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相关论文: On DNA Codes Over the Non-Chain Ring $\mathbb{Z}_4…

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The simplest possible informational heteropolymer requires only a two-letter alphabet to be able to store information. The evolutionary choice of four monomers in the informational biomolecules RNA/DNA or their progenitors is intriguing,…

基因组学 · 定量生物学 2022-11-17 Hemachander Subramanian

We study the problem of coded information retrieval for block-structured data, motivated by DNA-based storage systems where a database is partitioned into multiple files that must each be recoverable as an atomic unit. We initiate and…

信息论 · 计算机科学 2026-03-19 Daniella Bar-Lev

To equip DNA-based data storage with random-access capabilities, Yazdi et al. (2018) prepended DNA strands with specially chosen address sequences called primers and provided certain design criteria for these primers. We provide explicit…

信息论 · 计算机科学 2019-01-07 Yeow Meng Chee , Han Mao Kiah , Hengjia Wei

We propose generative neural network methods to generate DNA sequences and tune them to have desired properties. We present three approaches: creating synthetic DNA sequences using a generative adversarial network; a DNA-based variant of…

机器学习 · 计算机科学 2017-12-19 Nathan Killoran , Leo J. Lee , Andrew Delong , David Duvenaud , Brendan J. Frey

In this paper we study two dimensional minimal linear code over the ring $\mathbb{Z}_{p^n}$(where $p$ is prime). We show that if the generator matrix $G$ of the two dimensional linear code $M$ contains $p^n+p^{n-1}$ column vector of the…

信息论 · 计算机科学 2024-03-05 Biplab Chatterjee , Ratnesh Kumar Mishra

DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA…

生物大分子 · 定量生物学 2015-11-10 Stephanie Johnson , Martin Lindén , Rob Phillips

Linear codes over finite rings become one of hot topics in coding theory after Hommons et al.([4], 1994) discovered that several remarkable nonlinear binary codes with some linear-like properties are the images of Gray map of linear codes…

信息论 · 计算机科学 2016-03-08 Aixian Zhang , Jin Li , Keqin Feng

Recursive decoding techniques are considered for Reed-Muller (RM) codes of growing length $n$ and fixed order $r.$ An algorithm is designed that has complexity of order $n\log n$ and corrects most error patterns of weight up to…

信息论 · 计算机科学 2017-03-17 Ilya Dumer

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of…

软凝聚态物质 · 物理学 2015-06-25 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

By using the notion of $d$-embedding $\Gamma$ of a (canonical) subgeometry $\Sigma$ and of exterior set with respect to the $h$-secant variety $\Omega_{h}(\mathcal{A})$ of a subset $\mathcal{A}$, $ 0 \leq h \leq n-1$, in the finite…

信息论 · 计算机科学 2024-05-03 Nicola Durante , Giovanni Giuseppe Grimaldi , Giovanni Longobardi

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and tradeoffs of DNA-based storage systems under a simple model, motivated by current…

信息论 · 计算机科学 2017-05-16 Reinhard Heckel , Ilan Shomorony , Kannan Ramchandran , David N. C. Tse

As a possible implementation of data storage using DNA, multiple strands of DNA are stored in a liquid container so that, in the future, they can be read by an array of DNA readers in parallel. These readers will sample the strands with…

信息论 · 计算机科学 2024-09-04 Hsin-Po Wang , Venkatesan Guruswami

A linear code with parameters $[n, k, n-k+1]$ is called a maximum distance separable (MDS for short) code. A linear code with parameters $[n, k, n-k]$ is said to be almost maximum distance separable (AMDS for short). A linear code is said…

信息论 · 计算机科学 2023-07-11 Zhonghua Sun , Cunsheng Ding

DNA Polymerase is an enzyme that participates in the process of DNA replication. In general, forward DNA polymerase moves along the template strand in a 3'-5' direction, and the daughter strand is formed in a 5'-3' direction. This paper…

生物大分子 · 定量生物学 2014-09-19 Penghui Shi

In array-based DNA synthesis, multiple strands of DNA are synthesized in parallel to reduce the time cost from the sum of their lengths to the length their shortest common supersequences. To maximize the amount of information that can be…

信息论 · 计算机科学 2024-05-29 Hsin-Po Wang , Chi-Wei Chin

It is an important task to construct quantum maximum-distance-separable (MDS) codes with good parameters. In the present paper, we provide six new classes of q-ary quantum MDS codes by using generalized Reed-Solomon (GRS) codes and…

信息论 · 计算机科学 2019-12-06 Weijun Fang , Fang-Wei Fu

Early hardware limitations of GPU (lack of synchronization primitives and limited memory caching mechanisms) can make GPU-based computation inefficient. Now Bio-technologies bring more chances to Bioinformatics and Biological Engineering.…

分布式、并行与集群计算 · 计算机科学 2014-10-29 YuKun Zhong , BaoQiu Wang , JianBiao Lin , Chen Tao , Che Nian , Xie Wen

DNA nanostructures with programmable shape and interactions can be used as building blocks for the self-assembly of crystalline materials with prescribed nanoscale features, holding a vast technological potential. Structural rigidity and…

软凝聚态物质 · 物理学 2019-01-30 Ryan A. Brady , William T. Kaufhold , Nicholas J. Brooks , Vito Foderà , Lorenzo Di Michele

The paper describes an algorithm to compute a consensus sequence from a set of DNA sequences of approximatively identical length generated by 3rd sequencing generation technologies. Its purpose targets DNA storage and is guided by specific…

数据结构与算法 · 计算机科学 2021-05-12 Dominique Lavenier

Generalized quasi-cyclic (GQC) codes with arbitrary lengths over the ring $\mathbb{F}_{q}+u\mathbb{F}_{q}$, where $u^2=0$, $q=p^n$, $n$ a positive integer and $p$ a prime number, are investigated. By the Chinese Remainder Theorem,…

信息论 · 计算机科学 2013-07-09 Jian Gao , Fang-Wei Fu , Linzhi Shen