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The principles of neural encoding and computations are inherently collective and usually involve large populations of interacting neurons with highly correlated activities. While theories of neural function have long recognized the…

神经元与认知 · 定量生物学 2019-05-14 Christophe Gardella , Olivier Marre , Thierry Mora

Rapid experimental advances now enable simultaneous electrophysiological recording of neural activity at single-cell resolution across large regions of the nervous system. Models of this neural network activity will necessarily increase in…

神经元与认知 · 定量生物学 2017-10-02 Andrea K. Barreiro , Cheng Ly

Localized persistent neural activity can encode delayed estimates of continuous variables. Common experiments require that subjects store and report the feature value (e.g., orientation) of a particular cue (e.g., oriented bar on a screen)…

神经元与认知 · 定量生物学 2024-08-01 Heather L Cihak , Zachary P Kilpatrick

We describe an algorithm computing the exact value of the mean current, its variance, and higher order cumulants for stochastic driven systems. The method uses a Rayleigh-Schrodinger perturbation expansion of the generating function of the…

统计力学 · 物理学 2009-03-30 Marco Baiesi , Christian Maes , Karel Netočný

Objective. Precise control of neural systems is essential to experimental investigations of how the brain controls behavior and holds the potential for therapeutic manipulations to correct aberrant network states. Model predictive control,…

神经元与认知 · 定量生物学 2024-08-06 Christof Fehrman , C. Daniel Meliza

We propose a copula-based extension of the hidden Markov model (HMM) which applies when the observations recorded at each time in the sample are multivariate. The joint model produced by the copula extension allows decoding of the hidden…

统计方法学 · 统计学 2024-05-13 Robert Zimmerman , Radu V. Craiu , Vianey Leos-Barajas

The study of plasticity in spiking neural networks is an active area of research. However, simulations that involve complex plasticity rules, dense connectivity/high synapse counts, complex neuron morphologies, or extended simulation times…

神经与进化计算 · 计算机科学 2024-12-05 Philipp Spilger , Eric Müller , Johannes Schemmel

Neural network design has utilized flexible nonlinear processes which can mimic biological systems, but has suffered from a lack of traceability in the resulting network. Graphical probabilistic models ground network design in probabilistic…

机器学习 · 计算机科学 2015-06-19 Kenric P. Nelson , Madalina Barbu , Brian J. Scannell

Spike trains data find a growing list of applications in computational neuroscience, imaging, streaming data and finance. Machine learning strategies for spike trains are based on various neural network and probabilistic models. The…

信息论 · 计算机科学 2023-08-10 Mirosław Pawlak , Mateusz Pabian , Dominik Rzepka

We characterize a Hawkes point process with kernel proportional to the probability density function of Mittag-Leffler random variables. This kernel decays as a power law with exponent $\beta +1 \in (1,2]$. Several analytical results can be…

We study the spike statistics of neurons in a network with dynamically balanced excitation and inhibition. Our model, intended to represent a generic cortical column, comprises randomly connected excitatory and inhibitory leaky…

神经元与认知 · 定量生物学 2007-05-23 Alexander Lerchner , Cristina Ursta , John Hertz , Mandana Ahmadi , Pauline Ruffiot

Particle Markov Chain Monte Carlo methods are used to carry out inference in non-linear and non-Gaussian state space models, where the posterior density of the states is approximated using particles. Current approaches usually perform…

统计计算 · 统计学 2019-09-30 Eduardo F. Mendes , Christopher K. Carter , David Gunawan , Robert Kohn

Second derivatives of mathematical models for real-world phenomena are fundamental ingredients of a wide range of numerical simulation methods including parameter sensitivity analysis, uncertainty quantification, nonlinear optimization and…

数学软件 · 计算机科学 2021-10-27 Uwe Naumann , Shubhaditya Burela

In this paper we provide an expansion formula for Hawkes processes which involves the addition of jumps at deterministic times to the Hawkes process in the spirit of the well-known integration by parts formula (or more precisely the Mecke…

概率论 · 数学 2021-04-06 Caroline Hillairet , Anthony Reveillac , Mathieu Rosenbaum

We introduce a multivariate Hawkes process with constraints on its conditional density. It is a multivariate point process with conditional intensity similar to that of a multivariate Hawkes process but certain events are forbidden with…

应用统计 · 统计学 2014-02-14 Ban Zheng , François Roueff , Frédéric Abergel

A spiking neuron ``computes'' by transforming a complex dynamical input into a train of action potentials, or spikes. The computation performed by the neuron can be formulated as dimensional reduction, or feature detection, followed by a…

生物物理 · 物理学 2007-05-23 Blaise Aguera y Arcas , Adrienne L. Fairhall , William Bialek

The Hawkes process has become a standard method for modeling self-exciting event sequences with different event types. A recent work has generalized the Hawkes process to a neurally self-modulating multivariate point process, which enables…

机器学习 · 计算机科学 2020-06-16 Zhen Han , Yunpu Ma , Yuyi Wang , Stephan Günnemann , Volker Tresp

Neural decoding may be formulated as dynamic state estimation (filtering) based on point process observations, a generally intractable problem. Numerical sampling techniques are often practically useful for the decoding of real neural data.…

神经元与认知 · 定量生物学 2019-01-15 Yuval Harel , Ron Meir , Manfred Opper

Within the framework of random multiplicative energy cascade models of fully developed turbulence, expressions for two-point correlators and cumulants are derived, taking into account a proper conversion from an ultrametric to an Euclidean…

Quantification of information content and its temporal variation in intracellular calcium spike trains in neurons helps one understand functions such as memory, learning, and cognition. Such quantification could also reveal pathological…

信号处理 · 电气工程与系统科学 2021-02-02 Sathish Ande , Srinivas Avasarala , Jayanth R Regatti , Neha Pandey , Sarpras Swain , Ajith Karunarathne , Lopamudra Giri , Soumya Jana