases with pandemic potential, such as COVID- 19, the urgency for vaccine development have led to unprecedented compressed and accelerated schedules that shortened the standard development…

应用统计 · 统计学 2025-04-22 Jiayue Wang , Ben Boukai

In this paper, we propose a new real-time differential virus transmission model, which can give more accurate and robust short-term predictions of COVID-19 transmitted infectious disease with benefits of near-term trend projection.…

种群与进化 · 定量生物学 2020-05-05 Sheldon X. D. Tan , Liang Chen

In the Staged Progression (SP) epidemic models, infected individuals are classified into a suitable number of states. The goal of these models is to describe as closely as possible the effect of differences in infectiousness exhibited by…

动力系统 · 数学 2024-02-08 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

The COVID-19 pandemic provided many modeling challenges to investigate the evolution of an epidemic process over areal units. A suitable encompassing model must describe the spatio-temporal variations of the disease infection rate of…

统计方法学 · 统计学 2023-11-20 Pierfrancesco Alaimo Di Loro , Dankmar Boehning , Sujit Sahu

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

统计方法学 · 统计学 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

This paper extends the canonical model of epidemiology, the SIRD model, to allow for time-varying parameters for real-time measurement and prediction of the trajectory of the Covid-19 pandemic. Time variation in model parameters is captured…

计量经济学 · 经济学 2023-02-01 Cem Cakmakli , Yasin Simsek

The COVID-19 pandemic has highlighted the need to upgrade systems for infectious disease surveillance and forecasting and modeling of the spread of infection, both of which inform evidence-based public health guidance and policies. Here, we…

Large network logs, recording multivariate time series generated from heterogeneous devices and sensors in a network, can often reveal important information about abnormal activities, such as network intrusions and device malfunctions.…

机器学习 · 计算机科学 2025-06-19 Yijun Lin , Yao-Yi Chiang

Continuously-observed event occurrences, often exhibit self- and mutually-exciting effects, which can be well modeled using temporal point processes. Beyond that, these event dynamics may also change over time, with certain periodic trends.…

机器学习 · 计算机科学 2024-03-11 Sikun Yang , Hongyuan Zha

Time-series anomaly detection deals with the problem of detecting anomalous timesteps by learning normality from the sequence of observations. However, the concept of normality evolves over time, leading to a "new normal problem", where the…

机器学习 · 计算机科学 2024-01-23 Dongmin Kim , Sunghyun Park , Jaegul Choo

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related…

物理与社会 · 物理学 2020-12-24 Matthias Pezzutto , Nicolas Bono Rossello , Luca Schenato , Emanuele Garone

The spread of an undesirable contact process, such as an infectious disease (e.g. COVID-19), is contained through testing and isolation of infected nodes. The temporal and spatial evolution of the process (along with containment through…

机器学习 · 计算机科学 2023-03-24 Xingran Chen , Hesam Nikpey , Jungyeol Kim , Saswati Sarkar , Shirin Saeedi-Bidokhti