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Many population genetic models have been developed for the purpose of inferring population size and growth rates from random samples of genetic data. We examine two popular approaches to this problem, the coalescent and the…

种群与进化 · 定量生物学 2014-08-29 Erik M. Volz , Simon DW Frost

Stochastic models that incorporate birth, death and immigration (also called birth-death and innovation models) are ubiquitous and applicable to many research topics such as quantifying species sizes in ecological populations, describing…

种群与进化 · 定量生物学 2026-05-12 Renaud Dessalles , Maria D'Orsogna , Tom Chou

We present a flexible branching process model for cell population dynamics in synchrony/time-series experiments used to study important cellular processes. Its formulation is constructive, based on an accounting of the unique cohorts in the…

应用统计 · 统计学 2010-09-30 David A. Orlando , Edwin S. Iversen , Alexander J. Hartemink , Steven B. Haase

Self-organisation of individuals within large collectives occurs throughout biology. Mathematical models can help elucidate the individual-level mechanisms behind these dynamics, but analytical tractability often comes at the cost of…

Coalescent theory combined with statistical modeling allows us to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. When sequences are sampled serially through…

种群与进化 · 定量生物学 2021-11-02 Michael D. Karcher , Marc A. Suchard , Gytis Dudas , Vladimir N. Minin

State-space models are commonly used to describe different forms of ecological data. We consider the case of count data with observation errors. For such data the system process is typically multi-dimensional consisting of coupled Markov…

统计方法学 · 统计学 2017-08-15 Axel Finke , Ruth King , Alexandros Beskos , Petros Dellaportas

Data on count processes arise in a variety of applications, including longitudinal, spatial and imaging studies measuring count responses. The literature on statistical models for dependent count data is dominated by models built from…

统计方法学 · 统计学 2013-10-08 Antonio Canale , David B. Dunson

The paper studies the counting process arising as a subset of births and deaths in a birth--death process on a finite state space. Whenever a birth or death occurs, the process is incremented or not depending on the outcome of an…

概率论 · 数学 2026-01-13 Daryl. J. Daley , Yoni Nazarathy , Jiesen Wang

In this paper we study the iterated birth process of which we examine the first-passage time distributions and the hitting probabilities. Furthermore, linear birth processes, linear and sublinear death processes at Poisson times are…

概率论 · 数学 2016-03-23 L. Beghin , E. Orsingher

Consider a continuous-time binary branching process conditioned to have population size n at some time t, and with a chance p for recording each extinct individual in the process. Within the family tree of this process, we consider the…

概率论 · 数学 2007-05-23 Lea Popovic

In human microbiome studies, sequencing reads data are often summarized as counts of bacterial taxa at various taxonomic levels specified by a taxonomic tree. This paper considers the problem of analyzing two repeated measurements of…

应用统计 · 统计学 2017-02-17 Pixu Shi , Hongzhe Li

In the last decade, sequential Monte-Carlo methods (SMC) emerged as a key tool in computational statistics. These algorithms approximate a sequence of distributions by a sequence of weighted empirical measures associated to a weighted…

统计理论 · 数学 2007-06-13 R. Douc , France E. Moulines

This article introduces new methods for inference with count data registered on a set of aggregation units. Such data are omnipresent in epidemiology due to confidentiality issues: it is much more common to know the county in which an…

统计方法学 · 统计学 2017-04-20 Benjamin M. Taylor , Ricardo Andrade-Pacheco , Hugh J. W. Sturrock

Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…

种群与进化 · 定量生物学 2025-06-04 Linh Huynh , Jacob G. Scott , Peter J. Thomas

In this paper, we use a linear birth and death process with immigration to model infectious disease propagation when contamination stems from both person-to-person contact and contact with the environment. Our aim is to estimate the…

统计理论 · 数学 2024-01-11 Ibrahim Bouzalmat , Benoîte de Saporta , Solym M. Manou-Abi

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

种群与进化 · 定量生物学 2018-07-19 George W. A. Constable , Alan J. McKane

Genetic data are often used to infer demographic history and changes or detect genes under selection. Inferential methods are commonly based on models making various strong assumptions: demography and population structures are supposed…

种群与进化 · 定量生物学 2020-07-28 Clotilde Lepers , Sylvain Billiard , Matthieu Porte , Sylvie Méléard , Viet Chi Tran

Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with $n$ alterations, and how long will…

种群与进化 · 定量生物学 2023-07-07 Michael D. Nicholson , David Cheek , Tibor Antal

We study a universal object for the genealogy of a sample in populations with mutations: the critical birth-death process with Poissonian mutations, conditioned on its population size at a fixed time horizon. We show how this process arises…

概率论 · 数学 2014-07-30 G. Achaz , C. Delaporte , A. Lambert

Multivariate count data are defined as the number of items of different categories issued from sampling within a population, which individuals are grouped into categories. The analysis of multivariate count data is a recurrent and crucial…

机器学习 · 统计学 2013-12-17 Pierre Fernique , Jean-Baptiste Durand , Yann Guédon
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