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Prediction of survival for cancer patients is an open area of research. However, many of these studies focus on datasets with a large number of patients. We present a novel method that is specifically designed to address the challenge of…

机器学习 · 计算机科学 2015-09-30 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Randomization tests are a popular method for testing causal effects in clinical trials with finite-sample validity. In the presence of heterogeneous treatment effects, it is often of interest to select a subgroup that benefits from the…

统计方法学 · 统计学 2025-04-29 Zijun Gao

Randomized experiments can provide unbiased estimates of sample average treatment effects. However, estimates of population treatment effects can be biased when the experimental sample and the target population differ. In this case, the…

统计方法学 · 统计学 2022-11-10 Wenqi Shi , Xi Lin

The survey experiment is widely used in economics and social sciences to evaluate the effects of treatments or programs. In a standard population-based survey experiment, the experimenter randomly draws experimental units from a target…

统计方法学 · 统计学 2026-05-11 Pengfei Tian , Jiyang Ren , Yingying Ma

With an increasing focus on precision medicine in medical research, numerous studies have been conducted in recent years to clarify the relationship between treatment effects and patient characteristics. The treatment effects for patients…

统计方法学 · 统计学 2023-09-22 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

Methods for estimating heterogeneous treatment effects (HTE) from observational data have largely focused on continuous or binary outcomes, with less attention paid to survival outcomes and almost none to settings with competing risks. In…

统计方法学 · 统计学 2024-09-30 Shenbo Xu , Raluca Cobzaru , Stan N. Finkelstein , Roy E. Welsch , Kenney Ng , Zach Shahn

This paper proposes an adaptive randomization procedure for two-stage randomized controlled trials. The method uses data from a first-wave experiment in order to determine how to stratify in a second wave of the experiment, where the…

计量经济学 · 经济学 2022-07-06 Max Tabord-Meehan

After selection with the Group LASSO (or generalized variants such as the overlapping, sparse, or standardized Group LASSO), inference for the selected parameters is unreliable in the absence of adjustments for selection bias. In the…

统计方法学 · 统计学 2022-08-16 Snigdha Panigrahi , Peter W. MacDonald , Daniel Kessler

Background and Objective: Colorectal cancer is a high mortality cancer. Clinical data analysis plays a crucial role in predicting the survival of colorectal cancer patients, enabling clinicians to make informed treatment decisions. However,…

机器学习 · 计算机科学 2023-09-06 Sadegh Soleimani , Mahsa Bahrami , Mansour Vali

Background: For RCTs with time-to-event endpoints, proportional hazard (PH) models are typically used to estimate treatment effects and logrank tests are commonly used for hypothesis testing. There is growing support for replacing this…

统计方法学 · 统计学 2024-12-10 Dominic Magirr , Craig Wang , Xinlei Deng , Tim Morris , Mark Baillie

The advanced capabilities of Large Language Models (LLMs) have inspired the development of various interactive web services or applications, such as ChatGPT, which offer query inference services for users. Unlike traditional DNN model, the…

机器学习 · 计算机科学 2024-10-25 Peizhuang Cong , Qizhi Chen , Haochen Zhao , Tong Yang

Bayesian Additive Regression Trees (BART) is a popular Bayesian non-parametric regression algorithm. The posterior is a distribution over sums of decision trees, and predictions are made by averaging approximate samples from the posterior.…

机器学习 · 统计学 2022-10-19 Omer Ronen , Theo Saarinen , Yan Shuo Tan , James Duncan , Bin Yu

Identifying patient subgroups with different treatment responses is an important task to inform medical recommendations, guidelines, and the design of future clinical trials. Existing approaches for treatment effect estimation primarily…

统计方法学 · 统计学 2025-12-10 Vincent Jeanselme , Chang Ho Yoon , Fabian Falck , Brian Tom , Jessica Barrett

In the analysis of survey data, sampling weights are needed for consistent estimation of the population. However, the original inverse probability weights from the survey sample design are typically modified to account for non-response, to…

统计计算 · 统计学 2025-08-19 Matthew R. Williams , Terrance D. Savitsky

Variational inequalities are a universal optimization paradigm that incorporate classical minimization and saddle point problems. Nowadays more and more tasks require to consider stochastic formulations of optimization problems. In this…

We propose a new framework of CatBoost that predicts the entire conditional distribution of a univariate response variable. In particular, CatBoostLSS models all moments of a parametric distribution (i.e., mean, location, scale and shape…

机器学习 · 统计学 2020-01-08 Alexander März

In the presence of heterogeneity between the randomized controlled trial (RCT) participants and the target population, evaluating the treatment effect solely based on the RCT often leads to biased quantification of the real-world treatment…

统计方法学 · 统计学 2022-10-05 Dasom Lee , Shu Yang , Xiaofei Wang

In a split conformal framework with $K$ classes, a calibration sample of $n$ labeled examples is observed for inference on the label of a new unlabeled example. We explore the setting where a `batch' of $m$ independent such unlabeled…

统计方法学 · 统计学 2025-03-19 Ulysse Gazin , Ruth Heller , Etienne Roquain , Aldo Solari

Batch Normalization is quite effective at accelerating and improving the training of deep models. However, its effectiveness diminishes when the training minibatches are small, or do not consist of independent samples. We hypothesize that…

机器学习 · 计算机科学 2017-03-31 Sergey Ioffe

Decisions based upon pairwise comparisons of multiple treatments are naturally performed in terms of the mean survival of the selected study arms or functions thereof. However, synthesis of treatment comparisons is usually performed on…

应用统计 · 统计学 2025-12-11 Anastasios Apsemidis , Dimitris Mavridis , Nikolaos Demiris