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In the present article, we investigate the effects of dormancy on an abstract population genetic level. We first provide a short review of seed bank models in population genetics, and the role of dormancy for the interplay of evolutionary…

概率论 · 数学 2020-12-03 Jochen Blath , Noemi Kurt

The goal of this article is to contribute towards the conceptual and quantitative understanding of the evolutionary benefits for (microbial) populations to maintain a seed bank (consisting of dormant individuals) when facing fluctuating…

概率论 · 数学 2024-07-02 Jochen Blath , Felix Hermann , Martin Slowik

We identify a new natural coalescent structure, which we call the seed-bank coalescent, that describes the gene genealogy of populations under the influence of a strong seed-bank effect, where "dormant forms" of individuals (such as seeds…

Across the tree of life, populations have evolved the capacity to contend with suboptimal conditions by engaging in dormancy, whereby individuals enter a reversible state of reduced metabolic activity. The resulting seed banks are complex,…

种群与进化 · 定量生物学 2025-02-10 Jay T. Lennon , Frank den Hollander , Maite Wilke-Berenguer , Jochen Blath

Graphs are used to represent and analyze data in domains as diverse as physics, biology, chemistry, planetary science, and the social sciences. Across domains, random graph models relate generative processes to expected graph properties,…

物理与社会 · 物理学 2025-09-12 Cole Mathis , Harrison B. Smith

We introduce a model for a growing random graph based on simultaneous reproduction of the vertices. The model can be thought of as a generalisation of the reproducing graphs of Southwell and Cannings and Bonato et al to allow for a random…

概率论 · 数学 2011-04-20 Jonathan Jordan

We study how changes in population size and fluctuating environmental conditions influence the establishment of seed banks in plants. Our model is a modification of the Wright-Fisher model with seed bank, introduced by Kaj, Krone and…

概率论 · 数学 2026-02-05 Alison Etheridge , João Luiz de Oliveira Madeira

Random graphs are more and more used for modeling real world networks such as evolutionary networks of proteins. For this purpose we look at two different models and analyze how properties like connectedness and degree distributions are…

概率论 · 数学 2019-02-05 Klemens Taglieber , Uta Freiberg

Seed banks are a common characteristics to many plant species, which allow storage of genetic diversity in the soil as dormant seeds for various periods of time. We investigate an above-ground population following a Fisher-Wright model with…

种群与进化 · 定量生物学 2017-01-13 Bendix Koopmann , Johannes Müller , Aurélien Tellier , Daniel Živković

Despite the enormous success of graph neural networks (GNNs), most existing GNNs can only be applicable to undirected graphs where relationships among connected nodes are two-way symmetric (i.e., information can be passed back and forth).…

机器学习 · 计算机科学 2021-10-15 Zhuo Tan , Bin Liu , Guosheng Yin

Gene interaction graphs aim to capture various relationships between genes and can represent decades of biology research. When trying to make predictions from genomic data, those graphs could be used to overcome the curse of dimensionality…

Migrations have played an important role in shaping the genetic diversity of human populations. Understanding genomic data thus requires careful modeling of historical gene flow. Here we consider the effect of relatively recent population…

种群与进化 · 定量生物学 2012-04-26 Simon Gravel

We investigate the $\Lambda$-Seed-Bank-Wright-Fisher process, a model describing allele frequency dynamics in populations exhibiting both skewed offspring distributions and dormancy. By performing a change of measure, we condition this…

We develop novel hierarchical reciprocal graphical models to infer gene networks from heterogeneous data. In the case of data that can be naturally divided into known groups, we propose to connect graphs by introducing a hierarchical prior…

统计方法学 · 统计学 2018-01-23 Yang Ni , Peter Mueller , Yitan Zhu , Yuan Ji

We investigate the behaviour of the genealogy of a Wright-Fisher population model under the influence of a strong seed-bank effect. More precisely, we consider a simple seed-bank age distribution with two atoms, leading to either classical…

概率论 · 数学 2014-03-13 Jochen Blath , Bjarki Eldon , Adrián González Casanova , Noemi Kurt

Gene conversion is a mechanism by which a double-strand break in a DNA molecule is repaired using a homologous DNA molecule as a template. As a result, one gene is 'copied and pasted' onto the other gene. It was recently reported that the…

种群与进化 · 定量生物学 2013-04-08 Shuhei Mano

Stationarity is a cornerstone property that facilitates the analysis and processing of random signals in the time domain. Although time-varying signals are abundant in nature, in many practical scenarios the information of interest resides…

系统与控制 · 计算机科学 2017-10-11 Antonio G. Marques , Santiago Segarra , Geert Leus , Alejandro Ribeiro

Understanding the population structure and patterns of gene flow within species is of fundamental importance to the study of evolution. In the fields of population and evolutionary genetics, measures of genetic differentiation are commonly…

种群与进化 · 定量生物学 2016-09-27 Lisa Sundqvist , Kevin Keenan , Martin Zackrisson , Paulo Prodöhl , David Kleinhans

Graph representations offer powerful and intuitive ways to describe data in a multitude of application domains. Here, we consider stochastic processes generating graphs and propose a methodology for detecting changes in stationarity of such…

机器学习 · 计算机科学 2021-02-11 Daniele Zambon , Cesare Alippi , Lorenzo Livi

In this paper we will provide an introductory understanding of random graph models, and matchings in the case of Erdos-Renyi random graphs. We will provide a synthesis of background theory to this end. We will further examine pertinent…

统计理论 · 数学 2019-11-18 Lucas Rooney
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