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We consider the problem of estimating and inferring treatment effects in randomized experiments. In practice, stratified randomization, or more generally, covariate-adaptive randomization, is routinely used in the design stage to balance…

统计方法学 · 统计学 2022-09-27 Hanzhong Liu , Fuyi Tu , Wei Ma

Deep neural network models have demonstrated their effectiveness in classifying multi-label data from various domains. Typically, they employ a training mode that combines mini-batches with optimizers, where each sample is randomly selected…

机器学习 · 计算机科学 2024-03-28 Ao Zhou , Bin Liu , Jin Wang , Grigorios Tsoumakas

Adapting to dynamic data distributions is a practical yet challenging task. One effective strategy is to use a model ensemble, which leverages the diverse expertise of different models to transfer knowledge to evolving data distributions.…

Typically, case-control studies to estimate odds-ratios associating risk factors with disease incidence from logistic regression only include cases with newly diagnosed disease. Recently proposed methods allow incorporating information on…

统计方法学 · 统计学 2020-10-19 Soutrik Mandal , Jing Qin , Ruth M. Pfeiffer

In observational studies, covariate imbalance generates confounding, resulting in biased comparisons. Although propensity score-based weighting approaches facilitate unconfounded group comparisons for implicit target populations, existing…

统计方法学 · 统计学 2023-07-03 Subharup Guha , David C. Christiani , Yi Li

Generalizing causal estimates in randomized experiments to a broader target population is essential for guiding decisions by policymakers and practitioners in the social and biomedical sciences. While recent papers developed various…

统计方法学 · 统计学 2021-11-03 Melody Huang , Naoki Egami , Erin Hartman , Luke Miratrix

Batch Normalization (BN) and its variants have delivered tremendous success in combating the covariate shift induced by the training step of deep learning methods. While these techniques normalize feature distributions by standardizing with…

机器学习 · 计算机科学 2021-05-06 Mandy Lu , Qingyu Zhao , Jiequan Zhang , Kilian M. Pohl , Li Fei-Fei , Juan Carlos Niebles , Ehsan Adeli

For predicting cancer survival outcomes, standard approaches in clinical research are often based on two main modalities: pathology images for observing cell morphology features, and genomic (e.g., bulk RNA-seq) for quantifying gene…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Hongxiao Wang , Yang Yang , Zhuo Zhao , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

Batch effects represent a major confounder in genomic diagnostics. In copy number variant (CNV) detection from NGS, many algorithms compare read depth between test samples and a reference sample, assuming they are process-matched. When this…

基因组学 · 定量生物学 2026-01-16 Austin Talbot , Yue Ke

Randomized Controlled Trials (RCTs) represent a gold standard when developing policy guidelines. However, RCTs are often narrow, and lack data on broader populations of interest. Causal effects in these populations are often estimated using…

机器学习 · 计算机科学 2023-03-07 Zeshan Hussain , Michael Oberst , Ming-Chieh Shih , David Sontag

Clinical machine learning applications are often plagued with confounders that are clinically irrelevant, but can still artificially boost the predictive performance of the algorithms. Confounding is especially problematic in mobile health…

应用统计 · 统计学 2018-11-29 Elias Chaibub Neto

One popular example of metaheuristic algorithms from the swarm intelligence family is the Bat algorithm (BA). The algorithm was first presented in 2010 by Yang and quickly demonstrated its efficiency in comparison with other common…

Estimating causal effects on time-to-event outcomes from observational data is particularly challenging due to censoring, limited sample sizes, and non-random treatment assignment. The need for answering such "when-if" questions--how the…

机器学习 · 计算机科学 2025-11-19 Jessy Xinyi Han , Devavrat Shah

A typical random effects meta-analysis of odds-ratios assumes binomially distributed numbers of events in a treatment and control group and requires the proportion of deaths to be extracted from published papers. This data is often not…

统计方法学 · 统计学 2014-10-13 Shemra Rizzo , Robert E. Weiss

Traditional resampling methods for handling class imbalance typically uses fixed distributions, undersampling the majority or oversampling the minority. These static strategies ignore changes in class-wise learning difficulty, which can…

机器学习 · 计算机科学 2026-02-17 Arjun Basandrai , Shourya Jain , K. Ilanthenral

Clinical study populations often differ meaningfully from the broader populations to which results are intended to generalize. Weighting methods such as inverse probability of sampling weights (IPSW) reweight study participants to resemble…

统计方法学 · 统计学 2025-12-02 William Stewart , Carly L. Brantner , Elizabeth A. Stuart , Laine Thomas

This paper presents a new approach for batch Bayesian Optimization (BO) called Thompson Sampling-Regret to Sigma Ratio directed sampling (TS-RSR), where we sample a new batch of actions by minimizing a Thompson Sampling approximation of a…

机器学习 · 计算机科学 2025-06-10 Zhaolin Ren , Na Li

Adam is one of the most influential adaptive stochastic algorithms for training deep neural networks, which has been pointed out to be divergent even in the simple convex setting via a few simple counterexamples. Many attempts, such as…

机器学习 · 计算机科学 2022-08-09 Congliang Chen , Li Shen , Fangyu Zou , Wei Liu

This paper develops a novel stochastic tree ensemble method for nonlinear regression, which we refer to as XBART, short for Accelerated Bayesian Additive Regression Trees. By combining regularization and stochastic search strategies from…

机器学习 · 统计学 2021-06-04 Jingyu He , P. Richard Hahn

Test-Time Adaptation aims to adapt source domain model to testing data at inference stage with success demonstrated in adapting to unseen corruptions. However, these attempts may fail under more challenging real-world scenarios. Existing…

机器学习 · 计算机科学 2025-03-27 Yongyi Su , Xun Xu , Kui Jia
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