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Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

机器学习 · 计算机科学 2026-01-22 Giorgia Rigamonti , Mirko Paolo Barbato , Davide Marelli , Paolo Napoletano

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to impaired insulin production or function. Two main forms are recognized: type 1 diabetes (T1D), which involves autoimmune destruction of…

基因组学 · 定量生物学 2026-02-11 Maria De La Luz Lomboy Toledo , Daniel Onah

Type 1 Diabetes (T1D) is an autoimmune disease leading to insulin insufficiency. Thus, patients require lifelong insulin therapy, which has a side effect of hypoglycemia. Hypoglycemia is a critical state of decreased blood glucose levels…

机器学习 · 计算机科学 2026-01-21 Beyza Cinar , Louisa van den Boom , Maria Maleshkova

A database of ten type 1 diabetes patients wearing a continuous glucose monitoring device has enabled to record their blood glucose continuous variations every minute all day long during fourteen consecutive days. These recordings…

To avoid serious diabetic complications, people with type 1 diabetes must keep their blood glucose levels (BGLs) as close to normal as possible. Insulin dosages and carbohydrate consumption are important considerations in managing BGLs.…

机器学习 · 计算机科学 2021-05-19 Jeremy Beauchamp , Razvan Bunescu , Cindy Marling , Zhongen Li , Chang Liu

AI procedures joined with wearable gadgets can convey exact transient blood glucose level forecast models. Also, such models can learn customized glucose-insulin elements dependent on the sensor information gathered by observing a few parts…

机器学习 · 计算机科学 2021-01-22 Ignacio Rodriguez

Objective digital data is scarce yet needed in many domains to enable research that can transform the standard of healthcare. While data from consumer-grade wearables and smartphones is more accessible, there is critical need for similar…

计算机与社会 · 计算机科学 2023-09-20 Temiloluwa Prioleau , Abigail Bartolome , Richard Comi , Catherine Stanger

People living with Type 1 Diabetes (T1D) lose the ability to produce insulin naturally. To compensate, they inject synthetic insulin. One common way to inject insulin is through automated insulin delivery systems, which use sensors to…

密码学与安全 · 计算机科学 2024-01-04 Samuel T. King

The global diabetes epidemic highlights the importance of maintaining good glycemic control. Glucose prediction is a fundamental aspect of diabetes management, facilitating real-time decision-making. Recent research has introduced models…

人工智能 · 计算机科学 2024-04-19 Ming Cheng , Xingjian Diao , Ziyi Zhou , Yanjun Cui , Wenjun Liu , Shitong Cheng

Diabetes devices, including Continuous Glucose Monitoring (CGM), Smart Insulin Pens, and Automated Insulin Delivery systems, generate rich time-series data widely used in research and machine learning. However, inconsistent data formats…

机器学习 · 计算机科学 2026-04-15 Elliott C. Pryor , Marc D. Breton , Anas El Fathi

In type 2 diabetes (T2D) treatment, finding a safe and effective basal insulin dose is a challenge. The dose-response is highly individual and to ensure safety, people with T2D titrate by slowly increasing the daily insulin dose to meet…

系统与控制 · 电气工程与系统科学 2022-11-28 Sarah Ellinor Engell , Tinna Björk Aradóttir , Tobias K. S. Ritschel , Henrik Bengtsson , John Bagterp Jørgensen

Calculating mealtime insulin doses poses a significant challenge for individuals with Type 1 Diabetes (T1D). Doses should perfectly compensate for expected post-meal glucose excursions, requiring a profound understanding of the individual's…

定量方法 · 定量生物学 2024-06-24 Anas El Fathi , Elliott Pryor , Marc D. Breton

This study explored healthcare professionals' perspectives on the management of Type 1 Diabetes Mellitus (T1DM) through a two-part questionnaire. The first part examined how clinicians prioritise and apply current clinical guidelines,…

人机交互 · 计算机科学 2026-03-27 Mohammed Basheikh , Rujiravee Kongdee , Hood Thabit , Bijan Parsia , Sarah Clinch , Simon Harper

People with Type 1 diabetes (T1D) require regular exogenous infusion of insulin to maintain their blood glucose concentration in a therapeutically adequate target range. Although the artificial pancreas and continuous glucose monitoring…

信号处理 · 电气工程与系统科学 2020-09-08 Taiyu Zhu , Kezhi Li , Pau Herrero , Pantelis Georgiou

We present a fully closed-loop design for an artificial pancreas (AP) which regulates the delivery of insulin for the control of Type I diabetes. Our AP controller operates in a fully automated fashion, without requiring any manual…

系统与控制 · 计算机科学 2017-09-29 Nicola Paoletti , Kin Sum Liu , Scott A. Smolka , Shan Lin

Disease progression varies with age and is influenced by underlying genetic, biochemical, and hormonal etiologies, suggesting the need for tailored monitoring, care, and medication beyond standard clinical guidelines. Specifically, in…

机器学习 · 计算机科学 2026-04-28 Beyza Cinar , Maria Maleshkova

Diabetes is one of the most prevalent diseases worldwide, characterized by persistently high blood sugar levels, capable of damaging various internal organs and systems. Diabetes patients require routine check-ups, resulting in a time…

机器学习 · 计算机科学 2025-05-13 Onthada Preedasawakul , Nathakhun Wiroonsri

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

机器学习 · 计算机科学 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Managing Type 1 diabetes (T1D) aims to optimize glucose levels within the target range while minimizing hyperglycemia and hypoglycemia. Exercise presents additional challenges due to complex effects on glucose dynamics. Despite advancements…

定量方法 · 定量生物学 2025-04-03 Ahtsham Zafar , Abiodun Solanke , Dana M. Lewis , Arsalan Shahid

In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…

定量方法 · 定量生物学 2022-09-22 M. Sirlanci , M. E. Levine , C. C. Low Wang , D. J. Albers , A. M. Stuart